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Acute cholecystitis from typhic origin in children.
Afr J Paediatr Surg. 2013 Apr-Jun; 10(2):108-11.AJ

Abstract

BACKGROUND

To evaluate the particularities of typhoid cholecystitis in children.

MATERIALS AND METHODS

This was a 5-year prospective study of typhoid cholecystitis in children under 15 years old at Djougou and Sylvanus Olympio teaching hospital. The diagnosis of typhoid cholecystitis was based on clinical and investigation findings, confirmed by operative findings at cholecystectomy.

RESULTS

Six children with typhoid acalculous cholecystitis were treated over a five-year period (4 males and 2 females). Their ages ranged from five to 13 years (median 8.8 years). The mean duration of symptoms was six to 21 days. The clinical signs were fever, abdominal pain, which predominated at the right upper abdominal quadrant, and type II Hackett splenomegaly. The diagnosis was confirmed by a positive Widal's test and Salmonella typhi isolation from the culture in all patients; four patients had ultrasound evidence of acalculous cholecystitis. Open cholecystectomy was successful in the six cases. The operative findings were gangrene (3), perforation (2) and empyema (1). All the patients made an uneventful recovery, and have remained symptom free one and three months on follow-up.

CONCLUSION

Typhoid acalculous cholecystitis is a frequent complication in children. Late presentation and diagnosis is associated with complications. Cholecystectomy in association with antibiotic is the treatment of choice.

Authors+Show Affiliations

Department of Pediatric Surgery, Sylvanus Olympio Teaching Hospital, Lomé-Togo, Togo.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study

Language

eng

PubMed ID

23860057

Citation

Gnassingbé, Komla, et al. "Acute Cholecystitis From Typhic Origin in Children." African Journal of Paediatric Surgery : AJPS, vol. 10, no. 2, 2013, pp. 108-11.
Gnassingbé K, Katakoa G, Kanassoua KK, et al. Acute cholecystitis from typhic origin in children. Afr J Paediatr Surg. 2013;10(2):108-11.
Gnassingbé, K., Katakoa, G., Kanassoua, K. K., Adabra, K., Mama, W. A., Simlawo, K., Eteh, K., & Tekou, H. (2013). Acute cholecystitis from typhic origin in children. African Journal of Paediatric Surgery : AJPS, 10(2), 108-11. https://doi.org/10.4103/0189-6725.115033
Gnassingbé K, et al. Acute Cholecystitis From Typhic Origin in Children. Afr J Paediatr Surg. 2013 Apr-Jun;10(2):108-11. PubMed PMID: 23860057.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute cholecystitis from typhic origin in children. AU - Gnassingbé,Komla, AU - Katakoa,Guissaga, AU - Kanassoua,Kokou K, AU - Adabra,Komla, AU - Mama,Wakatou A, AU - Simlawo,Kpatekana, AU - Eteh,Kossi, AU - Tekou,Hubert, PY - 2013/7/18/entrez PY - 2013/7/19/pubmed PY - 2014/3/19/medline SP - 108 EP - 11 JF - African journal of paediatric surgery : AJPS JO - Afr J Paediatr Surg VL - 10 IS - 2 N2 - BACKGROUND: To evaluate the particularities of typhoid cholecystitis in children. MATERIALS AND METHODS: This was a 5-year prospective study of typhoid cholecystitis in children under 15 years old at Djougou and Sylvanus Olympio teaching hospital. The diagnosis of typhoid cholecystitis was based on clinical and investigation findings, confirmed by operative findings at cholecystectomy. RESULTS: Six children with typhoid acalculous cholecystitis were treated over a five-year period (4 males and 2 females). Their ages ranged from five to 13 years (median 8.8 years). The mean duration of symptoms was six to 21 days. The clinical signs were fever, abdominal pain, which predominated at the right upper abdominal quadrant, and type II Hackett splenomegaly. The diagnosis was confirmed by a positive Widal's test and Salmonella typhi isolation from the culture in all patients; four patients had ultrasound evidence of acalculous cholecystitis. Open cholecystectomy was successful in the six cases. The operative findings were gangrene (3), perforation (2) and empyema (1). All the patients made an uneventful recovery, and have remained symptom free one and three months on follow-up. CONCLUSION: Typhoid acalculous cholecystitis is a frequent complication in children. Late presentation and diagnosis is associated with complications. Cholecystectomy in association with antibiotic is the treatment of choice. SN - 0974-5998 UR - https://www.unboundmedicine.com/medline/citation/23860057/Acute_cholecystitis_from_typhic_origin_in_children_ L2 - http://www.afrjpaedsurg.org/article.asp?issn=0189-6725;year=2013;volume=10;issue=2;spage=108;epage=111;aulast=Gnassingbé DB - PRIME DP - Unbound Medicine ER -