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Alcohol Consumption and Breast Cancer Survival: A Meta- analysis of Cohort Studies.
Asian Pac J Cancer Prev 2013; 14(8):4785-90AP

Abstract

BACKGROUND AND OBJECTIVES

Evidence for associations between alcohol consumption with breast cancer survival are conflicting, so we conducted the present meta-analysis.

METHODS

Comprehensive searches were conducted to find cohort studies that evaluated the relationship between alcohol consumption with breast cancer survival. Data were analyzed with meta-analysis software.

RESULTS

We included 25 cohort studies. The meta-analysis results showed that alcohol consumption was not associated with increased breast cancer mortality and recurrence after pooling all data from highest versus lowest comparisons. Subgroup analyses showed that pre-diagnostic or post-diagnostic consumpotion, and ER status did not affect the relationship with breast cancer mortality and recurrence. Although the relationships of different alcohol consumption with breast cancer mortality and recurrence were not significant, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence. Only alcohol consumption of >20 g/d was associated with increased breast cancer mortality, but not with increased breast cancer recurrence.

CONCLUSION

Although our meta-analysis showed alcohol drinking was not associated with increased breast cancer mortality and recurrence, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence and alcohol consumption of >20 g/d was associated with increased breast cancer mortality.

Authors+Show Affiliations

Department of Thoracic Surgery, Lanzhou University, Second Hospital, Lanzhou, Gansu Province, China E-mail : hexiaodong2006@126.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis

Language

eng

PubMed ID

24083744

Citation

Gou, Yun-Jiu, et al. "Alcohol Consumption and Breast Cancer Survival: a Meta- Analysis of Cohort Studies." Asian Pacific Journal of Cancer Prevention : APJCP, vol. 14, no. 8, 2013, pp. 4785-90.
Gou YJ, Xie DX, Yang KH, et al. Alcohol Consumption and Breast Cancer Survival: A Meta- analysis of Cohort Studies. Asian Pac J Cancer Prev. 2013;14(8):4785-90.
Gou, Y. J., Xie, D. X., Yang, K. H., Liu, Y. L., Zhang, J. H., Li, B., & He, X. D. (2013). Alcohol Consumption and Breast Cancer Survival: A Meta- analysis of Cohort Studies. Asian Pacific Journal of Cancer Prevention : APJCP, 14(8), pp. 4785-90.
Gou YJ, et al. Alcohol Consumption and Breast Cancer Survival: a Meta- Analysis of Cohort Studies. Asian Pac J Cancer Prev. 2013;14(8):4785-90. PubMed PMID: 24083744.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol Consumption and Breast Cancer Survival: A Meta- analysis of Cohort Studies. AU - Gou,Yun-Jiu, AU - Xie,Ding-Xiong, AU - Yang,Ke-Hu, AU - Liu,Ya-Li, AU - Zhang,Jian-Hua, AU - Li,Bin, AU - He,Xiao-Dong, PY - 2013/10/3/entrez PY - 2013/10/3/pubmed PY - 2014/5/16/medline SP - 4785 EP - 90 JF - Asian Pacific journal of cancer prevention : APJCP JO - Asian Pac. J. Cancer Prev. VL - 14 IS - 8 N2 - BACKGROUND AND OBJECTIVES: Evidence for associations between alcohol consumption with breast cancer survival are conflicting, so we conducted the present meta-analysis. METHODS: Comprehensive searches were conducted to find cohort studies that evaluated the relationship between alcohol consumption with breast cancer survival. Data were analyzed with meta-analysis software. RESULTS: We included 25 cohort studies. The meta-analysis results showed that alcohol consumption was not associated with increased breast cancer mortality and recurrence after pooling all data from highest versus lowest comparisons. Subgroup analyses showed that pre-diagnostic or post-diagnostic consumpotion, and ER status did not affect the relationship with breast cancer mortality and recurrence. Although the relationships of different alcohol consumption with breast cancer mortality and recurrence were not significant, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence. Only alcohol consumption of >20 g/d was associated with increased breast cancer mortality, but not with increased breast cancer recurrence. CONCLUSION: Although our meta-analysis showed alcohol drinking was not associated with increased breast cancer mortality and recurrence, there seemed to be a dose-response relationship of alcohol consumption with breast cancer mortality and recurrence and alcohol consumption of >20 g/d was associated with increased breast cancer mortality. SN - 2476-762X UR - https://www.unboundmedicine.com/medline/citation/24083744/Alcohol_Consumption_and_Breast_Cancer_Survival:_A_Meta__analysis_of_Cohort_Studies_ L2 - http://journal.waocp.org/?sid=Entrez:PubMed&id=pmid:24083744&key=2013.14.8.4785 DB - PRIME DP - Unbound Medicine ER -