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Yellow fever vaccination: is one dose always enough?
Travel Med Infect Dis. 2013 Sep-Oct; 11(5):266-73.TM

Abstract

In March 2013, the World Health Organization (WHO) Strategic Advisory Group of Experts on Immunisation (SAGE) considered a number of issues in order to update the WHO Position Paper on Yellow Fever (2003). A key conclusion of this review was that a single dose of yellow fever (YF) vaccine appears to confer life-long protection against YF disease, and that a booster dose of YF vaccine is not needed to maintain immunity. While the efficacy of YF vaccine in the majority of vaccine recipients is not in doubt, the WHO announcement is somewhat surprising as there are some limitations in the evidence base, but more importantly, this announcement is not accompanied by any imminent change in the International Health Regulations 2005. The tension between what is considered best clinical practice and the law will be difficult to reconcile for many health professionals, travellers, and the travel industry, in an area of travel medicine that is already subject to debate and confusion. This commentary reviews the recent WHO announcement, and considers the practical implications for health professionals providing YF vaccine to international travellers.

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Authors+Show Affiliations

Patel D
National Travel Health Network and Centre, London, UK; Foreign and Commonwealth Office, London, UK; Centre for Occupational and Environmental Health, School of Medicine, The University of Manchester, Manchester, UK. Electronic address: dipti.patel@uclh.nhs.uk.
Simons H
No affiliation info available

MeSH

AfricaHumansImmunization ScheduleImmunization, SecondarySouth AmericaTravel MedicineYellow FeverYellow Fever Vaccine

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

24074827

Citation

Patel, Dipti, and Hilary Simons. "Yellow Fever Vaccination: Is One Dose Always Enough?" Travel Medicine and Infectious Disease, vol. 11, no. 5, 2013, pp. 266-73.
Patel D, Simons H. Yellow fever vaccination: is one dose always enough? Travel Med Infect Dis. 2013;11(5):266-73.
Patel, D., & Simons, H. (2013). Yellow fever vaccination: is one dose always enough? Travel Medicine and Infectious Disease, 11(5), 266-73. https://doi.org/10.1016/j.tmaid.2013.08.007
Patel D, Simons H. Yellow Fever Vaccination: Is One Dose Always Enough. Travel Med Infect Dis. 2013 Sep-Oct;11(5):266-73. PubMed PMID: 24074827.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Yellow fever vaccination: is one dose always enough? AU - Patel,Dipti, AU - Simons,Hilary, Y1 - 2013/09/05/ PY - 2013/08/17/received PY - 2013/08/29/revised PY - 2013/08/29/accepted PY - 2013/10/1/entrez PY - 2013/10/1/pubmed PY - 2014/6/4/medline KW - Booster KW - Immunity KW - International Health Regulations KW - Vaccine efficacy SP - 266 EP - 73 JF - Travel medicine and infectious disease JO - Travel Med Infect Dis VL - 11 IS - 5 N2 - In March 2013, the World Health Organization (WHO) Strategic Advisory Group of Experts on Immunisation (SAGE) considered a number of issues in order to update the WHO Position Paper on Yellow Fever (2003). A key conclusion of this review was that a single dose of yellow fever (YF) vaccine appears to confer life-long protection against YF disease, and that a booster dose of YF vaccine is not needed to maintain immunity. While the efficacy of YF vaccine in the majority of vaccine recipients is not in doubt, the WHO announcement is somewhat surprising as there are some limitations in the evidence base, but more importantly, this announcement is not accompanied by any imminent change in the International Health Regulations 2005. The tension between what is considered best clinical practice and the law will be difficult to reconcile for many health professionals, travellers, and the travel industry, in an area of travel medicine that is already subject to debate and confusion. This commentary reviews the recent WHO announcement, and considers the practical implications for health professionals providing YF vaccine to international travellers. SN - 1873-0442 UR - https://www.unboundmedicine.com/medline/citation/24074827/Yellow_fever_vaccination:_is_one_dose_always_enough L2 - https://linkinghub.elsevier.com/retrieve/pii/S1477-8939(13)00136-1 DB - PRIME DP - Unbound Medicine ER -