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Effect of glycerol on pressure difference between perilymph and endolymph.
Acta Otolaryngol. 1990 Jul-Aug; 110(1-2):68-72.AO

Abstract

The pressure difference between the perilymph and the endolymph following administration of 50% glycerol (12 ml/kg) was studied in guinea pigs. The perilymphatic and endolymphatic pressures were measured simultaneously with two sets of a servo-nulling system. Glycerol was administered for about one minute via a gastrocatheter. Both the perilymphatic and endolymphatic pressures began to decrease about 5 min after the administration of glycerol, and thereafter the decrease continued for about one hour with no significant difference between the two pressures. We concluded from the results that the glycerol-induced pressure difference between the perilymph and the endolymph, if present, is only a very small one, although a collapse of the scala media after glycerol intake was reported in guinea pigs and chinchillas.

Authors+Show Affiliations

Department of Otolaryngology, Kochi Medical School, Japan.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2386035

Citation

Takeda, T, et al. "Effect of Glycerol On Pressure Difference Between Perilymph and Endolymph." Acta Oto-laryngologica, vol. 110, no. 1-2, 1990, pp. 68-72.
Takeda T, Takeuchi S, Saito H. Effect of glycerol on pressure difference between perilymph and endolymph. Acta Otolaryngol. 1990;110(1-2):68-72.
Takeda, T., Takeuchi, S., & Saito, H. (1990). Effect of glycerol on pressure difference between perilymph and endolymph. Acta Oto-laryngologica, 110(1-2), 68-72.
Takeda T, Takeuchi S, Saito H. Effect of Glycerol On Pressure Difference Between Perilymph and Endolymph. Acta Otolaryngol. 1990 Jul-Aug;110(1-2):68-72. PubMed PMID: 2386035.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of glycerol on pressure difference between perilymph and endolymph. AU - Takeda,T, AU - Takeuchi,S, AU - Saito,H, PY - 1990/7/1/pubmed PY - 1990/7/1/medline PY - 1990/7/1/entrez SP - 68 EP - 72 JF - Acta oto-laryngologica JO - Acta Otolaryngol VL - 110 IS - 1-2 N2 - The pressure difference between the perilymph and the endolymph following administration of 50% glycerol (12 ml/kg) was studied in guinea pigs. The perilymphatic and endolymphatic pressures were measured simultaneously with two sets of a servo-nulling system. Glycerol was administered for about one minute via a gastrocatheter. Both the perilymphatic and endolymphatic pressures began to decrease about 5 min after the administration of glycerol, and thereafter the decrease continued for about one hour with no significant difference between the two pressures. We concluded from the results that the glycerol-induced pressure difference between the perilymph and the endolymph, if present, is only a very small one, although a collapse of the scala media after glycerol intake was reported in guinea pigs and chinchillas. SN - 0001-6489 UR - https://www.unboundmedicine.com/medline/citation/2386035/Effect_of_glycerol_on_pressure_difference_between_perilymph_and_endolymph_ L2 - https://www.tandfonline.com/doi/full/10.3109/00016489009122516 DB - PRIME DP - Unbound Medicine ER -