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[Evaluation of various hemorheologic parameters in diabetes mellitus].
Boll Soc Ital Biol Sper. 1990 Apr; 66(4):335-42.BS

Abstract

It has been speculated that changes in intrinsic blood flow properties may contribute to the evolution of vascular complications in diabetes mellitus. To verify this hypothesis we measured hematocrit, fibrinogen, plasma and blood viscosity in 30 diabetic patients and in 25 healthy volunteers. Diabetics showed blood and plasma viscosity and fibrinogenemia higher than healthy subjects, although only plasma viscosity and fibrinogenemia were statistically significant (p less than 0.001). Moreover the diabetic patients with the highest HbAlc values had a significant increase in plasma viscosity compared with the patients with lower HbAlc values (p less than 0.001), despite a similar fibrinogenemia. This study confirms the presence of hemorheological changes in diabetes mellitus and shows a correlation between plasma viscosity and metabolic control.

Authors+Show Affiliations

Istituto Scientifico di Medicina Interna, Università degli Studi di Genova.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ita

PubMed ID

2390223

Citation

Cella, A, et al. "[Evaluation of Various Hemorheologic Parameters in Diabetes Mellitus]." Bollettino Della Societa Italiana Di Biologia Sperimentale, vol. 66, no. 4, 1990, pp. 335-42.
Cella A, Bianchi E, Reali GL, et al. [Evaluation of various hemorheologic parameters in diabetes mellitus]. Boll Soc Ital Biol Sper. 1990;66(4):335-42.
Cella, A., Bianchi, E., Reali, G. L., Piana, A., & Armani, U. (1990). [Evaluation of various hemorheologic parameters in diabetes mellitus]. Bollettino Della Societa Italiana Di Biologia Sperimentale, 66(4), 335-42.
Cella A, et al. [Evaluation of Various Hemorheologic Parameters in Diabetes Mellitus]. Boll Soc Ital Biol Sper. 1990;66(4):335-42. PubMed PMID: 2390223.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Evaluation of various hemorheologic parameters in diabetes mellitus]. AU - Cella,A, AU - Bianchi,E, AU - Reali,G L, AU - Piana,A, AU - Armani,U, PY - 1990/4/1/pubmed PY - 1990/4/1/medline PY - 1990/4/1/entrez SP - 335 EP - 42 JF - Bollettino della Societa italiana di biologia sperimentale JO - Boll. Soc. Ital. Biol. Sper. VL - 66 IS - 4 N2 - It has been speculated that changes in intrinsic blood flow properties may contribute to the evolution of vascular complications in diabetes mellitus. To verify this hypothesis we measured hematocrit, fibrinogen, plasma and blood viscosity in 30 diabetic patients and in 25 healthy volunteers. Diabetics showed blood and plasma viscosity and fibrinogenemia higher than healthy subjects, although only plasma viscosity and fibrinogenemia were statistically significant (p less than 0.001). Moreover the diabetic patients with the highest HbAlc values had a significant increase in plasma viscosity compared with the patients with lower HbAlc values (p less than 0.001), despite a similar fibrinogenemia. This study confirms the presence of hemorheological changes in diabetes mellitus and shows a correlation between plasma viscosity and metabolic control. SN - 0037-8771 UR - https://www.unboundmedicine.com/medline/citation/2390223/[Evaluation_of_various_hemorheologic_parameters_in_diabetes_mellitus]_ L2 - http://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -