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A comparison of percutaneous needle fasciotomy and collagenase injection for dupuytren disease.
J Hand Surg Am. 2013 Dec; 38(12):2377-80.JH

Abstract

PURPOSE

To compare percutaneous needle fasciotomy (PNF) with collagenase injection in the treatment of Dupuytren contracture.

METHODS

A retrospective review was performed for patients with Dupuytren disease treated with PNF or collagenase. Range of motion, patient satisfaction, and complications were recorded.

RESULTS

There were 29 patients in the collagenase group with mean baseline contractures of 40° for 22 affected metacarpophalangeal joints and 50° for 12 affected proximal interphalangeal joints. The PNF group was composed of 30 patients with mean baseline contractures of 37° for 32 affected metacarpophalangeal joints and 41° for 18 affected proximal interphalangeal joints. All patients were observed for a minimum of 3 months. Clinical success (reduction of contracture within 0° to 5° of normal) was accomplished in 35 of 50 joints (67%) in the PNF group and in 19 of 34 joints (56%) in the collagenase group. Patient satisfaction was similar between groups. Only minor complications were observed, including skin tears, ecchymosis, edema, pruritus, and lymphadenopathy.

CONCLUSIONS

In the short term, both PNF and collagenase have similar clinical outcomes and patient satisfaction.

TYPE OF STUDY/LEVEL OF EVIDENCE

Therapeutic III.

Authors+Show Affiliations

Florida Orthopaedic Institute and the Foundation for Orthopaedic Research and Education (FORE), Tampa, FL. Electronic address: orthojason@me.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

24060510

Citation

Nydick, Jason A., et al. "A Comparison of Percutaneous Needle Fasciotomy and Collagenase Injection for Dupuytren Disease." The Journal of Hand Surgery, vol. 38, no. 12, 2013, pp. 2377-80.
Nydick JA, Olliff BW, Garcia MJ, et al. A comparison of percutaneous needle fasciotomy and collagenase injection for dupuytren disease. J Hand Surg Am. 2013;38(12):2377-80.
Nydick, J. A., Olliff, B. W., Garcia, M. J., Hess, A. V., & Stone, J. D. (2013). A comparison of percutaneous needle fasciotomy and collagenase injection for dupuytren disease. The Journal of Hand Surgery, 38(12), 2377-80. https://doi.org/10.1016/j.jhsa.2013.08.096
Nydick JA, et al. A Comparison of Percutaneous Needle Fasciotomy and Collagenase Injection for Dupuytren Disease. J Hand Surg Am. 2013;38(12):2377-80. PubMed PMID: 24060510.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A comparison of percutaneous needle fasciotomy and collagenase injection for dupuytren disease. AU - Nydick,Jason A, AU - Olliff,Bailee W, AU - Garcia,Michael J, AU - Hess,Alfred V, AU - Stone,Jeffrey D, Y1 - 2013/09/20/ PY - 2013/07/18/received PY - 2013/08/07/revised PY - 2013/08/08/accepted PY - 2013/9/25/entrez PY - 2013/9/26/pubmed PY - 2014/8/22/medline KW - Dupuytren KW - collagenase KW - percutaneous needle fasciotomy SP - 2377 EP - 80 JF - The Journal of hand surgery JO - J Hand Surg Am VL - 38 IS - 12 N2 - PURPOSE: To compare percutaneous needle fasciotomy (PNF) with collagenase injection in the treatment of Dupuytren contracture. METHODS: A retrospective review was performed for patients with Dupuytren disease treated with PNF or collagenase. Range of motion, patient satisfaction, and complications were recorded. RESULTS: There were 29 patients in the collagenase group with mean baseline contractures of 40° for 22 affected metacarpophalangeal joints and 50° for 12 affected proximal interphalangeal joints. The PNF group was composed of 30 patients with mean baseline contractures of 37° for 32 affected metacarpophalangeal joints and 41° for 18 affected proximal interphalangeal joints. All patients were observed for a minimum of 3 months. Clinical success (reduction of contracture within 0° to 5° of normal) was accomplished in 35 of 50 joints (67%) in the PNF group and in 19 of 34 joints (56%) in the collagenase group. Patient satisfaction was similar between groups. Only minor complications were observed, including skin tears, ecchymosis, edema, pruritus, and lymphadenopathy. CONCLUSIONS: In the short term, both PNF and collagenase have similar clinical outcomes and patient satisfaction. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic III. SN - 1531-6564 UR - https://www.unboundmedicine.com/medline/citation/24060510/A_comparison_of_percutaneous_needle_fasciotomy_and_collagenase_injection_for_dupuytren_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0363-5023(13)01134-9 DB - PRIME DP - Unbound Medicine ER -