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The biological effects of a pulsed electrostatic field with specific reference to hair. Electrotrichogenesis.
Int J Dermatol 1990 Jul-Aug; 29(6):446-50IJ

Abstract

This comparative, controlled study demonstrates the positive biologic effect on hair regrowth of a pulsed electrical field administered according to a regularized treatment schedule over 36 weeks. Mean hair count comparisons within the groups significantly favor the treatment group, which exhibited a 66.1% hair count increase over baseline. The control group increase over baseline was 25.6%. It is notable also that 29 of the 30 treatment subjects (96.7%) exhibited regrowth or no further hair loss. The process is without side effects and untoward reactions. The rationale of this phenomenon is unclear but is considered to be due to an electrophysiologic effect on the quiescent hair follicle, similar to that documented with respect to bone fracture and soft tissue repair enhancement. The electrical pulse may cause increased cell mitosis through calcium influx, involving both the hair follicle sheath and dermal papilla cells.

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  • Publisher Full Text

    • Authors+Show Affiliations

    Maddin WS
    Division of Dermatology, University of British Columbia School of Medicine, Vancouver, Canada.
    Bell PW
    No affiliation info available
    James JH
    No affiliation info available

    MeSH

    AdultAlopeciaElectric Stimulation TherapyElectricityEquipment DesignFollow-Up StudiesHairHumansMaleMiddle AgedProbabilityRandom AllocationSingle-Blind MethodTime Factors

    Pub Type(s)

    Clinical Trial
    Controlled Clinical Trial
    Journal Article
    Randomized Controlled Trial
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    2397975

    Citation

    Maddin, W S., et al. "The Biological Effects of a Pulsed Electrostatic Field With Specific Reference to Hair. Electrotrichogenesis." International Journal of Dermatology, vol. 29, no. 6, 1990, pp. 446-50.
    Maddin WS, Bell PW, James JH. The biological effects of a pulsed electrostatic field with specific reference to hair. Electrotrichogenesis. Int J Dermatol. 1990;29(6):446-50.
    Maddin, W. S., Bell, P. W., & James, J. H. (1990). The biological effects of a pulsed electrostatic field with specific reference to hair. Electrotrichogenesis. International Journal of Dermatology, 29(6), pp. 446-50.
    Maddin WS, Bell PW, James JH. The Biological Effects of a Pulsed Electrostatic Field With Specific Reference to Hair. Electrotrichogenesis. Int J Dermatol. 1990;29(6):446-50. PubMed PMID: 2397975.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - The biological effects of a pulsed electrostatic field with specific reference to hair. Electrotrichogenesis. AU - Maddin,W S, AU - Bell,P W, AU - James,J H, PY - 1990/7/1/pubmed PY - 1990/7/1/medline PY - 1990/7/1/entrez SP - 446 EP - 50 JF - International journal of dermatology JO - Int. J. Dermatol. VL - 29 IS - 6 N2 - This comparative, controlled study demonstrates the positive biologic effect on hair regrowth of a pulsed electrical field administered according to a regularized treatment schedule over 36 weeks. Mean hair count comparisons within the groups significantly favor the treatment group, which exhibited a 66.1% hair count increase over baseline. The control group increase over baseline was 25.6%. It is notable also that 29 of the 30 treatment subjects (96.7%) exhibited regrowth or no further hair loss. The process is without side effects and untoward reactions. The rationale of this phenomenon is unclear but is considered to be due to an electrophysiologic effect on the quiescent hair follicle, similar to that documented with respect to bone fracture and soft tissue repair enhancement. The electrical pulse may cause increased cell mitosis through calcium influx, involving both the hair follicle sheath and dermal papilla cells. SN - 0011-9059 UR - https://www.unboundmedicine.com/medline/citation/2397975/The_biological_effects_of_a_pulsed_electrostatic_field_with_specific_reference_to_hair__Electrotrichogenesis_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0011-9059&date=1990&volume=29&issue=6&spage=446 DB - PRIME DP - Unbound Medicine ER -