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Rickettsial infections in the tropics and in the traveler.
Curr Opin Infect Dis. 2013 Oct; 26(5):435-40.CO

Abstract

PURPOSE OF REVIEW

The purpose of this review is to describe recent advances in our understanding of the pathogenesis, epidemiology, and clinical features of rickettsial diseases with emphasis placed on those relating to travel and tropical medicine.

RECENT FINDINGS

Rickettsioses are becoming increasingly recognized as causes of febrile illness in travelers and in those residing in the tropics. In South and Central America, infection with Rickettsia rickettsii continues to have severe consequences. Resurgence of Mediterranean spotted fever in Bulgaria highlights the threat of rickettsial infections when there is a lapse in vector and reservoir control. Similar to African tick-bite fever, Rickettsia parkeri is an emerging cause of eschar-associated infection in Brazil, Argentina, and Uruguay. Several reports of murine typhus requiring hospitalization demonstrate the risk of this infection to the traveler. The use of fluoroquinolones for milder spotted fevers may fall out of favor with evidence of deleterious effects in those treated with ciprofloxacin.

SUMMARY

With globalization and increased access to travel, clinical awareness of rickettsial diseases is of increasing importance. Although the growing number of rickettsial species may be daunting to the clinician, recognition of the patterns of rickettsial disease will ensure prompt and effective therapy.

Authors+Show Affiliations

Division Infectious Diseases, Department of Internal Medicine, The University of Texas Medical Branch, Galveston, Texas, USA. lsblanto@utmb.edu

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23842049

Citation

Blanton, Lucas S.. "Rickettsial Infections in the Tropics and in the Traveler." Current Opinion in Infectious Diseases, vol. 26, no. 5, 2013, pp. 435-40.
Blanton LS. Rickettsial infections in the tropics and in the traveler. Curr Opin Infect Dis. 2013;26(5):435-40.
Blanton, L. S. (2013). Rickettsial infections in the tropics and in the traveler. Current Opinion in Infectious Diseases, 26(5), 435-40. https://doi.org/10.1097/QCO.0b013e328363811b
Blanton LS. Rickettsial Infections in the Tropics and in the Traveler. Curr Opin Infect Dis. 2013;26(5):435-40. PubMed PMID: 23842049.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rickettsial infections in the tropics and in the traveler. A1 - Blanton,Lucas S, PY - 2013/7/12/entrez PY - 2013/7/12/pubmed PY - 2014/3/7/medline SP - 435 EP - 40 JF - Current opinion in infectious diseases JO - Curr. Opin. Infect. Dis. VL - 26 IS - 5 N2 - PURPOSE OF REVIEW: The purpose of this review is to describe recent advances in our understanding of the pathogenesis, epidemiology, and clinical features of rickettsial diseases with emphasis placed on those relating to travel and tropical medicine. RECENT FINDINGS: Rickettsioses are becoming increasingly recognized as causes of febrile illness in travelers and in those residing in the tropics. In South and Central America, infection with Rickettsia rickettsii continues to have severe consequences. Resurgence of Mediterranean spotted fever in Bulgaria highlights the threat of rickettsial infections when there is a lapse in vector and reservoir control. Similar to African tick-bite fever, Rickettsia parkeri is an emerging cause of eschar-associated infection in Brazil, Argentina, and Uruguay. Several reports of murine typhus requiring hospitalization demonstrate the risk of this infection to the traveler. The use of fluoroquinolones for milder spotted fevers may fall out of favor with evidence of deleterious effects in those treated with ciprofloxacin. SUMMARY: With globalization and increased access to travel, clinical awareness of rickettsial diseases is of increasing importance. Although the growing number of rickettsial species may be daunting to the clinician, recognition of the patterns of rickettsial disease will ensure prompt and effective therapy. SN - 1473-6527 UR - https://www.unboundmedicine.com/medline/citation/23842049/Rickettsial_infections_in_the_tropics_and_in_the_traveler_ L2 - http://dx.doi.org/10.1097/QCO.0b013e328363811b DB - PRIME DP - Unbound Medicine ER -