Citation
Kume, Kiyoshi, et al. "Impact of Contrast-induced Acute Kidney Injury On Outcomes in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention." Cardiovascular Revascularization Medicine : Including Molecular Interventions, vol. 14, no. 5, 2013, pp. 253-7.
Kume K, Yasuoka Y, Adachi H, et al. Impact of contrast-induced acute kidney injury on outcomes in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Cardiovasc Revasc Med. 2013;14(5):253-7.
Kume, K., Yasuoka, Y., Adachi, H., Noda, Y., Hattori, S., Araki, R., Kohama, Y., Imanaka, T., Matsutera, R., Kosugi, M., & Sasaki, T. (2013). Impact of contrast-induced acute kidney injury on outcomes in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Cardiovascular Revascularization Medicine : Including Molecular Interventions, 14(5), 253-7. https://doi.org/10.1016/j.carrev.2013.07.009
Kume K, et al. Impact of Contrast-induced Acute Kidney Injury On Outcomes in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. Cardiovasc Revasc Med. 2013 Sep-Oct;14(5):253-7. PubMed PMID: 23993293.
TY - JOUR
T1 - Impact of contrast-induced acute kidney injury on outcomes in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.
AU - Kume,Kiyoshi,
AU - Yasuoka,Yoshinori,
AU - Adachi,Hidenori,
AU - Noda,Yoshiki,
AU - Hattori,Susumu,
AU - Araki,Ryo,
AU - Kohama,Yasuaki,
AU - Imanaka,Takahiro,
AU - Matsutera,Ryo,
AU - Kosugi,Motohiro,
AU - Sasaki,Tatsuya,
Y1 - 2013/08/28/
PY - 2013/05/31/received
PY - 2013/07/22/revised
PY - 2013/07/22/accepted
PY - 2013/9/3/entrez
PY - 2013/9/3/pubmed
PY - 2014/4/23/medline
KW - Contrast-induced acute kidney injury
KW - Primary percutaneous coronary intervention
KW - Renal insufficiency
KW - ST-segment elevation myocardial infarction
SP - 253
EP - 7
JF - Cardiovascular revascularization medicine : including molecular interventions
JO - Cardiovasc Revasc Med
VL - 14
IS - 5
N2 - PURPOSE: The purpose of this study was to identify predictors of contrast-induced acute kidney injury (CI-AKI) and the effect of CI-AKI on cardiovascular outcomes after hospital discharge in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). METHODS AND MATERIALS: We retrospectively reviewed 194 STEMI consecutive patients who underwent primary PCI to evaluate the predictors for CI-AKI and 187 survivors to examine all-cause mortality and cardiovascular events. Outcomes were compared between patients with CI-AKI and those without CI-AKI, which was defined as an increase >50% or >0.5mg/dl in serum creatinine concentration within 48hours after primary PCI. RESULTS: CI-AKI occurred in 23 patients (11.9%). Multivariate analysis identified pre-procedural renal insufficiency as a predictor of CI-AKI, and this predictor was independent from hemodynamic instability and excessive contrast volume. Receiver-operator characteristics analysis demonstrated that patients with an estimated glomerular filtration rate (eGFR) of ≤43.6ml/min per 1.73m(2) had the potential for CI-AKI. Patients who developed CI-AKI had higher mortality and cardiovascular events than did those without CI-AKI (27.8% vs. 4.7%; log-rank P=.0003, 27.8% vs. 11.2%; log-rank P=.0181, respectively). Cox proportional hazards model analysis identified CI-AKI as the independent predictor of mortality and cardiovascular events [hazard ratio [HR]=5.36; P=.0076, HR=3.10; P=.0250, respectively]. CONCLUSIONS: The risk of CI-AKI is increased in patients with pre-procedural renal insufficiency, and eGFR is clinically useful in the emergent setting for CI-AKI risk stratification before primary PCI.
SN - 1878-0938
UR - https://www.unboundmedicine.com/medline/citation/23993293/Impact_of_contrast_induced_acute_kidney_injury_on_outcomes_in_patients_with_ST_segment_elevation_myocardial_infarction_undergoing_primary_percutaneous_coronary_intervention_
L2 - https://linkinghub.elsevier.com/retrieve/pii/S1553-8389(13)00118-8
DB - PRIME
DP - Unbound Medicine
ER -