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Evaluation of Albizia procera gum as compression coating material for colonic delivery of budesonide.
Int J Biol Macromol. 2013 Oct; 61:333-9.IJ

Abstract

The purpose of this research was to develop and evaluate Albizia procera gum as compression-coating polymer for colonic delivery of budesonide. Tablets were prepared by direct compression method using spray-dried lactose and microcrystalline cellulose as filler binders. The compatibility between the drug and the polymer was studied through TGA and FTIR spectroscopy. In vitro drug release were studied in dissolution media with or without 2% rat cecal contents while in vivo X-ray study was conducted on rabbits. The results indicate that procera gum and the drug were compatible with each other and tablet coated with procera gum was suitable for colonic delivery of drugs.

Authors+Show Affiliations

Department of Pharmaceutical Sciences, Dibrugarh University, Assam, 786004, India.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23916644

Citation

Pachuau, Lalduhsanga, and Bhaskar Mazumder. "Evaluation of Albizia Procera Gum as Compression Coating Material for Colonic Delivery of Budesonide." International Journal of Biological Macromolecules, vol. 61, 2013, pp. 333-9.
Pachuau L, Mazumder B. Evaluation of Albizia procera gum as compression coating material for colonic delivery of budesonide. Int J Biol Macromol. 2013;61:333-9.
Pachuau, L., & Mazumder, B. (2013). Evaluation of Albizia procera gum as compression coating material for colonic delivery of budesonide. International Journal of Biological Macromolecules, 61, 333-9. https://doi.org/10.1016/j.ijbiomac.2013.07.017
Pachuau L, Mazumder B. Evaluation of Albizia Procera Gum as Compression Coating Material for Colonic Delivery of Budesonide. Int J Biol Macromol. 2013;61:333-9. PubMed PMID: 23916644.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of Albizia procera gum as compression coating material for colonic delivery of budesonide. AU - Pachuau,Lalduhsanga, AU - Mazumder,Bhaskar, Y1 - 2013/08/02/ PY - 2013/05/28/received PY - 2013/07/06/revised PY - 2013/07/27/accepted PY - 2013/8/7/entrez PY - 2013/8/7/pubmed PY - 2014/5/9/medline KW - Albizia procera gum KW - Colon targeting KW - Compression-coated tablets SP - 333 EP - 9 JF - International journal of biological macromolecules JO - Int J Biol Macromol VL - 61 N2 - The purpose of this research was to develop and evaluate Albizia procera gum as compression-coating polymer for colonic delivery of budesonide. Tablets were prepared by direct compression method using spray-dried lactose and microcrystalline cellulose as filler binders. The compatibility between the drug and the polymer was studied through TGA and FTIR spectroscopy. In vitro drug release were studied in dissolution media with or without 2% rat cecal contents while in vivo X-ray study was conducted on rabbits. The results indicate that procera gum and the drug were compatible with each other and tablet coated with procera gum was suitable for colonic delivery of drugs. SN - 1879-0003 UR - https://www.unboundmedicine.com/medline/citation/23916644/Evaluation_of_Albizia_procera_gum_as_compression_coating_material_for_colonic_delivery_of_budesonide_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0141-8130(13)00413-3 DB - PRIME DP - Unbound Medicine ER -