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Fatty acid composition, physicochemical properties, antioxidant and cytotoxic activity of apple seed oil obtained from apple pomace.
J Sci Food Agric. 2014 Mar 30; 94(5):929-34.JS

Abstract

BACKGROUND

Apple pomace is generated in huge quantities in juice-processing industries the world over and continuous efforts are being made for its inclusive utilization. In this study, apple seeds separated from industrial pomace were used for extraction of oil. The fatty acid composition, physicochemical and antioxidant as well as in vitro anticancer properties of extracted oil were studied to assess its suitability in food and therapeutic applications.

RESULTS

The fatty acid composition of seed oil revealed the dominance of oleic (46.50%) and linoleic acid (43.81%). It had high iodine (121.8 g I 100 g⁻¹) and saponification value (184.91 mg KOH g⁻¹ oil). The acid value, refractive index and relative density were 4.28 mg KOH g⁻¹, 1.47 and 0.97 mg mL⁻¹, respectively. The antioxidant potential (IC₅₀) of apple seed oil was 40.06 µg mL⁻¹. Cytotoxicity of apple seed oil against CHOK1, SiHa and A549 cancer cell lines ranged between 0.5 ± 0.06% and 88.6 ± 0.3%.

CONCLUSION

The physicochemical properties of apple seed oil were comparable with edible food oil, indicating its better stability and broad application in the food and pharmaceutical industries. Apple seed oil could be a good source of natural antioxidants. Also, the in vitro cytotoxic activity against specific cell lines exhibited its potential as an anticancer agent.

Authors+Show Affiliations

Academy of Scientific and Innovative Research, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176061, India; Natural Plant Products Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh, 176061, India.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23929365

Citation

Walia, Mayanka, et al. "Fatty Acid Composition, Physicochemical Properties, Antioxidant and Cytotoxic Activity of Apple Seed Oil Obtained From Apple Pomace." Journal of the Science of Food and Agriculture, vol. 94, no. 5, 2014, pp. 929-34.
Walia M, Rawat K, Bhushan S, et al. Fatty acid composition, physicochemical properties, antioxidant and cytotoxic activity of apple seed oil obtained from apple pomace. J Sci Food Agric. 2014;94(5):929-34.
Walia, M., Rawat, K., Bhushan, S., Padwad, Y. S., & Singh, B. (2014). Fatty acid composition, physicochemical properties, antioxidant and cytotoxic activity of apple seed oil obtained from apple pomace. Journal of the Science of Food and Agriculture, 94(5), 929-34. https://doi.org/10.1002/jsfa.6337
Walia M, et al. Fatty Acid Composition, Physicochemical Properties, Antioxidant and Cytotoxic Activity of Apple Seed Oil Obtained From Apple Pomace. J Sci Food Agric. 2014 Mar 30;94(5):929-34. PubMed PMID: 23929365.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fatty acid composition, physicochemical properties, antioxidant and cytotoxic activity of apple seed oil obtained from apple pomace. AU - Walia,Mayanka, AU - Rawat,Kiran, AU - Bhushan,Shashi, AU - Padwad,Yogendra S, AU - Singh,Bikram, Y1 - 2013/09/04/ PY - 2013/05/17/received PY - 2013/07/17/revised PY - 2013/08/08/accepted PY - 2013/8/10/entrez PY - 2013/8/10/pubmed PY - 2014/12/17/medline KW - apple seed oil KW - cytotoxicity KW - linoleic acid KW - oleic acid KW - palmitic acid KW - physiochemical properties SP - 929 EP - 34 JF - Journal of the science of food and agriculture JO - J Sci Food Agric VL - 94 IS - 5 N2 - BACKGROUND: Apple pomace is generated in huge quantities in juice-processing industries the world over and continuous efforts are being made for its inclusive utilization. In this study, apple seeds separated from industrial pomace were used for extraction of oil. The fatty acid composition, physicochemical and antioxidant as well as in vitro anticancer properties of extracted oil were studied to assess its suitability in food and therapeutic applications. RESULTS: The fatty acid composition of seed oil revealed the dominance of oleic (46.50%) and linoleic acid (43.81%). It had high iodine (121.8 g I 100 g⁻¹) and saponification value (184.91 mg KOH g⁻¹ oil). The acid value, refractive index and relative density were 4.28 mg KOH g⁻¹, 1.47 and 0.97 mg mL⁻¹, respectively. The antioxidant potential (IC₅₀) of apple seed oil was 40.06 µg mL⁻¹. Cytotoxicity of apple seed oil against CHOK1, SiHa and A549 cancer cell lines ranged between 0.5 ± 0.06% and 88.6 ± 0.3%. CONCLUSION: The physicochemical properties of apple seed oil were comparable with edible food oil, indicating its better stability and broad application in the food and pharmaceutical industries. Apple seed oil could be a good source of natural antioxidants. Also, the in vitro cytotoxic activity against specific cell lines exhibited its potential as an anticancer agent. SN - 1097-0010 UR - https://www.unboundmedicine.com/medline/citation/23929365/Fatty_acid_composition_physicochemical_properties_antioxidant_and_cytotoxic_activity_of_apple_seed_oil_obtained_from_apple_pomace_ L2 - https://doi.org/10.1002/jsfa.6337 DB - PRIME DP - Unbound Medicine ER -