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Vesicular syphilid in a seropositive patient.
Int J STD AIDS. 2013 Nov; 24(11):905-7.IJ

Abstract

Syphilis is a sexually transmitted infection with various stages of evolution and a myriad of presentations. To avoid a delay in diagnosis, it is important to recognize secondary syphilis presenting with vesicular lesions. A patient presented with maculopapular rash of recent onset with several vesicles and related the eruption to paracetamol taken one day before. The differential diagnoses considered were drug eruption, pityriasis lichenoides et varioliformis acuta, pityriasis rosea and secondary syphilis. HIV, VDRL (1:256) and TPHA tests were positive and histopathology revealed lymphohistiocytic infiltrate and plasma cells. Thus, a diagnosis of secondary syphilis coexisting with HIV was confirmed. The patient was administered benzathine penicillin and anti-retroviral therapy was started. He responded very well to treatment. We report this case because of the rarity of vesicular eruption in secondary syphilis.

Authors+Show Affiliations

Department of Dermatology & Venereology, ESIC-PGIMSR, Basaidarapur, New Delhi, India.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

23970637

Citation

Arora, Shikha, et al. "Vesicular Syphilid in a Seropositive Patient." International Journal of STD & AIDS, vol. 24, no. 11, 2013, pp. 905-7.
Arora S, Dhali TK, Haroon MA. Vesicular syphilid in a seropositive patient. Int J STD AIDS. 2013;24(11):905-7.
Arora, S., Dhali, T. K., & Haroon, M. A. (2013). Vesicular syphilid in a seropositive patient. International Journal of STD & AIDS, 24(11), 905-7. https://doi.org/10.1177/0956462413495382
Arora S, Dhali TK, Haroon MA. Vesicular Syphilid in a Seropositive Patient. Int J STD AIDS. 2013;24(11):905-7. PubMed PMID: 23970637.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vesicular syphilid in a seropositive patient. AU - Arora,Shikha, AU - Dhali,Tapan K, AU - Haroon,Mohammad A, Y1 - 2013/07/19/ PY - 2013/8/24/entrez PY - 2013/8/24/pubmed PY - 2014/2/19/medline KW - AIDS KW - HIV KW - Syphilis (Treponema pallidum) KW - maculopapular rash KW - secondary syphilis KW - vesicular syphilid SP - 905 EP - 7 JF - International journal of STD & AIDS JO - Int J STD AIDS VL - 24 IS - 11 N2 - Syphilis is a sexually transmitted infection with various stages of evolution and a myriad of presentations. To avoid a delay in diagnosis, it is important to recognize secondary syphilis presenting with vesicular lesions. A patient presented with maculopapular rash of recent onset with several vesicles and related the eruption to paracetamol taken one day before. The differential diagnoses considered were drug eruption, pityriasis lichenoides et varioliformis acuta, pityriasis rosea and secondary syphilis. HIV, VDRL (1:256) and TPHA tests were positive and histopathology revealed lymphohistiocytic infiltrate and plasma cells. Thus, a diagnosis of secondary syphilis coexisting with HIV was confirmed. The patient was administered benzathine penicillin and anti-retroviral therapy was started. He responded very well to treatment. We report this case because of the rarity of vesicular eruption in secondary syphilis. SN - 1758-1052 UR - https://www.unboundmedicine.com/medline/citation/23970637/Vesicular_syphilid_in_a_seropositive_patient_ L2 - https://journals.sagepub.com/doi/10.1177/0956462413495382?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -