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The role of omega-3 polyunsaturated fatty acids in cardiovascular health.
Altern Ther Health Med. 2013; 19 Suppl 1:26-30.AT

Abstract

Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) play an important role in both primary and secondary prevention of cardiovascular diseases (CVDs). Clinicians should strongly consider therapy with ω-3 PUFAs for individuals at risk for CVD and with known CVD, particularly individuals who are at increased risk for sudden cardiac death. The amount of ω-3 PUFA in erythrocyte membranes, which is the ω-3 index, could prove to be a modifiable risk factor for CVD. This review outlines potential mechanisms of action, the ω-3 index, results of clinical and prevention trials, and recommendations for ω-3 PUFA therapy in CVD. The majority of epidemiologic and controlled interventional studies have demonstrated that marine- and plant-derived ω-3 PUFAs have beneficial effects on CVD. The ω-3 index may prove to be a valuable tool for assessing an individual's need for increased ω-3 PUFAs through diet or supplementation.

Authors+Show Affiliations

Alternative Solutions for Health, Bloomington, MN, USA. sjbarrettnd@gmail.com

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23981464

Citation

Barrett, Sara Jean. "The Role of Omega-3 Polyunsaturated Fatty Acids in Cardiovascular Health." Alternative Therapies in Health and Medicine, vol. 19 Suppl 1, 2013, pp. 26-30.
Barrett SJ. The role of omega-3 polyunsaturated fatty acids in cardiovascular health. Altern Ther Health Med. 2013;19 Suppl 1:26-30.
Barrett, S. J. (2013). The role of omega-3 polyunsaturated fatty acids in cardiovascular health. Alternative Therapies in Health and Medicine, 19 Suppl 1, 26-30.
Barrett SJ. The Role of Omega-3 Polyunsaturated Fatty Acids in Cardiovascular Health. Altern Ther Health Med. 2013;19 Suppl 1:26-30. PubMed PMID: 23981464.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The role of omega-3 polyunsaturated fatty acids in cardiovascular health. A1 - Barrett,Sara Jean, PY - 2013/8/29/entrez PY - 2013/9/18/pubmed PY - 2014/4/16/medline SP - 26 EP - 30 JF - Alternative therapies in health and medicine JO - Altern Ther Health Med VL - 19 Suppl 1 N2 - Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) play an important role in both primary and secondary prevention of cardiovascular diseases (CVDs). Clinicians should strongly consider therapy with ω-3 PUFAs for individuals at risk for CVD and with known CVD, particularly individuals who are at increased risk for sudden cardiac death. The amount of ω-3 PUFA in erythrocyte membranes, which is the ω-3 index, could prove to be a modifiable risk factor for CVD. This review outlines potential mechanisms of action, the ω-3 index, results of clinical and prevention trials, and recommendations for ω-3 PUFA therapy in CVD. The majority of epidemiologic and controlled interventional studies have demonstrated that marine- and plant-derived ω-3 PUFAs have beneficial effects on CVD. The ω-3 index may prove to be a valuable tool for assessing an individual's need for increased ω-3 PUFAs through diet or supplementation. SN - 1078-6791 UR - https://www.unboundmedicine.com/medline/citation/23981464/The_role_of_omega_3_polyunsaturated_fatty_acids_in_cardiovascular_health_ L2 - https://medlineplus.gov/dietarysupplements.html DB - PRIME DP - Unbound Medicine ER -