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The use of nitazoxanide against the pathogens Ichthyophthirius multifiliis and Aeromonas hydrophila in silver catfish (Rhamdia quelen).
Vet Parasitol 2013; 197(3-4):522-6VP

Abstract

The antiparasitic and antibacterial activities of nitazoxanide (NTZ) against Ichthyophthirius multifiliis (Ich) and Aeromonas hydrophila, respectively, were evaluated in silver catfish juveniles (Rhamdia quelen). In the first experiment, fish naturally infected by Ich were treated with different concentrations of NTZ. Fish mortality and the number of trophonts/juveniles were evaluated. In the second experiment, the antimicrobial potential in vitro (MIC test) and preventive potential in vivo against A. hydrophila was evaluated. The treatment with 1.5mgL(-1) NTZ showed the best result against Ich, with a significant reduction of trophonts and fish mortality of 10%. NTZ did not show in vitro activity against A. hydrophila at concentrations tested, but showed a probable preventive activity in vivo. However, these results are preliminary and more studies should be conducted.

Authors+Show Affiliations

Laboratório de Fisiologia de Peixes-(LAFIPE), Departamento de Fisiologia e Farmacologia, Universidade Federal de Santa Maria, Santa Maria, RS BR-97105-900, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Controlled Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23830481

Citation

Sutili, Fernando J., et al. "The Use of Nitazoxanide Against the Pathogens Ichthyophthirius Multifiliis and Aeromonas Hydrophila in Silver Catfish (Rhamdia Quelen)." Veterinary Parasitology, vol. 197, no. 3-4, 2013, pp. 522-6.
Sutili FJ, Gressler LT, Vargas AC, et al. The use of nitazoxanide against the pathogens Ichthyophthirius multifiliis and Aeromonas hydrophila in silver catfish (Rhamdia quelen). Vet Parasitol. 2013;197(3-4):522-6.
Sutili, F. J., Gressler, L. T., Vargas, A. C., Zeppenfeld, C. C., Baldisserotto, B., & Cunha, M. A. (2013). The use of nitazoxanide against the pathogens Ichthyophthirius multifiliis and Aeromonas hydrophila in silver catfish (Rhamdia quelen). Veterinary Parasitology, 197(3-4), pp. 522-6. doi:10.1016/j.vetpar.2013.06.012.
Sutili FJ, et al. The Use of Nitazoxanide Against the Pathogens Ichthyophthirius Multifiliis and Aeromonas Hydrophila in Silver Catfish (Rhamdia Quelen). Vet Parasitol. 2013 Nov 8;197(3-4):522-6. PubMed PMID: 23830481.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The use of nitazoxanide against the pathogens Ichthyophthirius multifiliis and Aeromonas hydrophila in silver catfish (Rhamdia quelen). AU - Sutili,Fernando J, AU - Gressler,Leticia T, AU - Vargas,Agueda C, AU - Zeppenfeld,Carla C, AU - Baldisserotto,Bernardo, AU - Cunha,Mauro A, Y1 - 2013/06/19/ PY - 2013/02/05/received PY - 2013/06/06/revised PY - 2013/06/11/accepted PY - 2013/7/9/entrez PY - 2013/7/9/pubmed PY - 2014/5/20/medline KW - Antimicrobial KW - Antiprotozoal KW - Ich KW - Ichthyophthiriasis SP - 522 EP - 6 JF - Veterinary parasitology JO - Vet. Parasitol. VL - 197 IS - 3-4 N2 - The antiparasitic and antibacterial activities of nitazoxanide (NTZ) against Ichthyophthirius multifiliis (Ich) and Aeromonas hydrophila, respectively, were evaluated in silver catfish juveniles (Rhamdia quelen). In the first experiment, fish naturally infected by Ich were treated with different concentrations of NTZ. Fish mortality and the number of trophonts/juveniles were evaluated. In the second experiment, the antimicrobial potential in vitro (MIC test) and preventive potential in vivo against A. hydrophila was evaluated. The treatment with 1.5mgL(-1) NTZ showed the best result against Ich, with a significant reduction of trophonts and fish mortality of 10%. NTZ did not show in vitro activity against A. hydrophila at concentrations tested, but showed a probable preventive activity in vivo. However, these results are preliminary and more studies should be conducted. SN - 1873-2550 UR - https://www.unboundmedicine.com/medline/citation/23830481/The_use_of_nitazoxanide_against_the_pathogens_Ichthyophthirius_multifiliis_and_Aeromonas_hydrophila_in_silver_catfish__Rhamdia_quelen__ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0304-4017(13)00363-4 DB - PRIME DP - Unbound Medicine ER -