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[Thrombocytopenia during pregnancy].

Abstract

Thrombocytopenia during pregnancy can be caused by a broad variety of disorders. An early diagnosis is essential for timely and adequate therapy. In cases of severe thrombocytopenia, a multidisciplinary approach by a team of obstetricians, haematologists and anaesthesiologists is needed. We describe a 30-year-old patient at a gestational age of 35 weeks who presented with preterm rupture of membranes. Coincidentally, she also had severe thrombocytopenia that proved to be due to immune thrombocytopenia (ITP). The severe thrombocytopenia persisted despite standard first-line treatment with corticosteroids and intravenous immunoglobulins. Based on this case report we discuss the differential diagnosis of thrombocytopenia during pregnancy with a focus on the management of ITP in pregnant women.

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  • Authors+Show Affiliations

    ,

    Erasmus Medisch Centrum, Rotterdam.

    , , , ,

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    MeSH

    Adrenal Cortex Hormones
    Adult
    Female
    Fetal Membranes, Premature Rupture
    Humans
    Immunoglobulins
    Obstetric Labor, Premature
    Platelet Count
    Pregnancy
    Pregnancy Complications, Hematologic
    Pregnancy Outcome
    Prenatal Care
    Thrombocytopenia

    Pub Type(s)

    Journal Article

    Language

    dut

    PubMed ID

    23945435

    Citation

    Rokx, C, et al. "[Thrombocytopenia During Pregnancy]." Nederlands Tijdschrift Voor Geneeskunde, vol. 157, no. 33, 2013, pp. A6445.
    Rokx C, Swart RM, van Houten AA, et al. [Thrombocytopenia during pregnancy]. Ned Tijdschr Geneeskd. 2013;157(33):A6445.
    Rokx, C., Swart, R. M., van Houten, A. A., Leys, M. B., Duvekot, J. J., & Te Boekhorst, P. A. (2013). [Thrombocytopenia during pregnancy]. Nederlands Tijdschrift Voor Geneeskunde, 157(33), pp. A6445.
    Rokx C, et al. [Thrombocytopenia During Pregnancy]. Ned Tijdschr Geneeskd. 2013;157(33):A6445. PubMed PMID: 23945435.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - [Thrombocytopenia during pregnancy]. AU - Rokx,C, AU - Swart,R M, AU - van Houten,A A, AU - Leys,M B, AU - Duvekot,J J, AU - Te Boekhorst,P A W, PY - 2013/8/16/entrez PY - 2013/8/16/pubmed PY - 2014/4/17/medline SP - A6445 EP - A6445 JF - Nederlands tijdschrift voor geneeskunde JO - Ned Tijdschr Geneeskd VL - 157 IS - 33 N2 - Thrombocytopenia during pregnancy can be caused by a broad variety of disorders. An early diagnosis is essential for timely and adequate therapy. In cases of severe thrombocytopenia, a multidisciplinary approach by a team of obstetricians, haematologists and anaesthesiologists is needed. We describe a 30-year-old patient at a gestational age of 35 weeks who presented with preterm rupture of membranes. Coincidentally, she also had severe thrombocytopenia that proved to be due to immune thrombocytopenia (ITP). The severe thrombocytopenia persisted despite standard first-line treatment with corticosteroids and intravenous immunoglobulins. Based on this case report we discuss the differential diagnosis of thrombocytopenia during pregnancy with a focus on the management of ITP in pregnant women. SN - 1876-8784 UR - https://www.unboundmedicine.com/medline/citation/23945435/[Thrombocytopenia_during_pregnancy]_ L2 - http://www.ntvg.nl/A6445 DB - PRIME DP - Unbound Medicine ER -