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[Central motor conduction time (CMCT) in hereditary motor sensory neuropathy type I (HMSN type I)].
Rinsho Shinkeigaku. 1990 May; 30(5):487-91.RS

Abstract

The motor system of 13 cases with hereditary motor sensory neuropathy (HMSN) type I were analysed by clinical neurophysiological method. The motor conduction velocity (MCV) and F wave latency in lower motor neurone were markedly delayed. The latency of the muscle evoked potential (MEP) by cortical magnetic stimulation were also markedly delayed. The central motor conduction times (CMCT) were calculated by two methods. CMCT-mag was calculated by subtraction of the MEP by cervical magnetic stimulation from the MEP by cortical magnetic stimulation. CMCT-f was calculated by subtraction of the [(F wave latency -1 + distal latency)/2] from the MEP by cortical magnetic stimulation. There were positive correlation between CMCT-f and CMCT-mag. CMCT of HMSN type I were divided to two groups. CMCT of the first group was markedly delayed. CMCT of the second group was mildly delayed or normal. The former group showed marked weakness in distal muscles clinically. The latter group showed mild or moderate weakness in distal muscles clinically. All these patients did not show any pyramidal tract signs, which could be covered by severe lower motor neurone involvements. The classification of HMSN type I by gene was well known, genetical analysis might be important to these groups in HMSN type I.

Authors+Show Affiliations

Department of Neurology, Nara Medical University.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

jpn

PubMed ID

2401109

Citation

Mano, Y, et al. "[Central Motor Conduction Time (CMCT) in Hereditary Motor Sensory Neuropathy Type I (HMSN Type I)]." Rinsho Shinkeigaku = Clinical Neurology, vol. 30, no. 5, 1990, pp. 487-91.
Mano Y, Nakamuro T, Ikoma K, et al. [Central motor conduction time (CMCT) in hereditary motor sensory neuropathy type I (HMSN type I)]. Rinsho Shinkeigaku. 1990;30(5):487-91.
Mano, Y., Nakamuro, T., Ikoma, K., & Takayanagi, T. (1990). [Central motor conduction time (CMCT) in hereditary motor sensory neuropathy type I (HMSN type I)]. Rinsho Shinkeigaku = Clinical Neurology, 30(5), 487-91.
Mano Y, et al. [Central Motor Conduction Time (CMCT) in Hereditary Motor Sensory Neuropathy Type I (HMSN Type I)]. Rinsho Shinkeigaku. 1990;30(5):487-91. PubMed PMID: 2401109.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Central motor conduction time (CMCT) in hereditary motor sensory neuropathy type I (HMSN type I)]. AU - Mano,Y, AU - Nakamuro,T, AU - Ikoma,K, AU - Takayanagi,T, PY - 1990/5/1/pubmed PY - 1990/5/1/medline PY - 1990/5/1/entrez SP - 487 EP - 91 JF - Rinsho shinkeigaku = Clinical neurology JO - Rinsho Shinkeigaku VL - 30 IS - 5 N2 - The motor system of 13 cases with hereditary motor sensory neuropathy (HMSN) type I were analysed by clinical neurophysiological method. The motor conduction velocity (MCV) and F wave latency in lower motor neurone were markedly delayed. The latency of the muscle evoked potential (MEP) by cortical magnetic stimulation were also markedly delayed. The central motor conduction times (CMCT) were calculated by two methods. CMCT-mag was calculated by subtraction of the MEP by cervical magnetic stimulation from the MEP by cortical magnetic stimulation. CMCT-f was calculated by subtraction of the [(F wave latency -1 + distal latency)/2] from the MEP by cortical magnetic stimulation. There were positive correlation between CMCT-f and CMCT-mag. CMCT of HMSN type I were divided to two groups. CMCT of the first group was markedly delayed. CMCT of the second group was mildly delayed or normal. The former group showed marked weakness in distal muscles clinically. The latter group showed mild or moderate weakness in distal muscles clinically. All these patients did not show any pyramidal tract signs, which could be covered by severe lower motor neurone involvements. The classification of HMSN type I by gene was well known, genetical analysis might be important to these groups in HMSN type I. SN - 0009-918X UR - https://www.unboundmedicine.com/medline/citation/2401109/[Central_motor_conduction_time__CMCT__in_hereditary_motor_sensory_neuropathy_type_I__HMSN_type_I_]_ L2 - http://www.diseaseinfosearch.org/result/4890 DB - PRIME DP - Unbound Medicine ER -