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Whole-heart cine MRI in a single breath-hold--a compressed sensing accelerated 3D acquisition technique for assessment of cardiac function.
Rofo 2014; 186(1):37-41ROFO

Abstract

PURPOSE

The aim of this study was to perform functional MR imaging of the whole heart in a single breath-hold using an undersampled 3 D trajectory for data acquisition in combination with compressed sensing for image reconstruction.

MATERIALS AND METHODS

Measurements were performed using an SSFP sequence on a 3 T whole-body system equipped with a 32-channel body array coil. A 3 D radial stack-of-stars sampling scheme was utilized enabling efficient undersampling of the k-space and thereby accelerating data acquisition. Compressed sensing was applied for the reconstruction of the missing data. A validation study was performed based on a fully sampled dataset acquired by standard Cartesian cine imaging of 2 D slices on a healthy volunteer. The results were investigated with regard to systematic errors and resolution losses possibly introduced by the developed reconstruction. Subsequently, the proposed technique was applied for in-vivo functional cardiac imaging of the whole heart in a single breath-hold of 27 s. The developed technique was tested on three healthy volunteers to examine its reproducibility.

RESULTS

By means of the results of the simulation (temporal resolution: 47 ms, spatial resolution: 1.4 × 1.4 × 8 mm, 3 D image matrix: 208 × 208 × 10), an overall acceleration factor of 10 has been found where the compressed sensing reconstructed image series shows only very low systematic errors and a slight in-plane resolution loss of 15 %. The results of the in-vivo study (temporal resolution: 40.5 ms, spatial resolution: 2.1 × 2.1 × 8 mm, 3 D image matrix: 224 × 224 × 12) performed with an acceleration factor of 10.7 confirm the overall good image quality of the presented technique for undersampled acquisitions.

CONCLUSION

The combination of 3 D radial data acquisition and model-based compressed sensing reconstruction allows high acceleration factors enabling cardiac functional imaging of the whole heart within only one breath-hold. The image quality in the simulated dataset and the in-vivo measurement highlights the great potential of the presented technique for an efficient assessment of cardiac functional parameters.

Authors+Show Affiliations

Institute of Radiology, University of Würzburg.Institute of Radiology, University of Würzburg.Institute of Radiology, University of Würzburg.Institute of Radiology, University of Würzburg.Institute of Radiology, University of Würzburg.Institute of Radiology, University of Würzburg.Institute of Radiology, University of Würzburg.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23996623

Citation

Wech, T, et al. "Whole-heart Cine MRI in a Single Breath-hold--a Compressed Sensing Accelerated 3D Acquisition Technique for Assessment of Cardiac Function." RoFo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin, vol. 186, no. 1, 2014, pp. 37-41.
Wech T, Pickl W, Tran-Gia J, et al. Whole-heart cine MRI in a single breath-hold--a compressed sensing accelerated 3D acquisition technique for assessment of cardiac function. Rofo. 2014;186(1):37-41.
Wech, T., Pickl, W., Tran-Gia, J., Ritter, C., Beer, M., Hahn, D., & Köstler, H. (2014). Whole-heart cine MRI in a single breath-hold--a compressed sensing accelerated 3D acquisition technique for assessment of cardiac function. RoFo : Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin, 186(1), pp. 37-41. doi:10.1055/s-0033-1350521.
Wech T, et al. Whole-heart Cine MRI in a Single Breath-hold--a Compressed Sensing Accelerated 3D Acquisition Technique for Assessment of Cardiac Function. Rofo. 2014;186(1):37-41. PubMed PMID: 23996623.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Whole-heart cine MRI in a single breath-hold--a compressed sensing accelerated 3D acquisition technique for assessment of cardiac function. AU - Wech,T, AU - Pickl,W, AU - Tran-Gia,J, AU - Ritter,C, AU - Beer,M, AU - Hahn,D, AU - Köstler,H, Y1 - 2013/08/30/ PY - 2013/9/3/entrez PY - 2013/9/3/pubmed PY - 2014/6/3/medline SP - 37 EP - 41 JF - RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin JO - Rofo VL - 186 IS - 1 N2 - PURPOSE: The aim of this study was to perform functional MR imaging of the whole heart in a single breath-hold using an undersampled 3 D trajectory for data acquisition in combination with compressed sensing for image reconstruction. MATERIALS AND METHODS: Measurements were performed using an SSFP sequence on a 3 T whole-body system equipped with a 32-channel body array coil. A 3 D radial stack-of-stars sampling scheme was utilized enabling efficient undersampling of the k-space and thereby accelerating data acquisition. Compressed sensing was applied for the reconstruction of the missing data. A validation study was performed based on a fully sampled dataset acquired by standard Cartesian cine imaging of 2 D slices on a healthy volunteer. The results were investigated with regard to systematic errors and resolution losses possibly introduced by the developed reconstruction. Subsequently, the proposed technique was applied for in-vivo functional cardiac imaging of the whole heart in a single breath-hold of 27 s. The developed technique was tested on three healthy volunteers to examine its reproducibility. RESULTS: By means of the results of the simulation (temporal resolution: 47 ms, spatial resolution: 1.4 × 1.4 × 8 mm, 3 D image matrix: 208 × 208 × 10), an overall acceleration factor of 10 has been found where the compressed sensing reconstructed image series shows only very low systematic errors and a slight in-plane resolution loss of 15 %. The results of the in-vivo study (temporal resolution: 40.5 ms, spatial resolution: 2.1 × 2.1 × 8 mm, 3 D image matrix: 224 × 224 × 12) performed with an acceleration factor of 10.7 confirm the overall good image quality of the presented technique for undersampled acquisitions. CONCLUSION: The combination of 3 D radial data acquisition and model-based compressed sensing reconstruction allows high acceleration factors enabling cardiac functional imaging of the whole heart within only one breath-hold. The image quality in the simulated dataset and the in-vivo measurement highlights the great potential of the presented technique for an efficient assessment of cardiac functional parameters. SN - 1438-9010 UR - https://www.unboundmedicine.com/medline/citation/23996623/Whole_heart_cine_MRI_in_a_single_breath_hold__a_compressed_sensing_accelerated_3D_acquisition_technique_for_assessment_of_cardiac_function_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-0033-1350521 DB - PRIME DP - Unbound Medicine ER -