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Schistosomiasis combined with colorectal carcinoma diagnosed based on endoscopic findings and clinicopathological characteristics: a report on 32 cases.
Asian Pac J Cancer Prev. 2013; 14(8):4839-42.AP

Abstract

AIMS AND BACKGROUND

To improve understanding of the relationship between schistosome-related enteropathy and colorectal carcinoma with particular focus on endoscopic findings and clinicopathological characteristics of colonic schistosomiasis.

MATERIALS AND METHODS

All cases of intestinal schistosomiasis diagnosed at West China Hospital, Chengdu, China, between October 2006 and October 2012 were included in this study. A total of 179 cases of colonic schistosomiasis diagnosed through colonoscopy and pathological examinations were collected for analysis and the demographics, symptoms, endoscopic findings and clinicopathological characteristics were retrospectively evaluated.

RESULTS

Of the 179 colonic schistosomiasis patients, 32 combined with colorectal cancer (CRC) were found, between the ages of 44 and 85 years (24 males, 75%). These 32 lesions were classified as 12 endophytic/ulcerative (37.5%), 10 exophytic/fungating (31.2%), 4 annular (12.5%), 3 giant polypus (9.4%), and 3 IIc (superficial depressed type) (9.4%). The segments of rectum and sigmoid colon were involved in 19 patients (59.4%) and 6 patients (18.8%), respectively. The histopathologic types were classified as follows: 30 well- differentiated adenocarcinomas, one mucinous adenocarcinoma and one poorly differentiated adenocarcinoma. The pathological findings suggest colorectal malignancy with deposited schistosome ova.

CONCLUSIONS

Chronic schistosomal infestation has a probable etiological role in promoting genesis of colorectal neoplasms.

Authors+Show Affiliations

Digestive Endoscopy Center, Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, Sichuan, China E-mail : microsurgeon@gmail.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24083755

Citation

Liu, Wei, et al. "Schistosomiasis Combined With Colorectal Carcinoma Diagnosed Based On Endoscopic Findings and Clinicopathological Characteristics: a Report On 32 Cases." Asian Pacific Journal of Cancer Prevention : APJCP, vol. 14, no. 8, 2013, pp. 4839-42.
Liu W, Zeng HZ, Wang QM, et al. Schistosomiasis combined with colorectal carcinoma diagnosed based on endoscopic findings and clinicopathological characteristics: a report on 32 cases. Asian Pac J Cancer Prev. 2013;14(8):4839-42.
Liu, W., Zeng, H. Z., Wang, Q. M., Yi, H., Mou, Y., Wu, C. C., Hu, B., & Tang, C. W. (2013). Schistosomiasis combined with colorectal carcinoma diagnosed based on endoscopic findings and clinicopathological characteristics: a report on 32 cases. Asian Pacific Journal of Cancer Prevention : APJCP, 14(8), 4839-42.
Liu W, et al. Schistosomiasis Combined With Colorectal Carcinoma Diagnosed Based On Endoscopic Findings and Clinicopathological Characteristics: a Report On 32 Cases. Asian Pac J Cancer Prev. 2013;14(8):4839-42. PubMed PMID: 24083755.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Schistosomiasis combined with colorectal carcinoma diagnosed based on endoscopic findings and clinicopathological characteristics: a report on 32 cases. AU - Liu,Wei, AU - Zeng,Hong-Ze, AU - Wang,Qi-Ming, AU - Yi,Hang, AU - Mou,Yi, AU - Wu,Chun-Cheng, AU - Hu,Bing, AU - Tang,Cheng-Wei, PY - 2013/10/3/entrez PY - 2013/10/3/pubmed PY - 2014/5/16/medline SP - 4839 EP - 42 JF - Asian Pacific journal of cancer prevention : APJCP JO - Asian Pac. J. Cancer Prev. VL - 14 IS - 8 N2 - AIMS AND BACKGROUND: To improve understanding of the relationship between schistosome-related enteropathy and colorectal carcinoma with particular focus on endoscopic findings and clinicopathological characteristics of colonic schistosomiasis. MATERIALS AND METHODS: All cases of intestinal schistosomiasis diagnosed at West China Hospital, Chengdu, China, between October 2006 and October 2012 were included in this study. A total of 179 cases of colonic schistosomiasis diagnosed through colonoscopy and pathological examinations were collected for analysis and the demographics, symptoms, endoscopic findings and clinicopathological characteristics were retrospectively evaluated. RESULTS: Of the 179 colonic schistosomiasis patients, 32 combined with colorectal cancer (CRC) were found, between the ages of 44 and 85 years (24 males, 75%). These 32 lesions were classified as 12 endophytic/ulcerative (37.5%), 10 exophytic/fungating (31.2%), 4 annular (12.5%), 3 giant polypus (9.4%), and 3 IIc (superficial depressed type) (9.4%). The segments of rectum and sigmoid colon were involved in 19 patients (59.4%) and 6 patients (18.8%), respectively. The histopathologic types were classified as follows: 30 well- differentiated adenocarcinomas, one mucinous adenocarcinoma and one poorly differentiated adenocarcinoma. The pathological findings suggest colorectal malignancy with deposited schistosome ova. CONCLUSIONS: Chronic schistosomal infestation has a probable etiological role in promoting genesis of colorectal neoplasms. SN - 2476-762X UR - https://www.unboundmedicine.com/medline/citation/24083755/Schistosomiasis_combined_with_colorectal_carcinoma_diagnosed_based_on_endoscopic_findings_and_clinicopathological_characteristics:_a_report_on_32_cases_ L2 - http://journal.waocp.org/?sid=Entrez:PubMed&id=pmid:24083755&key=2013.14.8.4839 DB - PRIME DP - Unbound Medicine ER -