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Ultrasensitive photoelectrochemical immunoassay of indole-3-acetic acid based on the MPA modified CdS/RGO nanocomposites decorated ITO electrode.
Biosens Bioelectron. 2014 Jan 15; 51:164-9.BB

Abstract

A novel ultrasensitive photoelectrochemical immunosensor was fabricated based on 3-mercaptopropionic acid stabilized CdS/reduced graphene oxide (MPA-CdS/RGO) nanocomposites for indole-3-acetic acid (IAA) detection. The MPA-CdS/RGO nanocomposites were synthesized by in situ solvothermal growth of triangulated pyramidal CdS nanoparticles on the RGO sheet. 3-Mercaptopropionic acid (MPA) was employed as the modifier and bridge to immobilize the antibody. The nanocomposites were characterized by X-ray diffraction, transmission electron microscopy, scanning electron microscopy and UV/vis spectra. The results showed that the MPA-CdS/RGO nanocomposites revealed enhanced photocurrent response due to excellent electron transport properties of RGO and the improved assembly of CdS nanoparticles onto RGO sheet with the introduction of MPA. Based on the dependence of the photocurrent decline on the concentration of IAA, the proposed photoelectrochemical immunosensor for IAA depicted a linear range from 0.1 to 1000 ng/mL with a lower detection limit (0.05 ng/mL). The high sensitivity, reproducibility and specificity of the method permitted the method suitable to be used in real samples.

Authors+Show Affiliations

College of Chemistry and Material Science, Shandong Agricultural University, Taian 271018, PR China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23954674

Citation

Sun, Bing, et al. "Ultrasensitive Photoelectrochemical Immunoassay of Indole-3-acetic Acid Based On the MPA Modified CdS/RGO Nanocomposites Decorated ITO Electrode." Biosensors & Bioelectronics, vol. 51, 2014, pp. 164-9.
Sun B, Chen L, Xu Y, et al. Ultrasensitive photoelectrochemical immunoassay of indole-3-acetic acid based on the MPA modified CdS/RGO nanocomposites decorated ITO electrode. Biosens Bioelectron. 2014;51:164-9.
Sun, B., Chen, L., Xu, Y., Liu, M., Yin, H., & Ai, S. (2014). Ultrasensitive photoelectrochemical immunoassay of indole-3-acetic acid based on the MPA modified CdS/RGO nanocomposites decorated ITO electrode. Biosensors & Bioelectronics, 51, 164-9. https://doi.org/10.1016/j.bios.2013.07.027
Sun B, et al. Ultrasensitive Photoelectrochemical Immunoassay of Indole-3-acetic Acid Based On the MPA Modified CdS/RGO Nanocomposites Decorated ITO Electrode. Biosens Bioelectron. 2014 Jan 15;51:164-9. PubMed PMID: 23954674.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ultrasensitive photoelectrochemical immunoassay of indole-3-acetic acid based on the MPA modified CdS/RGO nanocomposites decorated ITO electrode. AU - Sun,Bing, AU - Chen,Lijian, AU - Xu,Yan, AU - Liu,Min, AU - Yin,Huanshun, AU - Ai,Shiyun, Y1 - 2013/07/18/ PY - 2013/04/21/received PY - 2013/07/10/revised PY - 2013/07/11/accepted PY - 2013/8/20/entrez PY - 2013/8/21/pubmed PY - 2014/5/13/medline KW - 3-Mercaptopropionic acid KW - Cadmium sulfides KW - Indole-3-acetic acid KW - Photoelectrochemical immunosensor KW - Reduced graphene oxide SP - 164 EP - 9 JF - Biosensors & bioelectronics JO - Biosens Bioelectron VL - 51 N2 - A novel ultrasensitive photoelectrochemical immunosensor was fabricated based on 3-mercaptopropionic acid stabilized CdS/reduced graphene oxide (MPA-CdS/RGO) nanocomposites for indole-3-acetic acid (IAA) detection. The MPA-CdS/RGO nanocomposites were synthesized by in situ solvothermal growth of triangulated pyramidal CdS nanoparticles on the RGO sheet. 3-Mercaptopropionic acid (MPA) was employed as the modifier and bridge to immobilize the antibody. The nanocomposites were characterized by X-ray diffraction, transmission electron microscopy, scanning electron microscopy and UV/vis spectra. The results showed that the MPA-CdS/RGO nanocomposites revealed enhanced photocurrent response due to excellent electron transport properties of RGO and the improved assembly of CdS nanoparticles onto RGO sheet with the introduction of MPA. Based on the dependence of the photocurrent decline on the concentration of IAA, the proposed photoelectrochemical immunosensor for IAA depicted a linear range from 0.1 to 1000 ng/mL with a lower detection limit (0.05 ng/mL). The high sensitivity, reproducibility and specificity of the method permitted the method suitable to be used in real samples. SN - 1873-4235 UR - https://www.unboundmedicine.com/medline/citation/23954674/Ultrasensitive_photoelectrochemical_immunoassay_of_indole_3_acetic_acid_based_on_the_MPA_modified_CdS/RGO_nanocomposites_decorated_ITO_electrode_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0956-5663(13)00499-5 DB - PRIME DP - Unbound Medicine ER -