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Examination of the phenolic profile and antioxidant activity of the leaves of the Australian native plant Smilax glyciphylla.
J Nat Prod. 2013 Oct 25; 76(10):1930-6.JN

Abstract

Together with the sweet principle component glycyphyllin A (3), seven phenolic compounds including two new dihydrochalcone rhamnopyranosides, glycyphyllin B (1) and glycyphyllin C (2), and five known flavonoids, catechin (4), kaempferol-3-O-β-D-glucopyranoside (5), quercetin-3-O-β-D-glucopyranoside (6), kaempferol-3-O-β-neohesperidoside (7), and 2R,3R-dihydrokaempferol-3-O-β-D-glucopyranoside (8), have been isolated from the ethanolic extract of the leaves of Smilax glyciphylla for the first time. The structures of these compounds were characterized by spectroscopic methods including UV, MS, and 1D and 2D NMR. In vitro antioxidant capacity tests employing FRAP and DPPH assays indicated that 1, 4, and 6 exhibited potent antioxidant activity and are the key phenolics responsible for the antioxidant activity of the leaf extract of S. glyciphylla.

Authors+Show Affiliations

School of Agriculture, Food and Wine, The University of Adelaide , Waite Campus, Urrbrae 5064, Adelaide, South Australia, Australia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24050300

Citation

Huang, An-Cheng, et al. "Examination of the Phenolic Profile and Antioxidant Activity of the Leaves of the Australian Native Plant Smilax Glyciphylla." Journal of Natural Products, vol. 76, no. 10, 2013, pp. 1930-6.
Huang AC, Wilde A, Ebmeyer J, et al. Examination of the phenolic profile and antioxidant activity of the leaves of the Australian native plant Smilax glyciphylla. J Nat Prod. 2013;76(10):1930-6.
Huang, A. C., Wilde, A., Ebmeyer, J., Skouroumounis, G. K., & Taylor, D. K. (2013). Examination of the phenolic profile and antioxidant activity of the leaves of the Australian native plant Smilax glyciphylla. Journal of Natural Products, 76(10), 1930-6. https://doi.org/10.1021/np4005163
Huang AC, et al. Examination of the Phenolic Profile and Antioxidant Activity of the Leaves of the Australian Native Plant Smilax Glyciphylla. J Nat Prod. 2013 Oct 25;76(10):1930-6. PubMed PMID: 24050300.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Examination of the phenolic profile and antioxidant activity of the leaves of the Australian native plant Smilax glyciphylla. AU - Huang,An-Cheng, AU - Wilde,Amelie, AU - Ebmeyer,Johanna, AU - Skouroumounis,George K, AU - Taylor,Dennis K, Y1 - 2013/09/20/ PY - 2013/9/21/entrez PY - 2013/9/21/pubmed PY - 2014/1/7/medline SP - 1930 EP - 6 JF - Journal of natural products JO - J Nat Prod VL - 76 IS - 10 N2 - Together with the sweet principle component glycyphyllin A (3), seven phenolic compounds including two new dihydrochalcone rhamnopyranosides, glycyphyllin B (1) and glycyphyllin C (2), and five known flavonoids, catechin (4), kaempferol-3-O-β-D-glucopyranoside (5), quercetin-3-O-β-D-glucopyranoside (6), kaempferol-3-O-β-neohesperidoside (7), and 2R,3R-dihydrokaempferol-3-O-β-D-glucopyranoside (8), have been isolated from the ethanolic extract of the leaves of Smilax glyciphylla for the first time. The structures of these compounds were characterized by spectroscopic methods including UV, MS, and 1D and 2D NMR. In vitro antioxidant capacity tests employing FRAP and DPPH assays indicated that 1, 4, and 6 exhibited potent antioxidant activity and are the key phenolics responsible for the antioxidant activity of the leaf extract of S. glyciphylla. SN - 1520-6025 UR - https://www.unboundmedicine.com/medline/citation/24050300/Examination_of_the_phenolic_profile_and_antioxidant_activity_of_the_leaves_of_the_Australian_native_plant_Smilax_glyciphylla_ L2 - https://doi.org/10.1021/np4005163 DB - PRIME DP - Unbound Medicine ER -