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Dietary glycemic index, glycemic load, and cardiovascular disease risk factors: Tehran Lipid and Glucose Study.
Arch Iran Med 2013; 16(7):401-7AI

Abstract

BACKGROUND

Data available on the effect of quality (glycemic index [GI]) and quantity (glycemic load [GL]) of carbohydrates on the risk factors of cardiovascular disease (CVD) are inconsistent. The objective of this study was to examine the association between dietary GI, GL, and CVD risk factors among Tehranian adults, the participants of the Tehran Lipid and Glucose Study.

METHODS

This population- based cross-sectional study was conducted on 2457 subjects (46% men and 54% women), aged 19 to 84 years. Dietary GI and GL were measured using a validated 168- item semiquantitative food frequency questionnaire. Anthropometrics, blood pressure, fasting blood glucose, and lipid profiles were measured.

RESULTS

The mean intakes of GI and GL were 68.3 and 244.8, respectively. Rice (26.6%) and bread (19.0%) were the major contributors to dietary GI and GL, respectively. Higher dietary GI and GL were associated with high intakes of carbohydrate, fiber, refined grain, fruits, simple sugar, snack, and desserts. After adjustment for lifestyle and dietary variables, a higher dietary GI was positively associated with triglycerides and high-density lipoprotein (HDL) cholesterol concentrations among obese subjects. Dietary GL was positively associated with fasting and 2-h blood glucose among nonobese subjects, after adjustment for confounders.

CONCLUSION

Dietary GI and GL were associated with a few CVD risk factors, and body mass index levels may modulate these associations.

Authors+Show Affiliations

Nutrition and Endocrine Research Center, Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23808777

Citation

Hosseinpour-Niazi, Somayeh, et al. "Dietary Glycemic Index, Glycemic Load, and Cardiovascular Disease Risk Factors: Tehran Lipid and Glucose Study." Archives of Iranian Medicine, vol. 16, no. 7, 2013, pp. 401-7.
Hosseinpour-Niazi S, Sohrab G, Asghari G, et al. Dietary glycemic index, glycemic load, and cardiovascular disease risk factors: Tehran Lipid and Glucose Study. Arch Iran Med. 2013;16(7):401-7.
Hosseinpour-Niazi, S., Sohrab, G., Asghari, G., Mirmiran, P., Moslehi, N., & Azizi, F. (2013). Dietary glycemic index, glycemic load, and cardiovascular disease risk factors: Tehran Lipid and Glucose Study. Archives of Iranian Medicine, 16(7), pp. 401-7. doi:013167/AIM.008.
Hosseinpour-Niazi S, et al. Dietary Glycemic Index, Glycemic Load, and Cardiovascular Disease Risk Factors: Tehran Lipid and Glucose Study. Arch Iran Med. 2013;16(7):401-7. PubMed PMID: 23808777.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary glycemic index, glycemic load, and cardiovascular disease risk factors: Tehran Lipid and Glucose Study. AU - Hosseinpour-Niazi,Somayeh, AU - Sohrab,Golbon, AU - Asghari,Golaleh, AU - Mirmiran,Parvin, AU - Moslehi,Nazanin, AU - Azizi,Fereidoun, PY - 2013/7/2/entrez PY - 2013/7/3/pubmed PY - 2013/10/18/medline SP - 401 EP - 7 JF - Archives of Iranian medicine JO - Arch Iran Med VL - 16 IS - 7 N2 - BACKGROUND: Data available on the effect of quality (glycemic index [GI]) and quantity (glycemic load [GL]) of carbohydrates on the risk factors of cardiovascular disease (CVD) are inconsistent. The objective of this study was to examine the association between dietary GI, GL, and CVD risk factors among Tehranian adults, the participants of the Tehran Lipid and Glucose Study. METHODS: This population- based cross-sectional study was conducted on 2457 subjects (46% men and 54% women), aged 19 to 84 years. Dietary GI and GL were measured using a validated 168- item semiquantitative food frequency questionnaire. Anthropometrics, blood pressure, fasting blood glucose, and lipid profiles were measured. RESULTS: The mean intakes of GI and GL were 68.3 and 244.8, respectively. Rice (26.6%) and bread (19.0%) were the major contributors to dietary GI and GL, respectively. Higher dietary GI and GL were associated with high intakes of carbohydrate, fiber, refined grain, fruits, simple sugar, snack, and desserts. After adjustment for lifestyle and dietary variables, a higher dietary GI was positively associated with triglycerides and high-density lipoprotein (HDL) cholesterol concentrations among obese subjects. Dietary GL was positively associated with fasting and 2-h blood glucose among nonobese subjects, after adjustment for confounders. CONCLUSION: Dietary GI and GL were associated with a few CVD risk factors, and body mass index levels may modulate these associations. SN - 1735-3947 UR - https://www.unboundmedicine.com/medline/citation/23808777/Dietary_glycemic_index_glycemic_load_and_cardiovascular_disease_risk_factors:_Tehran_Lipid_and_Glucose_Study_ L2 - http://www.ams.ac.ir/AIM/NEWPUB/13/16/7/008.pdf DB - PRIME DP - Unbound Medicine ER -