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Betel quid chewing and upper aerodigestive tract cancers: a prospective cohort study in khon kaen, Thailand.
Asian Pac J Cancer Prev. 2013; 14(7):4335-8.AP

Abstract

BACKGROUND

This study aimed to determine the association between betel quid chewing and the occurrence of upper aerodigestive tract (UADT) cancers.

METHODS

A cohort of 17,388 subjects, recruited and interviewed over the 1990-2001 period, in Khon Kaen, Thailand, was followed up until 2011. The data were linked to the Khon Kaen Population-Based Cancer Registry.

RESULTS

The prevalence of betel quid chewing was 15.9%, with a female predominance (97.7%); the mean age of chewers was 57.7 years (SD 6.6). The overall incidence of UADT cancers from the cohort was 14.7 per 100,000 person-years, whereas the incidence among the chewers was 45.7. Betel nut chewing was the only major risk factor for UADT cancers in this population (HR=5.26, 95%CI=2.51- 11.0), while weak associations were found for tobacco smoking and alcohol (HR=1.16, 95%CI=0.45-3.01 and 1.47, 95%CI=0.72-3.03 respectively).

CONCLUSIONS

We found betel quid chewing to be a main risk factor for UADT cancers, resulting in a higher incidence in females. However, further study is required to explore the potential risk factors among non-chewers, non-smokers, and non-drinkers.

Authors+Show Affiliations

Nongkungsri Public Health Office, Kalasin, Thailand.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23991999

Citation

Kampangsri, Wilas, et al. "Betel Quid Chewing and Upper Aerodigestive Tract Cancers: a Prospective Cohort Study in Khon Kaen, Thailand." Asian Pacific Journal of Cancer Prevention : APJCP, vol. 14, no. 7, 2013, pp. 4335-8.
Kampangsri W, Vatanasapt P, Kamsa-Ard S, et al. Betel quid chewing and upper aerodigestive tract cancers: a prospective cohort study in khon kaen, Thailand. Asian Pac J Cancer Prev. 2013;14(7):4335-8.
Kampangsri, W., Vatanasapt, P., Kamsa-Ard, S., Suwanrungruang, K., & Promthet, S. (2013). Betel quid chewing and upper aerodigestive tract cancers: a prospective cohort study in khon kaen, Thailand. Asian Pacific Journal of Cancer Prevention : APJCP, 14(7), 4335-8.
Kampangsri W, et al. Betel Quid Chewing and Upper Aerodigestive Tract Cancers: a Prospective Cohort Study in Khon Kaen, Thailand. Asian Pac J Cancer Prev. 2013;14(7):4335-8. PubMed PMID: 23991999.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Betel quid chewing and upper aerodigestive tract cancers: a prospective cohort study in khon kaen, Thailand. AU - Kampangsri,Wilas, AU - Vatanasapt,Patravoot, AU - Kamsa-Ard,Siriporn, AU - Suwanrungruang,Krittika, AU - Promthet,Supannee, PY - 2013/9/3/entrez PY - 2013/9/3/pubmed PY - 2014/3/19/medline SP - 4335 EP - 8 JF - Asian Pacific journal of cancer prevention : APJCP JO - Asian Pac J Cancer Prev VL - 14 IS - 7 N2 - BACKGROUND: This study aimed to determine the association between betel quid chewing and the occurrence of upper aerodigestive tract (UADT) cancers. METHODS: A cohort of 17,388 subjects, recruited and interviewed over the 1990-2001 period, in Khon Kaen, Thailand, was followed up until 2011. The data were linked to the Khon Kaen Population-Based Cancer Registry. RESULTS: The prevalence of betel quid chewing was 15.9%, with a female predominance (97.7%); the mean age of chewers was 57.7 years (SD 6.6). The overall incidence of UADT cancers from the cohort was 14.7 per 100,000 person-years, whereas the incidence among the chewers was 45.7. Betel nut chewing was the only major risk factor for UADT cancers in this population (HR=5.26, 95%CI=2.51- 11.0), while weak associations were found for tobacco smoking and alcohol (HR=1.16, 95%CI=0.45-3.01 and 1.47, 95%CI=0.72-3.03 respectively). CONCLUSIONS: We found betel quid chewing to be a main risk factor for UADT cancers, resulting in a higher incidence in females. However, further study is required to explore the potential risk factors among non-chewers, non-smokers, and non-drinkers. SN - 2476-762X UR - https://www.unboundmedicine.com/medline/citation/23991999/Betel_quid_chewing_and_upper_aerodigestive_tract_cancers:_a_prospective_cohort_study_in_khon_kaen_Thailand_ L2 - http://journal.waocp.org/?sid=Entrez:PubMed&id=pmid:23991999&key=2013.14.7.4335 DB - PRIME DP - Unbound Medicine ER -