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Selenium and the thyroid.

Abstract

PURPOSE OF REVIEW

To provide information on the role of the essential trace element selenium, which enables appropriate thyroid hormone synthesis, secretion, and metabolism, and to discuss supplementation with various selenium compounds, which prevent thyroid diseases such as goiter and exert beneficial effects in thyroid autoimmune diseases.

RECENT FINDINGS

Selenium administration in both autoimmune thyroiditis (M. Hashimoto) and mild Graves' disease improves clinical scores and well-being of patients and reduces autoimmune antibody titres in several prospective, placebo-controlled supplementation studies.

SUMMARY

Adequate nutritional supply of selenium, together with the two other essential trace elements iodine and iron, is required for a healthy thyroid during development and adolescence, as well as in the adult and aging populations.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    Institute of Experimental Endocrinology, Charité University Medicine Berlin, Germany. josef.koehrle@charite.de

    Source

    MeSH

    Adult
    Animals
    Congenital Hypothyroidism
    Humans
    Iodide Peroxidase
    Myxedema
    Oxidative Stress
    Selenium
    Selenoproteins
    Thyroid Gland

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    23974773

    Citation

    Köhrle, Josef. "Selenium and the Thyroid." Current Opinion in Endocrinology, Diabetes, and Obesity, vol. 20, no. 5, 2013, pp. 441-8.
    Köhrle J. Selenium and the thyroid. Curr Opin Endocrinol Diabetes Obes. 2013;20(5):441-8.
    Köhrle, J. (2013). Selenium and the thyroid. Current Opinion in Endocrinology, Diabetes, and Obesity, 20(5), pp. 441-8. doi:10.1097/01.med.0000433066.24541.88.
    Köhrle J. Selenium and the Thyroid. Curr Opin Endocrinol Diabetes Obes. 2013;20(5):441-8. PubMed PMID: 23974773.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Selenium and the thyroid. A1 - Köhrle,Josef, PY - 2013/8/27/entrez PY - 2013/8/27/pubmed PY - 2014/4/1/medline SP - 441 EP - 8 JF - Current opinion in endocrinology, diabetes, and obesity JO - Curr Opin Endocrinol Diabetes Obes VL - 20 IS - 5 N2 - PURPOSE OF REVIEW: To provide information on the role of the essential trace element selenium, which enables appropriate thyroid hormone synthesis, secretion, and metabolism, and to discuss supplementation with various selenium compounds, which prevent thyroid diseases such as goiter and exert beneficial effects in thyroid autoimmune diseases. RECENT FINDINGS: Selenium administration in both autoimmune thyroiditis (M. Hashimoto) and mild Graves' disease improves clinical scores and well-being of patients and reduces autoimmune antibody titres in several prospective, placebo-controlled supplementation studies. SUMMARY: Adequate nutritional supply of selenium, together with the two other essential trace elements iodine and iron, is required for a healthy thyroid during development and adolescence, as well as in the adult and aging populations. SN - 1752-2978 UR - https://www.unboundmedicine.com/medline/citation/23974773/Selenium_and_the_thyroid_ L2 - http://Insights.ovid.com/pubmed?pmid=23974773 DB - PRIME DP - Unbound Medicine ER -