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"Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses.
Arch Virol. 2013 Dec; 158(12):2517-21.AV

Abstract

The nucleocytoplasmic large DNA viruses (NCLDVs) comprise a monophyletic group of viruses that infect animals and diverse unicellular eukaryotes. The NCLDV group includes the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae, Mimiviridae and the proposed family "Marseilleviridae". The family Mimiviridae includes the largest known viruses, with genomes in excess of one megabase, whereas the genome size in the other NCLDV families varies from 100 to 400 kilobase pairs. Most of the NCLDVs replicate in the cytoplasm of infected cells, within so-called virus factories. The NCLDVs share a common ancient origin, as demonstrated by evolutionary reconstructions that trace approximately 50 genes encoding key proteins involved in viral replication and virion formation to the last common ancestor of all these viruses. Taken together, these characteristics lead us to propose assigning an official taxonomic rank to the NCLDVs as the order "Megavirales", in reference to the large size of the virions and genomes of these viruses.

Links

Publisher Full Text
ncbi.nlm.nih.gov
dx.doi.org
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Authors+Show Affiliations

Colson P
Unité des Rickettsies, URMITE UMR CNRS 7278 IRD 198 INSERM U1095, Facultés de Médecine et de Pharmacie, IHU Méditerranée Infection, Aix-Marseille Université, 27 Boulevard Jean Moulin, 13385, Marseille Cedex 05, France.
De Lamballerie X
No affiliation info available
Yutin N
No affiliation info available
Asgari S
No affiliation info available
Bigot Y
No affiliation info available
Bideshi DK
No affiliation info available
Cheng XW
No affiliation info available
Federici BA
No affiliation info available
Van Etten JL
No affiliation info available
Koonin EV
No affiliation info available
La Scola B
No affiliation info available
Raoult D
No affiliation info available

MeSH

DNA VirusesDNA, ViralEukaryotaEvolution, MolecularTerminology as Topic

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, N.I.H., Intramural

Language

eng

PubMed ID

23812617

Citation

Colson, Philippe, et al. ""Megavirales", a Proposed New Order for Eukaryotic Nucleocytoplasmic Large DNA Viruses." Archives of Virology, vol. 158, no. 12, 2013, pp. 2517-21.
Colson P, De Lamballerie X, Yutin N, et al. "Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses. Arch Virol. 2013;158(12):2517-21.
Colson, P., De Lamballerie, X., Yutin, N., Asgari, S., Bigot, Y., Bideshi, D. K., Cheng, X. W., Federici, B. A., Van Etten, J. L., Koonin, E. V., La Scola, B., & Raoult, D. (2013). "Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses. Archives of Virology, 158(12), 2517-21. https://doi.org/10.1007/s00705-013-1768-6
Colson P, et al. "Megavirales", a Proposed New Order for Eukaryotic Nucleocytoplasmic Large DNA Viruses. Arch Virol. 2013;158(12):2517-21. PubMed PMID: 23812617.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - "Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses. AU - Colson,Philippe, AU - De Lamballerie,Xavier, AU - Yutin,Natalya, AU - Asgari,Sassan, AU - Bigot,Yves, AU - Bideshi,Dennis K, AU - Cheng,Xiao-Wen, AU - Federici,Brian A, AU - Van Etten,James L, AU - Koonin,Eugene V, AU - La Scola,Bernard, AU - Raoult,Didier, Y1 - 2013/06/29/ PY - 2012/08/03/received PY - 2013/05/07/accepted PY - 2013/7/2/entrez PY - 2013/7/3/pubmed PY - 2014/1/15/medline SP - 2517 EP - 21 JF - Archives of virology JO - Arch Virol VL - 158 IS - 12 N2 - The nucleocytoplasmic large DNA viruses (NCLDVs) comprise a monophyletic group of viruses that infect animals and diverse unicellular eukaryotes. The NCLDV group includes the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae, Mimiviridae and the proposed family "Marseilleviridae". The family Mimiviridae includes the largest known viruses, with genomes in excess of one megabase, whereas the genome size in the other NCLDV families varies from 100 to 400 kilobase pairs. Most of the NCLDVs replicate in the cytoplasm of infected cells, within so-called virus factories. The NCLDVs share a common ancient origin, as demonstrated by evolutionary reconstructions that trace approximately 50 genes encoding key proteins involved in viral replication and virion formation to the last common ancestor of all these viruses. Taken together, these characteristics lead us to propose assigning an official taxonomic rank to the NCLDVs as the order "Megavirales", in reference to the large size of the virions and genomes of these viruses. SN - 1432-8798 UR - https://www.unboundmedicine.com/medline/citation/23812617/"Megavirales"_a_proposed_new_order_for_eukaryotic_nucleocytoplasmic_large_DNA_viruses_ L2 - https://dx.doi.org/10.1007/s00705-013-1768-6 DB - PRIME DP - Unbound Medicine ER -