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[A woman with paraneoplastic dermatoses; signs of recurrent malignancy].
Ned Tijdschr Geneeskd. 2013; 157(38):A6560.NT

Abstract

BACKGROUND

Paraneoplastic dermatoses may be the first manifestation of a malignancy. Rapid recognition is therefore important.

CASE DESCRIPTION

A 72-year-old woman who had been treated in the past for metastasised neuroendocrine carcinoma and had undergone curative treatment for stage-1c endometrial carcinoma developed three paraneoplastic dermatoses over a 2-year period: acanthosis nigricans, tripe palms and acquired hypertrichosis lanuginosa. Half a year later, cutaneous metastases derived from the endometrial carcinoma treated 12 years prior were discovered.

CONCLUSION

The development of three paraneoplastic dermatoses in a short period of time is rare. Acanthosis nigricans, tripe palms and acquired hypertrichosis lanuginosa can develop in association with both neuroendocrine and endometrial carcinoma. The sudden development of paraneoplastic dermatoses is frequently a forewarning of progression of the malignancy.

Authors+Show Affiliations

Quint KD
Leids Universitair Medisch Centrum, Leiden.
Edelbroek JR
No affiliation info available
Gelderblom AJ
No affiliation info available
van Doorn R
No affiliation info available
Vermeer MH
No affiliation info available

MeSH

Acanthosis NigricansAgedCarcinoma, NeuroendocrineEndometrial NeoplasmsFatal OutcomeFemaleHand DermatosesHumansKeratosisParaneoplastic SyndromesSkin DiseasesSkin Neoplasms

Pub Type(s)

Case Reports
Journal Article

Language

dut

PubMed ID

24050449

Citation

Quint, Koen D., et al. "[A Woman With Paraneoplastic Dermatoses; Signs of Recurrent Malignancy]." Nederlands Tijdschrift Voor Geneeskunde, vol. 157, no. 38, 2013, pp. A6560.
Quint KD, Edelbroek JR, Gelderblom AJ, et al. [A woman with paraneoplastic dermatoses; signs of recurrent malignancy]. Ned Tijdschr Geneeskd. 2013;157(38):A6560.
Quint, K. D., Edelbroek, J. R., Gelderblom, A. J., van Doorn, R., & Vermeer, M. H. (2013). [A woman with paraneoplastic dermatoses; signs of recurrent malignancy]. Nederlands Tijdschrift Voor Geneeskunde, 157(38), A6560.
Quint KD, et al. [A Woman With Paraneoplastic Dermatoses; Signs of Recurrent Malignancy]. Ned Tijdschr Geneeskd. 2013;157(38):A6560. PubMed PMID: 24050449.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [A woman with paraneoplastic dermatoses; signs of recurrent malignancy]. AU - Quint,Koen D, AU - Edelbroek,Jeroen R J, AU - Gelderblom,A J Hans, AU - van Doorn,Romco, AU - Vermeer,Maarten H, PY - 2013/9/21/entrez PY - 2013/9/21/pubmed PY - 2014/5/16/medline SP - A6560 EP - A6560 JF - Nederlands tijdschrift voor geneeskunde JO - Ned Tijdschr Geneeskd VL - 157 IS - 38 N2 - BACKGROUND: Paraneoplastic dermatoses may be the first manifestation of a malignancy. Rapid recognition is therefore important. CASE DESCRIPTION: A 72-year-old woman who had been treated in the past for metastasised neuroendocrine carcinoma and had undergone curative treatment for stage-1c endometrial carcinoma developed three paraneoplastic dermatoses over a 2-year period: acanthosis nigricans, tripe palms and acquired hypertrichosis lanuginosa. Half a year later, cutaneous metastases derived from the endometrial carcinoma treated 12 years prior were discovered. CONCLUSION: The development of three paraneoplastic dermatoses in a short period of time is rare. Acanthosis nigricans, tripe palms and acquired hypertrichosis lanuginosa can develop in association with both neuroendocrine and endometrial carcinoma. The sudden development of paraneoplastic dermatoses is frequently a forewarning of progression of the malignancy. SN - 1876-8784 UR - https://www.unboundmedicine.com/medline/citation/24050449/[A_woman_with_paraneoplastic_dermatoses DB - PRIME DP - Unbound Medicine ER -