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Effects of venovenous extracorporeal membrane oxygenation on cerebral oxygenation in hypercapnic ARDS.
Perfusion. 2014 Mar; 29(2):139-41.P

Abstract

Extracorporeal membrane oxygenation (ECMO) is increasingly used in ARDS patients with hypoxemia and/or severe hypercapnia refractory to conventional treatment strategies. However, it is associated with severe intracranial complications, e.g. ischemic or hemorrhagic stroke. The arterial carbon dioxide partial pressure (PaCO2) is one of the main determinants influencing cerebral blood flow and oxygenation. Since CO2 removal is highly effective during ECMO, reduction of CO2 may lead to alterations in cerebral perfusion. We report on the variations of cerebral oxygenation during the initiation period of ECMO treatment in a patient with hypercapnic ARDS, which may partly explain the findings of ischemic and/or hemorrhagic complications in conjunction with ECMO.

Authors+Show Affiliations

University of Würzburg, Würzburg, Germany.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

23887087

Citation

Muellenbach, R M., et al. "Effects of Venovenous Extracorporeal Membrane Oxygenation On Cerebral Oxygenation in Hypercapnic ARDS." Perfusion, vol. 29, no. 2, 2014, pp. 139-41.
Muellenbach RM, Kilgenstein C, Kranke P, et al. Effects of venovenous extracorporeal membrane oxygenation on cerebral oxygenation in hypercapnic ARDS. Perfusion. 2014;29(2):139-41.
Muellenbach, R. M., Kilgenstein, C., Kranke, P., Küstermann, J., Kredel, M., Roewer, N., Ernestus, R. I., & Westermaier, T. (2014). Effects of venovenous extracorporeal membrane oxygenation on cerebral oxygenation in hypercapnic ARDS. Perfusion, 29(2), 139-41. https://doi.org/10.1177/0267659113497073
Muellenbach RM, et al. Effects of Venovenous Extracorporeal Membrane Oxygenation On Cerebral Oxygenation in Hypercapnic ARDS. Perfusion. 2014;29(2):139-41. PubMed PMID: 23887087.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of venovenous extracorporeal membrane oxygenation on cerebral oxygenation in hypercapnic ARDS. AU - Muellenbach,R M, AU - Kilgenstein,C, AU - Kranke,P, AU - Küstermann,J, AU - Kredel,M, AU - Roewer,N, AU - Ernestus,R I, AU - Westermaier,T, Y1 - 2013/07/25/ PY - 2013/7/27/entrez PY - 2013/7/28/pubmed PY - 2014/10/16/medline KW - ARDS KW - ECMO KW - extracorporeal CO2 removal KW - interventional lung assist KW - near infrared spectroscopy SP - 139 EP - 41 JF - Perfusion JO - Perfusion VL - 29 IS - 2 N2 - Extracorporeal membrane oxygenation (ECMO) is increasingly used in ARDS patients with hypoxemia and/or severe hypercapnia refractory to conventional treatment strategies. However, it is associated with severe intracranial complications, e.g. ischemic or hemorrhagic stroke. The arterial carbon dioxide partial pressure (PaCO2) is one of the main determinants influencing cerebral blood flow and oxygenation. Since CO2 removal is highly effective during ECMO, reduction of CO2 may lead to alterations in cerebral perfusion. We report on the variations of cerebral oxygenation during the initiation period of ECMO treatment in a patient with hypercapnic ARDS, which may partly explain the findings of ischemic and/or hemorrhagic complications in conjunction with ECMO. SN - 1477-111X UR - https://www.unboundmedicine.com/medline/citation/23887087/Effects_of_venovenous_extracorporeal_membrane_oxygenation_on_cerebral_oxygenation_in_hypercapnic_ARDS_ L2 - https://journals.sagepub.com/doi/10.1177/0267659113497073?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -