Tags

Type your tag names separated by a space and hit enter

In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei.
Antimicrob Agents Chemother. 2013 Nov; 57(11):5771-3.AA

Abstract

This study aimed at investigating the in vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against Burkholderia pseudomallei in planktonic and biofilm forms, through broth microdilution and resazurin-based viability staining, respectively. In planktonic growth, the strains were susceptible to the drugs, while in biofilm growth, significantly higher antimicrobial concentrations were required, especially for ceftazidime and imipenem, surpassing the resistance breakpoints. These results highlight the importance of the routine evaluation of biofilm antimicrobial susceptibility.

Authors+Show Affiliations

Specialized Medical Mycology Center, Federal University of Ceará, Fortaleza, Ceará, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24002089

Citation

Bandeira, Tereza de Jesus Pinheiro Gomes, et al. "In Vitro Activities of Amoxicillin-clavulanate, Doxycycline, Ceftazidime, Imipenem, and Trimethoprim-sulfamethoxazole Against Biofilm of Brazilian Strains of Burkholderia Pseudomallei." Antimicrobial Agents and Chemotherapy, vol. 57, no. 11, 2013, pp. 5771-3.
Bandeira Tde J, Moreira CA, Brilhante RS, et al. In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei. Antimicrob Agents Chemother. 2013;57(11):5771-3.
Bandeira, T. d. e. . J., Moreira, C. A., Brilhante, R. S., Castelo-Branco, D. d. e. . S., Neto, M. P., Cordeiro, R. d. e. . A., Rodrigues, T. d. e. . J., Rocha, M. F., & Sidrim, J. J. (2013). In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei. Antimicrobial Agents and Chemotherapy, 57(11), 5771-3. https://doi.org/10.1128/AAC.00721-13
Bandeira Tde J, et al. In Vitro Activities of Amoxicillin-clavulanate, Doxycycline, Ceftazidime, Imipenem, and Trimethoprim-sulfamethoxazole Against Biofilm of Brazilian Strains of Burkholderia Pseudomallei. Antimicrob Agents Chemother. 2013;57(11):5771-3. PubMed PMID: 24002089.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against biofilm of Brazilian strains of Burkholderia pseudomallei. AU - Bandeira,Tereza de Jesus Pinheiro Gomes, AU - Moreira,Camila Alencar, AU - Brilhante,Raimunda Sâmia Nogueira, AU - Castelo-Branco,Débora de Souza Collares Maia, AU - Neto,Manoel Paiva de Araújo, AU - Cordeiro,Rossana de Aguiar, AU - Rodrigues,Terezinha de Jesus Santos, AU - Rocha,Marcos Fábio Gadelha, AU - Sidrim,José Júlio Costa, Y1 - 2013/09/03/ PY - 2013/9/5/entrez PY - 2013/9/5/pubmed PY - 2014/5/16/medline SP - 5771 EP - 3 JF - Antimicrobial agents and chemotherapy JO - Antimicrob Agents Chemother VL - 57 IS - 11 N2 - This study aimed at investigating the in vitro activities of amoxicillin-clavulanate, doxycycline, ceftazidime, imipenem, and trimethoprim-sulfamethoxazole against Burkholderia pseudomallei in planktonic and biofilm forms, through broth microdilution and resazurin-based viability staining, respectively. In planktonic growth, the strains were susceptible to the drugs, while in biofilm growth, significantly higher antimicrobial concentrations were required, especially for ceftazidime and imipenem, surpassing the resistance breakpoints. These results highlight the importance of the routine evaluation of biofilm antimicrobial susceptibility. SN - 1098-6596 UR - https://www.unboundmedicine.com/medline/citation/24002089/In_vitro_activities_of_amoxicillin_clavulanate_doxycycline_ceftazidime_imipenem_and_trimethoprim_sulfamethoxazole_against_biofilm_of_Brazilian_strains_of_Burkholderia_pseudomallei_ L2 - http://aac.asm.org/cgi/pmidlookup?view=long&pmid=24002089 DB - PRIME DP - Unbound Medicine ER -