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Erythrocyte and plasma magnesium in sickle-cell anaemia.
East Afr Med J 1990; 67(5):348-54EA

Abstract

Erythrocyte and plasma magnesium concentrations were measured in 168 subjects. Eighty three of the subjects were sickle-cell anaemia patients (sicklers) with haemoglobin genotype HbSS, and in the steady state; 30 were subjects who had the sickle-cell trait (HbAS), and 55 were subjects with the normal haemoglobin genotype HbAA. All the subjects were aged between 10 and 16 years. The sicklers had significantly lower erythrocyte (P less than 0.01) concentrations when compared with the normal subjects or subjects with the sickle-cell trait. Erythrocyte and plasma magnesium concentrations in subject with the sickle-cell trait were not significantly different from the corresponding values in the normal subjects. A significant negative correlation (r = -0.2661, P less than 0.02) was observed between erythrocyte magnesium and plasma magnesium in the sicklers only. However, magnesium concentrations in erythrocyte and plasma were not related to age, sex and physical stature in the three study groups. These results suggest that sickle-cell anaemia patients may be magnesium deficient.

Authors+Show Affiliations

Department of Chemical Pathology & Immunology, University of Ilorin Teaching Hospital, Kwara State, Nigeria.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2390957

Citation

Olukoga, A O., et al. "Erythrocyte and Plasma Magnesium in Sickle-cell Anaemia." East African Medical Journal, vol. 67, no. 5, 1990, pp. 348-54.
Olukoga AO, Adewoye HO, Erasmus RT, et al. Erythrocyte and plasma magnesium in sickle-cell anaemia. East Afr Med J. 1990;67(5):348-54.
Olukoga, A. O., Adewoye, H. O., Erasmus, R. T., & Adedoyin, M. A. (1990). Erythrocyte and plasma magnesium in sickle-cell anaemia. East African Medical Journal, 67(5), pp. 348-54.
Olukoga AO, et al. Erythrocyte and Plasma Magnesium in Sickle-cell Anaemia. East Afr Med J. 1990;67(5):348-54. PubMed PMID: 2390957.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Erythrocyte and plasma magnesium in sickle-cell anaemia. AU - Olukoga,A O, AU - Adewoye,H O, AU - Erasmus,R T, AU - Adedoyin,M A, PY - 1990/5/1/pubmed PY - 1990/5/1/medline PY - 1990/5/1/entrez SP - 348 EP - 54 JF - East African medical journal JO - East Afr Med J VL - 67 IS - 5 N2 - Erythrocyte and plasma magnesium concentrations were measured in 168 subjects. Eighty three of the subjects were sickle-cell anaemia patients (sicklers) with haemoglobin genotype HbSS, and in the steady state; 30 were subjects who had the sickle-cell trait (HbAS), and 55 were subjects with the normal haemoglobin genotype HbAA. All the subjects were aged between 10 and 16 years. The sicklers had significantly lower erythrocyte (P less than 0.01) concentrations when compared with the normal subjects or subjects with the sickle-cell trait. Erythrocyte and plasma magnesium concentrations in subject with the sickle-cell trait were not significantly different from the corresponding values in the normal subjects. A significant negative correlation (r = -0.2661, P less than 0.02) was observed between erythrocyte magnesium and plasma magnesium in the sicklers only. However, magnesium concentrations in erythrocyte and plasma were not related to age, sex and physical stature in the three study groups. These results suggest that sickle-cell anaemia patients may be magnesium deficient. SN - 0012-835X UR - https://www.unboundmedicine.com/medline/citation/2390957/Erythrocyte_and_plasma_magnesium_in_sickle_cell_anaemia_ DB - PRIME DP - Unbound Medicine ER -