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A systematic review of magnesium therapy for treating attention deficit hyperactivity disorder.

Abstract

There are contradictory reports about the association of magnesium and attention- deficit hyperactivity disorder (ADHD). Moreover, some studies reported that magnesium is effective for treating ADHD. This is the first systematic review evaluating the effectiveness of magnesium to treat patients with ADHD. The two databases of MEDLINE/ PubMedline and Google Scholar were electronically searched using the search items and considering inclusion and exclusion criteria. Out of the 37 titles, only six studies were experimental interventional studies. However, three of these studies were without any control group. The other three studies were controlled clinical trials. Nevertheless, none of the studies was a randomized double- blind controlled clinical trial. These studies supported that magnesium is effective for treating ADHD. Magnesium monotherapy studies were not found. There is no well- controlled clinical trial investigating the efficacy and safety of magnesium for treating ADHD. In addition, the safety of magnesium in ADHD is ignored. Therefore, until further strong evidences for its efficacy and safety are provided, magnesium is not recommended for treating ADHD.

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  • Authors+Show Affiliations

    Research Center for Psychiatry and Behavioral Sciences, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. ghanizad@sina.tums.ac.ir

    Source

    Archives of Iranian medicine 16:7 2013 Jul pg 412-7

    MeSH

    Attention Deficit Disorder with Hyperactivity
    Humans
    Magnesium

    Pub Type(s)

    Journal Article
    Review
    Systematic Review

    Language

    eng

    PubMed ID

    23808779

    Citation

    Ghanizadeh, Ahmad. "A Systematic Review of Magnesium Therapy for Treating Attention Deficit Hyperactivity Disorder." Archives of Iranian Medicine, vol. 16, no. 7, 2013, pp. 412-7.
    Ghanizadeh A. A systematic review of magnesium therapy for treating attention deficit hyperactivity disorder. Arch Iran Med. 2013;16(7):412-7.
    Ghanizadeh, A. (2013). A systematic review of magnesium therapy for treating attention deficit hyperactivity disorder. Archives of Iranian Medicine, 16(7), pp. 412-7. doi:013167/AIM.0010.
    Ghanizadeh A. A Systematic Review of Magnesium Therapy for Treating Attention Deficit Hyperactivity Disorder. Arch Iran Med. 2013;16(7):412-7. PubMed PMID: 23808779.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - A systematic review of magnesium therapy for treating attention deficit hyperactivity disorder. A1 - Ghanizadeh,Ahmad, PY - 2013/7/2/entrez PY - 2013/7/3/pubmed PY - 2013/10/18/medline SP - 412 EP - 7 JF - Archives of Iranian medicine JO - Arch Iran Med VL - 16 IS - 7 N2 - There are contradictory reports about the association of magnesium and attention- deficit hyperactivity disorder (ADHD). Moreover, some studies reported that magnesium is effective for treating ADHD. This is the first systematic review evaluating the effectiveness of magnesium to treat patients with ADHD. The two databases of MEDLINE/ PubMedline and Google Scholar were electronically searched using the search items and considering inclusion and exclusion criteria. Out of the 37 titles, only six studies were experimental interventional studies. However, three of these studies were without any control group. The other three studies were controlled clinical trials. Nevertheless, none of the studies was a randomized double- blind controlled clinical trial. These studies supported that magnesium is effective for treating ADHD. Magnesium monotherapy studies were not found. There is no well- controlled clinical trial investigating the efficacy and safety of magnesium for treating ADHD. In addition, the safety of magnesium in ADHD is ignored. Therefore, until further strong evidences for its efficacy and safety are provided, magnesium is not recommended for treating ADHD. SN - 1735-3947 UR - https://www.unboundmedicine.com/medline/citation/23808779/A_systematic_review_of_magnesium_therapy_for_treating_attention_deficit_hyperactivity_disorder_ L2 - http://www.ams.ac.ir/AIM/NEWPUB/13/16/7/0010.pdf DB - PRIME DP - Unbound Medicine ER -