Tags

Type your tag names separated by a space and hit enter

Mutagenicity and genotoxicity in gill erythrocyte cells of Poecilia reticulata exposed to a glyphosate formulation.
Bull Environ Contam Toxicol. 2013 Nov; 91(5):583-7.BE

Abstract

Poecilia reticulata were exposed to herbicide Roundup Transorb(®) for micronucleus test, nuclear abnormalities and comet assay. The exposure-concentrations were based on CL50-96 h following 0, 1.41, 2.83, 4.24 and 5.65 μL L(-1) for 24 h. Micronucleus and comets were significantly increased in the gill erythrocyte cells after herbicide exposure compared with the non-exposed group. Results showed a gradual increase in the number of damaged cells, indicating a concentration-dependent effect and that this herbicide was mutagenic and genotoxic to P. reticulata and this effect could be attributed to a combination of compounds contained in the formulation with the active ingredient glyphosate.

Authors+Show Affiliations

Departamento de Genética e Morfologia, Instituto de Ciências Biológicas, Universidade de Brasília, Brasília, DF, CEP 70919-970, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24042842

Citation

De Souza Filho, José, et al. "Mutagenicity and Genotoxicity in Gill Erythrocyte Cells of Poecilia Reticulata Exposed to a Glyphosate Formulation." Bulletin of Environmental Contamination and Toxicology, vol. 91, no. 5, 2013, pp. 583-7.
De Souza Filho J, Sousa CC, Da Silva CC, et al. Mutagenicity and genotoxicity in gill erythrocyte cells of Poecilia reticulata exposed to a glyphosate formulation. Bull Environ Contam Toxicol. 2013;91(5):583-7.
De Souza Filho, J., Sousa, C. C., Da Silva, C. C., De Sabóia-Morais, S. M., & Grisolia, C. K. (2013). Mutagenicity and genotoxicity in gill erythrocyte cells of Poecilia reticulata exposed to a glyphosate formulation. Bulletin of Environmental Contamination and Toxicology, 91(5), 583-7. https://doi.org/10.1007/s00128-013-1103-7
De Souza Filho J, et al. Mutagenicity and Genotoxicity in Gill Erythrocyte Cells of Poecilia Reticulata Exposed to a Glyphosate Formulation. Bull Environ Contam Toxicol. 2013;91(5):583-7. PubMed PMID: 24042842.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mutagenicity and genotoxicity in gill erythrocyte cells of Poecilia reticulata exposed to a glyphosate formulation. AU - De Souza Filho,José, AU - Sousa,Caio César Neves, AU - Da Silva,Cláudio Carlos, AU - De Sabóia-Morais,Simone Maria Teixeira, AU - Grisolia,Cesar Koppe, Y1 - 2013/09/17/ PY - 2013/03/04/received PY - 2013/09/06/accepted PY - 2013/9/18/entrez PY - 2013/9/18/pubmed PY - 2014/4/2/medline SP - 583 EP - 7 JF - Bulletin of environmental contamination and toxicology JO - Bull Environ Contam Toxicol VL - 91 IS - 5 N2 - Poecilia reticulata were exposed to herbicide Roundup Transorb(®) for micronucleus test, nuclear abnormalities and comet assay. The exposure-concentrations were based on CL50-96 h following 0, 1.41, 2.83, 4.24 and 5.65 μL L(-1) for 24 h. Micronucleus and comets were significantly increased in the gill erythrocyte cells after herbicide exposure compared with the non-exposed group. Results showed a gradual increase in the number of damaged cells, indicating a concentration-dependent effect and that this herbicide was mutagenic and genotoxic to P. reticulata and this effect could be attributed to a combination of compounds contained in the formulation with the active ingredient glyphosate. SN - 1432-0800 UR - https://www.unboundmedicine.com/medline/citation/24042842/Mutagenicity_and_genotoxicity_in_gill_erythrocyte_cells_of_Poecilia_reticulata_exposed_to_a_glyphosate_formulation_ L2 - https://dx.doi.org/10.1007/s00128-013-1103-7 DB - PRIME DP - Unbound Medicine ER -