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Effect of short-term administration of cinnamon on blood pressure in patients with prediabetes and type 2 diabetes.
Nutrition. 2013 Oct; 29(10):1192-6.N

Abstract

OBJECTIVE

The aim of this study was to systematically review and evaluate the effect of short-term administration of cinnamon on blood pressure regulation in patients with prediabetes and type 2 diabetes by performing a meta-analysis of randomized, placebo-controlled clinical trials.

METHODS

Medical literature for randomized controlled trials (RCTs) of the effect of cinnamon on blood pressure was systematically searched; three original articles published between January 2000 and September 2012 were identified from the MEDLINE database and a hand search of the reference lists of the articles obtained through MEDLINE. The search terms included cinnamon or blood pressure or systolic blood pressure (SBP) or diastolic blood pressure (DBP) or diabetes. A random effects model was used to calculate weighted mean difference and 95% confidence intervals (CI).

RESULTS

The pooled estimate of the effect of cinnamon intake on SBP and DBP demonstrated that the use of cinnamon significantly decreased SBP and DBP by 5.39 mm Hg (95% CI, -6.89 to -3.89) and 2.6 mm Hg (95% CI, -4.53 to -0.66) respectively.

CONCLUSION

Consumption of cinnamon (short term) is associated with a notable reduction in SBP and DBP. Although cinnamon shows hopeful effects on BP-lowering potential, it would be premature to recommend cinnamon for BP control because of the limited number of studies available. Thus, undoubtedly a long-term, adequately powered RCT involving a larger number of patients is needed to appraise the clinical potential of cinnamon on BP control among patients with type 2 diabetes mellitus.

Authors+Show Affiliations

Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Ontario, Canada. rakilen22@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis
Review

Language

eng

PubMed ID

23867208

Citation

Akilen, Rajadurai, et al. "Effect of Short-term Administration of Cinnamon On Blood Pressure in Patients With Prediabetes and Type 2 Diabetes." Nutrition (Burbank, Los Angeles County, Calif.), vol. 29, no. 10, 2013, pp. 1192-6.
Akilen R, Pimlott Z, Tsiami A, et al. Effect of short-term administration of cinnamon on blood pressure in patients with prediabetes and type 2 diabetes. Nutrition. 2013;29(10):1192-6.
Akilen, R., Pimlott, Z., Tsiami, A., & Robinson, N. (2013). Effect of short-term administration of cinnamon on blood pressure in patients with prediabetes and type 2 diabetes. Nutrition (Burbank, Los Angeles County, Calif.), 29(10), 1192-6. https://doi.org/10.1016/j.nut.2013.03.007
Akilen R, et al. Effect of Short-term Administration of Cinnamon On Blood Pressure in Patients With Prediabetes and Type 2 Diabetes. Nutrition. 2013;29(10):1192-6. PubMed PMID: 23867208.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of short-term administration of cinnamon on blood pressure in patients with prediabetes and type 2 diabetes. AU - Akilen,Rajadurai, AU - Pimlott,Zeller, AU - Tsiami,Amalia, AU - Robinson,Nicola, Y1 - 2013/07/16/ PY - 2012/12/04/received PY - 2013/03/04/revised PY - 2013/03/06/accepted PY - 2013/7/23/entrez PY - 2013/7/23/pubmed PY - 2014/4/15/medline KW - Blood glucose KW - Blood pressure KW - Cinnamon KW - Diabetes KW - Randomized control trials SP - 1192 EP - 6 JF - Nutrition (Burbank, Los Angeles County, Calif.) JO - Nutrition VL - 29 IS - 10 N2 - OBJECTIVE: The aim of this study was to systematically review and evaluate the effect of short-term administration of cinnamon on blood pressure regulation in patients with prediabetes and type 2 diabetes by performing a meta-analysis of randomized, placebo-controlled clinical trials. METHODS: Medical literature for randomized controlled trials (RCTs) of the effect of cinnamon on blood pressure was systematically searched; three original articles published between January 2000 and September 2012 were identified from the MEDLINE database and a hand search of the reference lists of the articles obtained through MEDLINE. The search terms included cinnamon or blood pressure or systolic blood pressure (SBP) or diastolic blood pressure (DBP) or diabetes. A random effects model was used to calculate weighted mean difference and 95% confidence intervals (CI). RESULTS: The pooled estimate of the effect of cinnamon intake on SBP and DBP demonstrated that the use of cinnamon significantly decreased SBP and DBP by 5.39 mm Hg (95% CI, -6.89 to -3.89) and 2.6 mm Hg (95% CI, -4.53 to -0.66) respectively. CONCLUSION: Consumption of cinnamon (short term) is associated with a notable reduction in SBP and DBP. Although cinnamon shows hopeful effects on BP-lowering potential, it would be premature to recommend cinnamon for BP control because of the limited number of studies available. Thus, undoubtedly a long-term, adequately powered RCT involving a larger number of patients is needed to appraise the clinical potential of cinnamon on BP control among patients with type 2 diabetes mellitus. SN - 1873-1244 UR - https://www.unboundmedicine.com/medline/citation/23867208/Effect_of_short_term_administration_of_cinnamon_on_blood_pressure_in_patients_with_prediabetes_and_type_2_diabetes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0899-9007(13)00191-3 DB - PRIME DP - Unbound Medicine ER -