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Dietary phosphorus and kidney disease.
Ann N Y Acad Sci. 2013 Oct; 1301:11-9.AN

Abstract

High serum phosphate is linked to poor health outcome and mortality in chronic kidney disease (CKD) patients before or after the initiation of dialysis. Therefore, maintenance of normal serum phosphate levels is a major concern in the clinical care of this population with dietary phosphorus restriction and/or use of oral phosphate binders considered to be the best corrective care. This review discusses (1) evidence for an association between serum phosphate levels and bone and cardiovascular disease (CVD) in CKD patients as well as progression of kidney disease itself; (2) the relationship between serum phosphate and dietary phosphorus intake; and (3) implications from these data for future research. Increasing our understanding of the relationship between altered phosphorus metabolism and disease in CKD patients may clarify the potential role of excess dietary phosphorus as a risk factor for disease in the general population.

Authors+Show Affiliations

Department of Medicine, Mount Sinai School of Medicine, New York, New York.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23876096

Citation

Uribarri, Jaime. "Dietary Phosphorus and Kidney Disease." Annals of the New York Academy of Sciences, vol. 1301, 2013, pp. 11-9.
Uribarri J. Dietary phosphorus and kidney disease. Ann N Y Acad Sci. 2013;1301:11-9.
Uribarri, J. (2013). Dietary phosphorus and kidney disease. Annals of the New York Academy of Sciences, 1301, 11-9. https://doi.org/10.1111/nyas.12201
Uribarri J. Dietary Phosphorus and Kidney Disease. Ann N Y Acad Sci. 2013;1301:11-9. PubMed PMID: 23876096.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary phosphorus and kidney disease. A1 - Uribarri,Jaime, Y1 - 2013/07/22/ PY - 2013/7/24/entrez PY - 2013/7/24/pubmed PY - 2014/4/2/medline KW - atherosclerosis KW - bone disease KW - cardiovascular disease KW - chronic kidney disease KW - hyperparathyroidism KW - nutrition SP - 11 EP - 9 JF - Annals of the New York Academy of Sciences JO - Ann N Y Acad Sci VL - 1301 N2 - High serum phosphate is linked to poor health outcome and mortality in chronic kidney disease (CKD) patients before or after the initiation of dialysis. Therefore, maintenance of normal serum phosphate levels is a major concern in the clinical care of this population with dietary phosphorus restriction and/or use of oral phosphate binders considered to be the best corrective care. This review discusses (1) evidence for an association between serum phosphate levels and bone and cardiovascular disease (CVD) in CKD patients as well as progression of kidney disease itself; (2) the relationship between serum phosphate and dietary phosphorus intake; and (3) implications from these data for future research. Increasing our understanding of the relationship between altered phosphorus metabolism and disease in CKD patients may clarify the potential role of excess dietary phosphorus as a risk factor for disease in the general population. SN - 1749-6632 UR - https://www.unboundmedicine.com/medline/citation/23876096/Dietary_phosphorus_and_kidney_disease_ L2 - https://doi.org/10.1111/nyas.12201 DB - PRIME DP - Unbound Medicine ER -