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Acute pancreatitis: a prospective study on incidence, etiology, and outcome.
Eur J Gastroenterol Hepatol. 2013 Sep; 25(9):1068-75.EJ

Abstract

BACKGROUND AND AIMS

Prospective and population-based studies on the incidence of acute pancreatitis (AP) are lacking. Alcohol consumption has increased considerably in Iceland during the last decade. We aimed to determine the incidence, etiology, severity, and complications of AP and compare the results with a previous study on AP in Iceland.

METHODS

A prospective population-based study of patients diagnosed with AP at the National University Hospital of Iceland during 1 year (2010-2011). Information on symptoms, etiology, and complications was registered.

RESULTS

During the study period, 134 patients were diagnosed with AP, 78 men (58%), median age 57 years (interquartile range 42-71). Overall, 89/104 (86%) patients had their first attack of pancreatitis, yielding a crude incidence of 40/100 000 inhabitants/year. The major etiological groups were as follows: gallstones, 52 cases (42%); alcohol 29, (23%); postendoscopic retrograde cholangio-pancreatography in 12 (9.5%); medications in eight (6.3%); and idiopathic in 15 (12%). Alcohol was more often the cause in men (25 vs. 4, P<0.05) but the incidence of gallstone-induced pancreatitis was similar in men and women (26 vs. 27). Seven patients had severe complications, three had pancreatic necrosis, two had pseudocysts, and one developed renal failure. Another patient developed acute respiratory distress syndrome and was admitted to the ICU. No patient died of AP during the study period.

CONCLUSION

The incidence of AP has not increased significantly in Iceland in the last decade. Alcohol-induced pancreatitis has not increased proportionally despite increased alcohol consumption in Iceland. In a population-based setting, the vast majority of AP is of mild severity.

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Authors+Show Affiliations

Vidarsdottir H
aDepartment of Anaesthesia and Intensive Care bDepartment of Surgery cDepartment of Gastroenterology, The National University Hospital of Iceland dFaculty of Medicine, University of Iceland, Reykjavik, Iceland eDepartment of Surgery, Helsingborg Hospital, Helsingborg, Sweden.
Möller PH
No affiliation info available
Vidarsdottir H
No affiliation info available
Thorarinsdottir H
No affiliation info available
Björnsson ES
No affiliation info available

MeSH

Acute DiseaseAdultAgedAged, 80 and overAlcohol DrinkingFemaleHospitals, UniversityHumansIcelandIncidenceMaleMiddle AgedPancreatic PseudocystPancreatitisPancreatitis, Acute NecrotizingPancreatitis, AlcoholicProspective StudiesRenal InsufficiencyRespiratory Distress SyndromeRisk FactorsSeverity of Illness IndexTime FactorsYoung Adult

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23839162

Citation

Vidarsdottir, Hanna, et al. "Acute Pancreatitis: a Prospective Study On Incidence, Etiology, and Outcome." European Journal of Gastroenterology & Hepatology, vol. 25, no. 9, 2013, pp. 1068-75.
Vidarsdottir H, Möller PH, Vidarsdottir H, et al. Acute pancreatitis: a prospective study on incidence, etiology, and outcome. Eur J Gastroenterol Hepatol. 2013;25(9):1068-75.
Vidarsdottir, H., Möller, P. H., Vidarsdottir, H., Thorarinsdottir, H., & Björnsson, E. S. (2013). Acute pancreatitis: a prospective study on incidence, etiology, and outcome. European Journal of Gastroenterology & Hepatology, 25(9), 1068-75. https://doi.org/10.1097/MEG.0b013e3283640fc8
Vidarsdottir H, et al. Acute Pancreatitis: a Prospective Study On Incidence, Etiology, and Outcome. Eur J Gastroenterol Hepatol. 2013;25(9):1068-75. PubMed PMID: 23839162.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute pancreatitis: a prospective study on incidence, etiology, and outcome. AU - Vidarsdottir,Hanna, AU - Möller,Pall H, AU - Vidarsdottir,Halla, AU - Thorarinsdottir,Hildur, AU - Björnsson,Einar S, PY - 2013/7/11/entrez PY - 2013/7/11/pubmed PY - 2014/8/5/medline SP - 1068 EP - 75 JF - European journal of gastroenterology & hepatology JO - Eur J Gastroenterol Hepatol VL - 25 IS - 9 N2 - BACKGROUND AND AIMS: Prospective and population-based studies on the incidence of acute pancreatitis (AP) are lacking. Alcohol consumption has increased considerably in Iceland during the last decade. We aimed to determine the incidence, etiology, severity, and complications of AP and compare the results with a previous study on AP in Iceland. METHODS: A prospective population-based study of patients diagnosed with AP at the National University Hospital of Iceland during 1 year (2010-2011). Information on symptoms, etiology, and complications was registered. RESULTS: During the study period, 134 patients were diagnosed with AP, 78 men (58%), median age 57 years (interquartile range 42-71). Overall, 89/104 (86%) patients had their first attack of pancreatitis, yielding a crude incidence of 40/100 000 inhabitants/year. The major etiological groups were as follows: gallstones, 52 cases (42%); alcohol 29, (23%); postendoscopic retrograde cholangio-pancreatography in 12 (9.5%); medications in eight (6.3%); and idiopathic in 15 (12%). Alcohol was more often the cause in men (25 vs. 4, P<0.05) but the incidence of gallstone-induced pancreatitis was similar in men and women (26 vs. 27). Seven patients had severe complications, three had pancreatic necrosis, two had pseudocysts, and one developed renal failure. Another patient developed acute respiratory distress syndrome and was admitted to the ICU. No patient died of AP during the study period. CONCLUSION: The incidence of AP has not increased significantly in Iceland in the last decade. Alcohol-induced pancreatitis has not increased proportionally despite increased alcohol consumption in Iceland. In a population-based setting, the vast majority of AP is of mild severity. SN - 1473-5687 UR - https://www.unboundmedicine.com/medline/citation/23839162/Acute_pancreatitis:_a_prospective_study_on_incidence_etiology_and_outcome_ L2 - https://doi.org/10.1097/MEG.0b013e3283640fc8 DB - PRIME DP - Unbound Medicine ER -