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Prominent follicular mucinosis with diffuse scalp alopecia resembling alopecia areata.
J Cutan Pathol. 2013 Oct; 40(10):887-90.JC

Abstract

A 56-year-old Caucasian female presented with a 2-month history of alopecia. On examination, she had diffuse hair loss of her scalp with some discrete patches of nonscarring alopecia. Histopathology revealed an inflammatory nonscarring alopecia with prominent follicular mucinosis and findings suggestive of alopecia areata. The patient's alopecia completely resolved with oral prednisone. The histopathologic findings and clinical presentation are most consistent with a diagnosis of alopecia areata with follicular mucinosis, although the differential diagnosis is broad. As follicular mucinosis may be associated with both benign and malignant conditions, it is important to be cautious regarding the clinical diagnosis when this reaction pattern is observed histopathologically.

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Authors+Show Affiliations

Missall TA
Department of Dermatology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Hurley MY
No affiliation info available
Burkemper NM
No affiliation info available

MeSH

Alopecia AreataAnti-Inflammatory AgentsDiagnosis, DifferentialFemaleHumansMiddle AgedMucinosis, FollicularPrednisoneScalp

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23962142

Citation

Missall, Tricia A., et al. "Prominent Follicular Mucinosis With Diffuse Scalp Alopecia Resembling Alopecia Areata." Journal of Cutaneous Pathology, vol. 40, no. 10, 2013, pp. 887-90.
Missall TA, Hurley MY, Burkemper NM. Prominent follicular mucinosis with diffuse scalp alopecia resembling alopecia areata. J Cutan Pathol. 2013;40(10):887-90.
Missall, T. A., Hurley, M. Y., & Burkemper, N. M. (2013). Prominent follicular mucinosis with diffuse scalp alopecia resembling alopecia areata. Journal of Cutaneous Pathology, 40(10), 887-90. https://doi.org/10.1111/cup.12201
Missall TA, Hurley MY, Burkemper NM. Prominent Follicular Mucinosis With Diffuse Scalp Alopecia Resembling Alopecia Areata. J Cutan Pathol. 2013;40(10):887-90. PubMed PMID: 23962142.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prominent follicular mucinosis with diffuse scalp alopecia resembling alopecia areata. AU - Missall,Tricia A, AU - Hurley,M Yadira, AU - Burkemper,Nicole M, Y1 - 2013/08/21/ PY - 2013/03/01/received PY - 2013/06/12/revised PY - 2013/06/24/accepted PY - 2013/8/22/entrez PY - 2013/8/22/pubmed PY - 2014/4/26/medline KW - alopecia areata KW - alopecia mucinosa KW - follicular mucinosis SP - 887 EP - 90 JF - Journal of cutaneous pathology JO - J Cutan Pathol VL - 40 IS - 10 N2 - A 56-year-old Caucasian female presented with a 2-month history of alopecia. On examination, she had diffuse hair loss of her scalp with some discrete patches of nonscarring alopecia. Histopathology revealed an inflammatory nonscarring alopecia with prominent follicular mucinosis and findings suggestive of alopecia areata. The patient's alopecia completely resolved with oral prednisone. The histopathologic findings and clinical presentation are most consistent with a diagnosis of alopecia areata with follicular mucinosis, although the differential diagnosis is broad. As follicular mucinosis may be associated with both benign and malignant conditions, it is important to be cautious regarding the clinical diagnosis when this reaction pattern is observed histopathologically. SN - 1600-0560 UR - https://www.unboundmedicine.com/medline/citation/23962142/Prominent_follicular_mucinosis_with_diffuse_scalp_alopecia_resembling_alopecia_areata_ L2 - https://doi.org/10.1111/cup.12201 DB - PRIME DP - Unbound Medicine ER -