Tags

Type your tag names separated by a space and hit enter

Acute methylone intoxication in an accidental drowning--a case report.
Forensic Sci Int 2013; 231(1-3):e1-3FS

Abstract

A 19-year-old woman who was known to use illicit drugs (ecstasy and marijuana) was found floating in the ocean 100 yards from the beach. When last seen the previous evening, she had said to a friend that she was going to "get in the water." Reports to police indicated that she "may have been on ecstasy." There were no notes of a suicidal nature, illicit drugs, drug paraphernalia, tobacco cigarettes, or alcoholic beverages at the scene. Autopsy findings were consistent with drowning. Postmortem blood initially screened positive for methamphetamine and cannabinoids by ELISA and was subsequently confirmed for methylone by a specific GC-MS SIM analysis following solid-phase extraction. Concentrations found in the peripheral blood, central blood, vitreous, liver and gastric contents were measured at 3.4 mg/L 3.4 mg/L, 4.3mg/L, 11 mg/kg, and 1.7 mg, respectively. No other amphetamine-like compound (including ecstasy) was detected. These results are discussed in relation to previous cases of toxicity, and the lack of potential for substantial methylone postmortem redistribution.

Authors+Show Affiliations

County of San Diego Medical Examiner's Office, 5570 Overland Avenue, Suite 101, San Diego, CA 92123, USA. Iain.McIntyre@sdcounty.ca.govNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

23827713

Citation

McIntyre, Iain M., et al. "Acute Methylone Intoxication in an Accidental Drowning--a Case Report." Forensic Science International, vol. 231, no. 1-3, 2013, pp. e1-3.
McIntyre IM, Hamm CE, Aldridge L, et al. Acute methylone intoxication in an accidental drowning--a case report. Forensic Sci Int. 2013;231(1-3):e1-3.
McIntyre, I. M., Hamm, C. E., Aldridge, L., & Nelson, C. L. (2013). Acute methylone intoxication in an accidental drowning--a case report. Forensic Science International, 231(1-3), pp. e1-3. doi:10.1016/j.forsciint.2013.06.005.
McIntyre IM, et al. Acute Methylone Intoxication in an Accidental Drowning--a Case Report. Forensic Sci Int. 2013 Sep 10;231(1-3):e1-3. PubMed PMID: 23827713.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute methylone intoxication in an accidental drowning--a case report. AU - McIntyre,Iain M, AU - Hamm,Catherine E, AU - Aldridge,Lenore, AU - Nelson,Craig L, Y1 - 2013/07/02/ PY - 2013/04/10/received PY - 2013/05/31/revised PY - 2013/06/09/accepted PY - 2013/7/6/entrez PY - 2013/7/6/pubmed PY - 2014/6/6/medline KW - Fatality KW - Methylone KW - Postmortem concentrations KW - Postmortem distribution KW - Redistribution SP - e1 EP - 3 JF - Forensic science international JO - Forensic Sci. Int. VL - 231 IS - 1-3 N2 - A 19-year-old woman who was known to use illicit drugs (ecstasy and marijuana) was found floating in the ocean 100 yards from the beach. When last seen the previous evening, she had said to a friend that she was going to "get in the water." Reports to police indicated that she "may have been on ecstasy." There were no notes of a suicidal nature, illicit drugs, drug paraphernalia, tobacco cigarettes, or alcoholic beverages at the scene. Autopsy findings were consistent with drowning. Postmortem blood initially screened positive for methamphetamine and cannabinoids by ELISA and was subsequently confirmed for methylone by a specific GC-MS SIM analysis following solid-phase extraction. Concentrations found in the peripheral blood, central blood, vitreous, liver and gastric contents were measured at 3.4 mg/L 3.4 mg/L, 4.3mg/L, 11 mg/kg, and 1.7 mg, respectively. No other amphetamine-like compound (including ecstasy) was detected. These results are discussed in relation to previous cases of toxicity, and the lack of potential for substantial methylone postmortem redistribution. SN - 1872-6283 UR - https://www.unboundmedicine.com/medline/citation/23827713/Acute_methylone_intoxication_in_an_accidental_drowning__a_case_report_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0379-0738(13)00327-7 DB - PRIME DP - Unbound Medicine ER -