TY - JOUR T1 - Integrated mass spectrometry approach to profile proanthocyanidins occurring in food supplements: analysis of Potentilla erecta L. rhizomes. AU - Mari,Angela, AU - Eletto,Daniela, AU - Pizza,Cosimo, AU - Montoro,Paola, AU - Piacente,Sonia, Y1 - 2013/07/02/ PY - 2013/03/19/received PY - 2013/06/21/revised PY - 2013/06/24/accepted PY - 2013/9/3/entrez PY - 2013/9/3/pubmed PY - 2014/3/29/medline KW - LC–ESIMS KW - MALDIMS KW - Potentilla erecta KW - Proanthocyanidins SP - 4171 EP - 8 JF - Food chemistry JO - Food Chem VL - 141 IS - 4 N2 - Potentilla erecta (L.) is known for the high concentration of proanthocyanidin oligomers (PAs) in its underground parts. The use of its preparations as food supplements and the lack of chemical-analytical studies concerning with an efficient chromatographic separation procedure for these compounds led us to develop a strategy to profile PAs occurring in this species. Their presence has been rationalised on the basis of mass spectrometric profiles. Direct flow injection/electrospray ionisation (ESI)/ion trap (IT) mass spectrometry was used to investigate the hydroalcoholic extract of P. erecta. To achieve deeper structural information and to focus the analysis on PAs with high polimerisation degree (DP), matrix assisted laser desorption ionisation (MALDI)-time of flight (TOF)-mass spectrometry, was used. Finally, liquid chromatography tandem mass spectrometry (LC-MS(2)) analyses were executed by using a diol stationary phase to detect PAs from DP1 to DP10. Results suggested that all of them were B-type procyanidins with 4→8 linkages. SN - 1873-7072 UR - https://www.unboundmedicine.com/medline/citation/23993602/Integrated_mass_spectrometry_approach_to_profile_proanthocyanidins_occurring_in_food_supplements:_analysis_of_Potentilla_erecta_L__rhizomes_ DB - PRIME DP - Unbound Medicine ER -