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Marine-Lenhart syndrome in a young girl.
J Pediatr Endocrinol Metab. 2014 Jan; 27(1-2):189-91.JP

Abstract

Graves' disease is the most common reason of hyperthyroidism in children. Graves' disease with accompanying functioning nodules is defined as Marine-Lenhart syndrome. This syndrome has not been described in children before. Here, a 15-year-old girl with Graves' disease and a coexisting cold nodule is presented. A thyroid scan showed diffuse uptake of Tc-99m pertechnatate in both lobes and decreased uptake in accordance with the left lobe nodule. The nodule was histologically diagnosed as benign. The patient was diagnosed with type 1 diabetes mellitus and polyglandular autoimmune syndrome during clinical follow-up. The differential diagnoses of Graves' disease with coexisting nodules should include the Marine-Lenhart syndrome. Treatment options should be determined taking this rare condition into account.

Authors

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Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

24057592

Citation

Şen, Yaşar, et al. "Marine-Lenhart Syndrome in a Young Girl." Journal of Pediatric Endocrinology & Metabolism : JPEM, vol. 27, no. 1-2, 2014, pp. 189-91.
Şen Y, Cimbek EA, Yuca SA, et al. Marine-Lenhart syndrome in a young girl. J Pediatr Endocrinol Metab. 2014;27(1-2):189-91.
Şen, Y., Cimbek, E. A., Yuca, S. A., Gedik, G. K., & Sarı, O. (2014). Marine-Lenhart syndrome in a young girl. Journal of Pediatric Endocrinology & Metabolism : JPEM, 27(1-2), 189-91. https://doi.org/10.1515/jpem-2013-0302
Şen Y, et al. Marine-Lenhart Syndrome in a Young Girl. J Pediatr Endocrinol Metab. 2014;27(1-2):189-91. PubMed PMID: 24057592.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Marine-Lenhart syndrome in a young girl. AU - Şen,Yaşar, AU - Cimbek,Emine Ayça, AU - Yuca,Sevil Arı, AU - Gedik,Gonca Kara, AU - Sarı,Oktay, PY - 2013/07/20/received PY - 2013/08/14/accepted PY - 2013/9/24/entrez PY - 2013/9/24/pubmed PY - 2016/7/29/medline SP - 189 EP - 91 JF - Journal of pediatric endocrinology & metabolism : JPEM JO - J. Pediatr. Endocrinol. Metab. VL - 27 IS - 1-2 N2 - Graves' disease is the most common reason of hyperthyroidism in children. Graves' disease with accompanying functioning nodules is defined as Marine-Lenhart syndrome. This syndrome has not been described in children before. Here, a 15-year-old girl with Graves' disease and a coexisting cold nodule is presented. A thyroid scan showed diffuse uptake of Tc-99m pertechnatate in both lobes and decreased uptake in accordance with the left lobe nodule. The nodule was histologically diagnosed as benign. The patient was diagnosed with type 1 diabetes mellitus and polyglandular autoimmune syndrome during clinical follow-up. The differential diagnoses of Graves' disease with coexisting nodules should include the Marine-Lenhart syndrome. Treatment options should be determined taking this rare condition into account. SN - 2191-0251 UR - https://www.unboundmedicine.com/medline/citation/24057592/Marine_Lenhart_syndrome_in_a_young_girl_ L2 - https://www.degruyter.com/doi/10.1515/jpem-2013-0302 DB - PRIME DP - Unbound Medicine ER -