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Colonization by S. aureus increases the EASI and the number of appointments by patients with atopic dermatitis: cohort with 93 patients.
An Bras Dermatol. 2013 Jul-Aug; 88(4):518-21.AB

Abstract

BACKGROUND

Atopic dermatitis leads to epidermal barrier dysfunction and bacteria colonization. The relationship of the last factor with the severity of the disease and the frequency of exacerbation is not fully known.

OBJECTIVES

Verify the severity of the atopic dermatitis and the number of appointments generated by dermatosis, comparing patients colonized with patients not colonized by S. aureus. Verify the frequency of colonization by methicillin resistant Staphylococcus aureus acquired in the community.

METHODS

Cohort study with a 12 months follow-up, in a sample of patients from Porto Alegre, RS public network. Cultures in active injuries and nasal cavities were carried out as well as methicillin sensitivity tests to S. aureus. The severity of atopic dermatitis was defined by Eczema Area and Severity Index (EASI).

RESULTS

We included 93 patients, 43% female and 56% male, 26 colonized by S. aureus in the nasal orifices, 56 in the skin damage. The mean of initial Eczema Area and Severity Index was 5.5 and final 3.9. The initial Eczema Area and Severity Index of patients colonized by S. aureus in the skin and nasal cavity was larger than the number of patients without colonization(p< 0.05). During the period of one year, in average, there were six appointments/patient. There was linear correlation between the number of appointments during one year and the inicial Eczema Area and Severity Index (r = 0,78). There were no patients with methicillin resistant Staphylococcus aureus acquired in the community.

CONCLUSION

There is a relevant influence of staphylococcal colonization on the severity of atopic dermatitis and the number of appointments required by its exacerbation. Methicillin resistance among those affected by S. aureus does not seem to be an emergent problem, in this Brazilian sample.

Links

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Authors+Show Affiliations

Lipnharski C
Universidade de Ciências da Saúde de Porto Alegre, Porto AlegreRSBrazil.
d'Azevedo PA
No affiliation info available
Quinto VP
No affiliation info available
Bessa G
No affiliation info available
Bonamigo RR
No affiliation info available

MeSH

AdolescentAdultAppointments and SchedulesChildChild, PreschoolCohort StudiesDermatitis, AtopicFemaleHumansInfantInfant, NewbornMaleMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsSeverity of Illness IndexSkinStaphylococcus aureusTime FactorsYoung Adult

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24068121

Citation

Lipnharski, Caroline, et al. "Colonization By S. Aureus Increases the EASI and the Number of Appointments By Patients With Atopic Dermatitis: Cohort With 93 Patients." Anais Brasileiros De Dermatologia, vol. 88, no. 4, 2013, pp. 518-21.
Lipnharski C, d'Azevedo PA, Quinto VP, et al. Colonization by S. aureus increases the EASI and the number of appointments by patients with atopic dermatitis: cohort with 93 patients. An Bras Dermatol. 2013;88(4):518-21.
Lipnharski, C., d'Azevedo, P. A., Quinto, V. P., Bessa, G., & Bonamigo, R. R. (2013). Colonization by S. aureus increases the EASI and the number of appointments by patients with atopic dermatitis: cohort with 93 patients. Anais Brasileiros De Dermatologia, 88(4), 518-21. https://doi.org/10.1590/abd1806-4841.20132046
Lipnharski C, et al. Colonization By S. Aureus Increases the EASI and the Number of Appointments By Patients With Atopic Dermatitis: Cohort With 93 Patients. An Bras Dermatol. 2013 Jul-Aug;88(4):518-21. PubMed PMID: 24068121.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Colonization by S. aureus increases the EASI and the number of appointments by patients with atopic dermatitis: cohort with 93 patients. AU - Lipnharski,Caroline, AU - d'Azevedo,Pedro Alves, AU - Quinto,Vanessa Petry, AU - Bessa,Giancarlo, AU - Bonamigo,Renan Rangel, PY - 2012/08/05/received PY - 2012/09/06/accepted PY - 2013/9/27/entrez PY - 2013/9/27/pubmed PY - 2014/4/3/medline SP - 518 EP - 21 JF - Anais brasileiros de dermatologia JO - An Bras Dermatol VL - 88 IS - 4 N2 - BACKGROUND: Atopic dermatitis leads to epidermal barrier dysfunction and bacteria colonization. The relationship of the last factor with the severity of the disease and the frequency of exacerbation is not fully known. OBJECTIVES: Verify the severity of the atopic dermatitis and the number of appointments generated by dermatosis, comparing patients colonized with patients not colonized by S. aureus. Verify the frequency of colonization by methicillin resistant Staphylococcus aureus acquired in the community. METHODS: Cohort study with a 12 months follow-up, in a sample of patients from Porto Alegre, RS public network. Cultures in active injuries and nasal cavities were carried out as well as methicillin sensitivity tests to S. aureus. The severity of atopic dermatitis was defined by Eczema Area and Severity Index (EASI). RESULTS: We included 93 patients, 43% female and 56% male, 26 colonized by S. aureus in the nasal orifices, 56 in the skin damage. The mean of initial Eczema Area and Severity Index was 5.5 and final 3.9. The initial Eczema Area and Severity Index of patients colonized by S. aureus in the skin and nasal cavity was larger than the number of patients without colonization(p< 0.05). During the period of one year, in average, there were six appointments/patient. There was linear correlation between the number of appointments during one year and the inicial Eczema Area and Severity Index (r = 0,78). There were no patients with methicillin resistant Staphylococcus aureus acquired in the community. CONCLUSION: There is a relevant influence of staphylococcal colonization on the severity of atopic dermatitis and the number of appointments required by its exacerbation. Methicillin resistance among those affected by S. aureus does not seem to be an emergent problem, in this Brazilian sample. SN - 1806-4841 UR - https://www.unboundmedicine.com/medline/citation/24068121/Colonization_by_S__aureus_increases_the_EASI_and_the_number_of_appointments_by_patients_with_atopic_dermatitis:_cohort_with_93_patients_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24068121/ DB - PRIME DP - Unbound Medicine ER -