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Prevalence of pharyngeal and rectal Chlamydia trachomatis and Neisseria gonorrhoeae infections among men who have sex with men in Germany.
Sex Transm Infect. 2014 Feb; 90(1):46-51.ST

Abstract

OBJECTIVES

To determine the prevalence of pharyngeal and rectal Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections among men who have sex with men (MSM) in Germany and describe associations between these infections, sexual practices and other factors to provide an evidence base for screening recommendations.

METHODS

We conducted a cross-sectional study in 22 sentinel sites of sexually transmitted infections across Germany. Pharyngeal and rectal swabs were collected and tested for CT and NG with a nucleic acid amplification test (NAAT). Information on HIV status, number of sex partners and sexual practices was collected and linked to NAAT results.

RESULTS

Overall, 2247 MSM were screened for pharyngeal or rectal CT and NG infections; median age was 34 years (range 16-83). Prevalence of CT was 1.5% in pharyngeal and 8.0% in rectal specimens. Prevalence of NG was 5.5% in pharyngeal and 4.6% in rectal specimens. Local symptoms were reported in 5.1% of pharyngeal and 11.9% of rectal infections. Altogether 90.8% of rectal or pharyngeal infections would remain undetected if only symptomatic cases were tested. Rectal infection was significantly more likely in men reporting multiple partners (2-5 partners, OR=1.85; 6-10 partners, OR=2.10; >11 partners, OR=2.95), men diagnosed with HIV (OR=1.60) and men practising receptive anal intercourse without a condom (OR=1.54). Pharyngeal infection was more likely in men reporting multiple partners (6-10 partners, OR=2.88; >11 partners, OR=4.96), and men diagnosed with HIV (OR=1.78).

CONCLUSIONS

Pharyngeal and rectal infections in sexually active MSM can remain undetected and thus transmissible if swabbing is not offered routinely. Screening should be offered particularly to MSM diagnosed with HIV and MSM reporting multiple partners.

Authors+Show Affiliations

HIV/AIDS, STI and Bloodborne Infections Unit, Department for Infectious Disease Epidemiology, Robert Koch Institute, , Berlin, Germany.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23920398

Citation

Dudareva-Vizule, Sandra, et al. "Prevalence of Pharyngeal and Rectal Chlamydia Trachomatis and Neisseria Gonorrhoeae Infections Among Men Who Have Sex With Men in Germany." Sexually Transmitted Infections, vol. 90, no. 1, 2014, pp. 46-51.
Dudareva-Vizule S, Haar K, Sailer A, et al. Prevalence of pharyngeal and rectal Chlamydia trachomatis and Neisseria gonorrhoeae infections among men who have sex with men in Germany. Sex Transm Infect. 2014;90(1):46-51.
Dudareva-Vizule, S., Haar, K., Sailer, A., Wisplinghoff, H., Wisplinghoff, F., & Marcus, U. (2014). Prevalence of pharyngeal and rectal Chlamydia trachomatis and Neisseria gonorrhoeae infections among men who have sex with men in Germany. Sexually Transmitted Infections, 90(1), 46-51. https://doi.org/10.1136/sextrans-2012-050929
Dudareva-Vizule S, et al. Prevalence of Pharyngeal and Rectal Chlamydia Trachomatis and Neisseria Gonorrhoeae Infections Among Men Who Have Sex With Men in Germany. Sex Transm Infect. 2014;90(1):46-51. PubMed PMID: 23920398.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of pharyngeal and rectal Chlamydia trachomatis and Neisseria gonorrhoeae infections among men who have sex with men in Germany. AU - Dudareva-Vizule,Sandra, AU - Haar,Karin, AU - Sailer,Andrea, AU - Wisplinghoff,Hilmar, AU - Wisplinghoff,Fabian, AU - Marcus,Ulrich, AU - ,, Y1 - 2013/08/06/ PY - 2013/8/8/entrez PY - 2013/8/8/pubmed PY - 2014/3/14/medline KW - EPIDEMIOLOGY (GENERAL) KW - HIV KW - INFECTION KW - SCREENING KW - SEXUAL HEALTH SP - 46 EP - 51 JF - Sexually transmitted infections JO - Sex Transm Infect VL - 90 IS - 1 N2 - OBJECTIVES: To determine the prevalence of pharyngeal and rectal Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections among men who have sex with men (MSM) in Germany and describe associations between these infections, sexual practices and other factors to provide an evidence base for screening recommendations. METHODS: We conducted a cross-sectional study in 22 sentinel sites of sexually transmitted infections across Germany. Pharyngeal and rectal swabs were collected and tested for CT and NG with a nucleic acid amplification test (NAAT). Information on HIV status, number of sex partners and sexual practices was collected and linked to NAAT results. RESULTS: Overall, 2247 MSM were screened for pharyngeal or rectal CT and NG infections; median age was 34 years (range 16-83). Prevalence of CT was 1.5% in pharyngeal and 8.0% in rectal specimens. Prevalence of NG was 5.5% in pharyngeal and 4.6% in rectal specimens. Local symptoms were reported in 5.1% of pharyngeal and 11.9% of rectal infections. Altogether 90.8% of rectal or pharyngeal infections would remain undetected if only symptomatic cases were tested. Rectal infection was significantly more likely in men reporting multiple partners (2-5 partners, OR=1.85; 6-10 partners, OR=2.10; >11 partners, OR=2.95), men diagnosed with HIV (OR=1.60) and men practising receptive anal intercourse without a condom (OR=1.54). Pharyngeal infection was more likely in men reporting multiple partners (6-10 partners, OR=2.88; >11 partners, OR=4.96), and men diagnosed with HIV (OR=1.78). CONCLUSIONS: Pharyngeal and rectal infections in sexually active MSM can remain undetected and thus transmissible if swabbing is not offered routinely. Screening should be offered particularly to MSM diagnosed with HIV and MSM reporting multiple partners. SN - 1472-3263 UR - https://www.unboundmedicine.com/medline/citation/23920398/Prevalence_of_pharyngeal_and_rectal_Chlamydia_trachomatis_and_Neisseria_gonorrhoeae_infections_among_men_who_have_sex_with_men_in_Germany_ L2 - https://sti.bmj.com/lookup/pmidlookup?view=long&pmid=23920398 DB - PRIME DP - Unbound Medicine ER -