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Prevalence and prognosis of congestive heart failure in Saudi patients admitted with acute coronary syndrome (from SPACE registry).
Coron Artery Dis. 2013 Nov; 24(7):596-601.CA

Abstract

OBJECTIVES

The aim of this study was to assess the prevalence, clinical features, and in-hospital outcomes of heart failure in patients with acute coronary syndrome (ACS).

MATERIALS AND METHODS

The Saudi Project for Assessment of Coronary Events recruited patients admitted with ACS from 17 hospitals in Saudi Arabia from 2005 to 2007. The outcomes of ACS patients with congestive heart failure (CHF) compared with those without CHF were analyzed.

RESULTS

A total of 4523 patients with ACS were identified, of whom 905 (20%) had CHF. Compared with no CHF, patients with CHF were older (62±13.1 vs. 57±12.9 years; P=0.001), less likely to be men (70 vs. 79%; P=0.001), likely to present with non-ST-segment elevation myocardial infarction (48 vs. 36%; P=0.001), likely to have diabetes (71 vs. 54%; P=0.001), hypertension (64 vs. 54%; P=0.001) and previous history of coronary artery disease (53 vs. 43%; P=0.001), and likely to have significant left ventricular systolic dysfunction (left ventricular ejection fraction <35%) (56 vs. 30%; P=0.001). Patients with CHF were less likely to receive in-hospital β-blockers (74 vs. 86%; P=0.001) and a percutaneous coronary intervention (19 vs. 50%; P=0.001). Adjusted in-hospital mortality and cardiogenic shock were higher in the CHF group (odds ratio 4.43, 95% confidence interval 2.52-7.78; and odds ratio 3.51, 95% confidence interval 2.23-5.52), respectively.

CONCLUSION

ACS patients with CHF in the Saudi Project for Assessment of Coronary Events were older, more likely to have more cardiac risk factors, and less likely to be treated with optimum medical treatment on admission. These findings were associated with higher incidence of their in-hospital adverse outcomes. More aggressive treatment is warranted to improve prognosis.

Authors+Show Affiliations

aKing Fahad Cardiac Center, College of Medicine, King Saud University bSecurity Forces Hospital cDepartment of Medicine, Prince Salman Heart Center, King Fahad Medical City, Riyadh dSaud Al-Babtain Cardiac Center, Dammam eKing Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Observational Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23928809

Citation

Albackr, Hanan B., et al. "Prevalence and Prognosis of Congestive Heart Failure in Saudi Patients Admitted With Acute Coronary Syndrome (from SPACE Registry)." Coronary Artery Disease, vol. 24, no. 7, 2013, pp. 596-601.
Albackr HB, Alhabib KF, Ullah A, et al. Prevalence and prognosis of congestive heart failure in Saudi patients admitted with acute coronary syndrome (from SPACE registry). Coron Artery Dis. 2013;24(7):596-601.
Albackr, H. B., Alhabib, K. F., Ullah, A., Alfaleh, H., Hersi, A., Alshaer, F., Alnemer, K., Al Saif, S., Taraben, A., & Kashour, T. (2013). Prevalence and prognosis of congestive heart failure in Saudi patients admitted with acute coronary syndrome (from SPACE registry). Coronary Artery Disease, 24(7), 596-601. https://doi.org/10.1097/MCA.0b013e328364d98f
Albackr HB, et al. Prevalence and Prognosis of Congestive Heart Failure in Saudi Patients Admitted With Acute Coronary Syndrome (from SPACE Registry). Coron Artery Dis. 2013;24(7):596-601. PubMed PMID: 23928809.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and prognosis of congestive heart failure in Saudi patients admitted with acute coronary syndrome (from SPACE registry). AU - Albackr,Hanan B, AU - Alhabib,Khalid F, AU - Ullah,Anhar, AU - Alfaleh,Hussam, AU - Hersi,Ahmad, AU - Alshaer,Fayez, AU - Alnemer,Khalid, AU - Al Saif,Shukri, AU - Taraben,Amir, AU - Kashour,Tarek, PY - 2013/8/10/entrez PY - 2013/8/10/pubmed PY - 2014/5/17/medline SP - 596 EP - 601 JF - Coronary artery disease JO - Coron. Artery Dis. VL - 24 IS - 7 N2 - OBJECTIVES: The aim of this study was to assess the prevalence, clinical features, and in-hospital outcomes of heart failure in patients with acute coronary syndrome (ACS). MATERIALS AND METHODS: The Saudi Project for Assessment of Coronary Events recruited patients admitted with ACS from 17 hospitals in Saudi Arabia from 2005 to 2007. The outcomes of ACS patients with congestive heart failure (CHF) compared with those without CHF were analyzed. RESULTS: A total of 4523 patients with ACS were identified, of whom 905 (20%) had CHF. Compared with no CHF, patients with CHF were older (62±13.1 vs. 57±12.9 years; P=0.001), less likely to be men (70 vs. 79%; P=0.001), likely to present with non-ST-segment elevation myocardial infarction (48 vs. 36%; P=0.001), likely to have diabetes (71 vs. 54%; P=0.001), hypertension (64 vs. 54%; P=0.001) and previous history of coronary artery disease (53 vs. 43%; P=0.001), and likely to have significant left ventricular systolic dysfunction (left ventricular ejection fraction <35%) (56 vs. 30%; P=0.001). Patients with CHF were less likely to receive in-hospital β-blockers (74 vs. 86%; P=0.001) and a percutaneous coronary intervention (19 vs. 50%; P=0.001). Adjusted in-hospital mortality and cardiogenic shock were higher in the CHF group (odds ratio 4.43, 95% confidence interval 2.52-7.78; and odds ratio 3.51, 95% confidence interval 2.23-5.52), respectively. CONCLUSION: ACS patients with CHF in the Saudi Project for Assessment of Coronary Events were older, more likely to have more cardiac risk factors, and less likely to be treated with optimum medical treatment on admission. These findings were associated with higher incidence of their in-hospital adverse outcomes. More aggressive treatment is warranted to improve prognosis. SN - 1473-5830 UR - https://www.unboundmedicine.com/medline/citation/23928809/Prevalence_and_prognosis_of_congestive_heart_failure_in_Saudi_patients_admitted_with_acute_coronary_syndrome__from_SPACE_registry__ L2 - http://dx.doi.org/10.1097/MCA.0b013e328364d98f DB - PRIME DP - Unbound Medicine ER -