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Pituitary apoplexy induced by Gonadotropin-releasing hormone agonists for treating prostate cancer-report of first Asian case.
World J Surg Oncol. 2013 Oct 02; 11:254.WJ

Abstract

We present the first Asian case of a 77-year-old man who developed pituitary apoplexy (PA) soon after gonadotropin-releasing hormone agonist (GnRHa) (leuprorelin) injection to treat prostate cancer. Headache, ophthalmoplegia, visual field deficit, nausea, and vomiting are the typical characteristics of pituitary apoplexy. Though the occurrence rate is rare, the consequence of this condition can vary from mild symptoms such as headache to life-threatening scenarios like conscious change. Magnetic resonance imaging is the best imaging modality to detect PA and sublabial trans-sphenoid pituitary tumor removal can resolve most of PA symptoms and is so far the best solution in consensus. We also review 11 previous reported cases receiving GnRHa for androgen deprivation therapy of prostate cancer, and hope to alert clinicians to use GnRHa with caution.

Authors+Show Affiliations

Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Tz-You 1st Road, Kaohsiung, Taiwan. juanuro@gmail.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

24088191

Citation

Huang, Tsung-Yi, et al. "Pituitary Apoplexy Induced By Gonadotropin-releasing Hormone Agonists for Treating Prostate Cancer-report of First Asian Case." World Journal of Surgical Oncology, vol. 11, 2013, p. 254.
Huang TY, Lin JP, Lieu AS, et al. Pituitary apoplexy induced by Gonadotropin-releasing hormone agonists for treating prostate cancer-report of first Asian case. World J Surg Oncol. 2013;11:254.
Huang, T. Y., Lin, J. P., Lieu, A. S., Chen, Y. T., Chen, H. S., Jang, M. Y., Shen, J. T., Wu, W. J., Huang, S. P., & Juan, Y. S. (2013). Pituitary apoplexy induced by Gonadotropin-releasing hormone agonists for treating prostate cancer-report of first Asian case. World Journal of Surgical Oncology, 11, 254. https://doi.org/10.1186/1477-7819-11-254
Huang TY, et al. Pituitary Apoplexy Induced By Gonadotropin-releasing Hormone Agonists for Treating Prostate Cancer-report of First Asian Case. World J Surg Oncol. 2013 Oct 2;11:254. PubMed PMID: 24088191.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pituitary apoplexy induced by Gonadotropin-releasing hormone agonists for treating prostate cancer-report of first Asian case. AU - Huang,Tsung-Yi, AU - Lin,Jih-Pin, AU - Lieu,Ann-Shung, AU - Chen,Yi-Ting, AU - Chen,Hung-Sheng, AU - Jang,Mei-Yu, AU - Shen,Jung-Tsung, AU - Wu,Wen-Jeng, AU - Huang,Shu-Pin, AU - Juan,Yung-Shun, Y1 - 2013/10/02/ PY - 2013/07/17/received PY - 2013/09/19/accepted PY - 2013/10/4/entrez PY - 2013/10/4/pubmed PY - 2014/8/1/medline SP - 254 EP - 254 JF - World journal of surgical oncology JO - World J Surg Oncol VL - 11 N2 - We present the first Asian case of a 77-year-old man who developed pituitary apoplexy (PA) soon after gonadotropin-releasing hormone agonist (GnRHa) (leuprorelin) injection to treat prostate cancer. Headache, ophthalmoplegia, visual field deficit, nausea, and vomiting are the typical characteristics of pituitary apoplexy. Though the occurrence rate is rare, the consequence of this condition can vary from mild symptoms such as headache to life-threatening scenarios like conscious change. Magnetic resonance imaging is the best imaging modality to detect PA and sublabial trans-sphenoid pituitary tumor removal can resolve most of PA symptoms and is so far the best solution in consensus. We also review 11 previous reported cases receiving GnRHa for androgen deprivation therapy of prostate cancer, and hope to alert clinicians to use GnRHa with caution. SN - 1477-7819 UR - https://www.unboundmedicine.com/medline/citation/24088191/Pituitary_apoplexy_induced_by_Gonadotropin_releasing_hormone_agonists_for_treating_prostate_cancer_report_of_first_Asian_case_ L2 - https://wjso.biomedcentral.com/articles/10.1186/1477-7819-11-254 DB - PRIME DP - Unbound Medicine ER -