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Physical activity and risk of hypertension: a meta-analysis of prospective cohort studies.
Hypertension 2013; 62(6):1021-6H

Abstract

Published literature reports controversial results about the association of physical activity (PA) with risk of hypertension. A meta-analysis of prospective cohort studies was performed to investigate the effect of PA on hypertension risk. PubMed and Embase databases were searched to identify all related prospective cohort studies. The Q test and I(2) statistic were used to examine between-study heterogeneity. Fixed or random effects models were selected based on study heterogeneity. A funnel plot and modified Egger linear regression test were used to estimate publication bias. Thirteen prospective cohort studies were identified, including 136,846 persons who were initially free of hypertension, and 15,607 persons developed hypertension during follow-up. The pooled relative risk (RR) of main results from these studies suggests that both high and moderate levels of recreational PA were associated with decreased risk of hypertension (high versus low: RR, 0.81; 95% confidence interval, 0.76-0.85 and moderate versus low: RR, 0.89; 95% confidence interval, 0.85-0.94). The association of high or moderate occupational PA with decreased hypertension risk was not significant (high versus low: RR, 0.93; 95% confidence interval, 0.81-1.08 and moderate versus low: RR, 0.96; 95% confidence interval, 0.87-1.06). No publication bias was observed. The results of this meta-analysis suggested that there was an inverse dose-response association between levels of recreational PA and risk of hypertension, whereas there was no significant association between occupational PA and hypertension.

Authors+Show Affiliations

Department of Epidemiology and Health Statistics, School of Public Health, Shandong University, 44 Wenhuaxi Rd, Jinan 250012, China. weima@sdu.edu.cn; or Bo Xi, Department of Maternal and Child Health, School of Public Health, Shandong University, 44 Wenhuaxi Rd, Jinan 250012, China. E-mail xibo2010@sdu.edu.cn.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24082054

Citation

Huai, Pengcheng, et al. "Physical Activity and Risk of Hypertension: a Meta-analysis of Prospective Cohort Studies." Hypertension (Dallas, Tex. : 1979), vol. 62, no. 6, 2013, pp. 1021-6.
Huai P, Xun H, Reilly KH, et al. Physical activity and risk of hypertension: a meta-analysis of prospective cohort studies. Hypertension. 2013;62(6):1021-6.
Huai, P., Xun, H., Reilly, K. H., Wang, Y., Ma, W., & Xi, B. (2013). Physical activity and risk of hypertension: a meta-analysis of prospective cohort studies. Hypertension (Dallas, Tex. : 1979), 62(6), pp. 1021-6. doi:10.1161/HYPERTENSIONAHA.113.01965.
Huai P, et al. Physical Activity and Risk of Hypertension: a Meta-analysis of Prospective Cohort Studies. Hypertension. 2013;62(6):1021-6. PubMed PMID: 24082054.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Physical activity and risk of hypertension: a meta-analysis of prospective cohort studies. AU - Huai,Pengcheng, AU - Xun,Huanmiao, AU - Reilly,Kathleen Heather, AU - Wang,Yiguan, AU - Ma,Wei, AU - Xi,Bo, Y1 - 2013/09/30/ PY - 2013/10/2/entrez PY - 2013/10/2/pubmed PY - 2014/1/1/medline KW - cohort studies KW - hypertension KW - meta-analysis KW - motor activity SP - 1021 EP - 6 JF - Hypertension (Dallas, Tex. : 1979) JO - Hypertension VL - 62 IS - 6 N2 - Published literature reports controversial results about the association of physical activity (PA) with risk of hypertension. A meta-analysis of prospective cohort studies was performed to investigate the effect of PA on hypertension risk. PubMed and Embase databases were searched to identify all related prospective cohort studies. The Q test and I(2) statistic were used to examine between-study heterogeneity. Fixed or random effects models were selected based on study heterogeneity. A funnel plot and modified Egger linear regression test were used to estimate publication bias. Thirteen prospective cohort studies were identified, including 136,846 persons who were initially free of hypertension, and 15,607 persons developed hypertension during follow-up. The pooled relative risk (RR) of main results from these studies suggests that both high and moderate levels of recreational PA were associated with decreased risk of hypertension (high versus low: RR, 0.81; 95% confidence interval, 0.76-0.85 and moderate versus low: RR, 0.89; 95% confidence interval, 0.85-0.94). The association of high or moderate occupational PA with decreased hypertension risk was not significant (high versus low: RR, 0.93; 95% confidence interval, 0.81-1.08 and moderate versus low: RR, 0.96; 95% confidence interval, 0.87-1.06). No publication bias was observed. The results of this meta-analysis suggested that there was an inverse dose-response association between levels of recreational PA and risk of hypertension, whereas there was no significant association between occupational PA and hypertension. SN - 1524-4563 UR - https://www.unboundmedicine.com/medline/citation/24082054/full_citation L2 - http://www.ahajournals.org/doi/full/10.1161/HYPERTENSIONAHA.113.01965?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -