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[The correlation studies between recurrent otitis media and adenoid hypertrophy in children].
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Jul; 27(13):722-5.LC

Abstract

OBJECTIVE

To investigate the relationship between the immune status of adenoids and secretory otitis media (SOM).

METHOD

The adenoids tissue samples of 30 cases of recurrent secretory otitis media (SOM), 17 cases of non-recurrent secretory otitis media and 20 cases of the adenoids hypertrophy without SOM were studied by immunohistochemical method.

RESULT

The expression of PCNA, BCL-2, CD4+, CD8+ cells and CD4+/CD8+ in recurrent SOM tissue were 30.85 +/- 1.73, 21.27 +/- 1.25, 41.90 +/- 9.07; 20.45 +/- 7.08 and 2.10 +/- 0.17, respectively, which was remarkably higher than those of non-recurrent SOM, (25.50 +/- 1.66, 14.23 +/- 1.06, 17.40 +/- 6.85, 13.02 +/- 5.88, 1.33 +/- 0.11, respectively) and those of simple adenoid hypertrophy (25.25 +/- 1.75, 14.05 +/- 1.02, 16.30 +/- 8.21, 11.15 +/- 5.71 and 1.39 +/- 0.15, respectively) (P < 0.01); the difference of the expression of PCNA, BCL-2, CD4+, CD8+ and CD4+/CD8+ between the latter two groups was not significant. Differences of the gender or the size were not significant (P > 0.05). In group of simple adenoid hypertrophy, PCNA in the subgroup of the age 3 to 6 was significantly higher than those in the other groups (P < 0.05).

CONCLUSION

In adenoid tissues of recurrent SOM patients, the activities of T-lymphocyte subsets cells in hypertrophic status increase, the adenoids enlarge and local immunity enhances. The age and gender have nothing to do with the SOM, but low age is one of the influencing factors of adenoid hypertrophy. Therefore, adenoidectomy for recurrent SOM patients with adenoid hypertrophy should be carried out as early as possible.

Authors+Show Affiliations

Liu W
Department of Otorhinolaryngology, Cangzhou Central Hospital, Cangzhou 061000, China.
Zhang S
No affiliation info available
Zhang Y
No affiliation info available
Yue Z
No affiliation info available
Yin G
No affiliation info available

MeSH

AdenoidsAdolescentCD8-Positive T-LymphocytesChildChild, PreschoolFemaleFlow CytometryHumansHypertrophyMaleOtitis Media with Effusion

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

24073583

Citation

Liu, Weiwei, et al. "[The Correlation Studies Between Recurrent Otitis Media and Adenoid Hypertrophy in Children]." Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery, vol. 27, no. 13, 2013, pp. 722-5.
Liu W, Zhang S, Zhang Y, et al. [The correlation studies between recurrent otitis media and adenoid hypertrophy in children]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013;27(13):722-5.
Liu, W., Zhang, S., Zhang, Y., Yue, Z., & Yin, G. (2013). [The correlation studies between recurrent otitis media and adenoid hypertrophy in children]. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi = Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery, 27(13), 722-5.
Liu W, et al. [The Correlation Studies Between Recurrent Otitis Media and Adenoid Hypertrophy in Children]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013;27(13):722-5. PubMed PMID: 24073583.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The correlation studies between recurrent otitis media and adenoid hypertrophy in children]. AU - Liu,Weiwei, AU - Zhang,Shujun, AU - Zhang,Yuli, AU - Yue,Zhuoli, AU - Yin,Guiru, PY - 2013/10/1/entrez PY - 2013/10/1/pubmed PY - 2014/1/24/medline SP - 722 EP - 5 JF - Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery JO - Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi VL - 27 IS - 13 N2 - OBJECTIVE: To investigate the relationship between the immune status of adenoids and secretory otitis media (SOM). METHOD: The adenoids tissue samples of 30 cases of recurrent secretory otitis media (SOM), 17 cases of non-recurrent secretory otitis media and 20 cases of the adenoids hypertrophy without SOM were studied by immunohistochemical method. RESULT: The expression of PCNA, BCL-2, CD4+, CD8+ cells and CD4+/CD8+ in recurrent SOM tissue were 30.85 +/- 1.73, 21.27 +/- 1.25, 41.90 +/- 9.07; 20.45 +/- 7.08 and 2.10 +/- 0.17, respectively, which was remarkably higher than those of non-recurrent SOM, (25.50 +/- 1.66, 14.23 +/- 1.06, 17.40 +/- 6.85, 13.02 +/- 5.88, 1.33 +/- 0.11, respectively) and those of simple adenoid hypertrophy (25.25 +/- 1.75, 14.05 +/- 1.02, 16.30 +/- 8.21, 11.15 +/- 5.71 and 1.39 +/- 0.15, respectively) (P < 0.01); the difference of the expression of PCNA, BCL-2, CD4+, CD8+ and CD4+/CD8+ between the latter two groups was not significant. Differences of the gender or the size were not significant (P > 0.05). In group of simple adenoid hypertrophy, PCNA in the subgroup of the age 3 to 6 was significantly higher than those in the other groups (P < 0.05). CONCLUSION: In adenoid tissues of recurrent SOM patients, the activities of T-lymphocyte subsets cells in hypertrophic status increase, the adenoids enlarge and local immunity enhances. The age and gender have nothing to do with the SOM, but low age is one of the influencing factors of adenoid hypertrophy. Therefore, adenoidectomy for recurrent SOM patients with adenoid hypertrophy should be carried out as early as possible. SN - 2096-7993 UR - https://www.unboundmedicine.com/medline/citation/24073583/[The_correlation_studies_between_recurrent_otitis_media_and_adenoid_hypertrophy_in_children]_ L2 - https://medlineplus.gov/adenoids.html DB - PRIME DP - Unbound Medicine ER -