Tags

Type your tag names separated by a space and hit enter

Lower urinary tract symptoms (LUTS) as a risk factor for depressive symptoms in elderly men: results from a large prospective study in Southern Chinese men.
PLoS One. 2013; 8(9):e76017.Plos

Abstract

A cross-sectional relationship between lower urinary tract symptoms (LUTS) and depressive symptoms was previously reported among Southern Chinese men; however, the temporal relationship was unclear. Our objective is to evaluate the temporal relationship between moderate to severe lower urinary tract symptoms and clinically significant depressive symptoms in elderly Chinese men aged 65 in a prospective manner. In a prospective cohort of 2,000 Chinese men aged 65 to 92 years in Hong Kong, we studied the association of having moderate to severe LUTS at baseline and having clinically relevant depressive symptoms at year 2 follow-up. After excluding men with prostate or bladder cancer or surgery (n = 20) and lost to follow-up (n = 254), data on 1,726 subjects were analyzed. LUTS were measured by the International Prostate Symptom score; and clinically relevant depressive symptoms were measured by the Geriatric Depression Scale. The multiple logistic regressions showed that the presence of moderate-to-severe LUTS at baseline were significantly associated with increased risk for being depressed at two-year follow-up, with adjustments for demographic, lifestyle, medical factors, weight status and stressful life events (OR = 2.97; CI: 1.70-5.20). Association remained significant with additional adjustments for baseline GDS score (OR = 1.88; CI: 1.03-3.41). LUTS are important risk factors in predicting the presence of clinically relevant depressive symptoms. In elderly men, increased awareness and possible screening are needed to detect the increased risk of clinically relevant depressive symptoms.

Authors+Show Affiliations

School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24098757

Citation

Chung, Roger Y., et al. "Lower Urinary Tract Symptoms (LUTS) as a Risk Factor for Depressive Symptoms in Elderly Men: Results From a Large Prospective Study in Southern Chinese Men." PloS One, vol. 8, no. 9, 2013, pp. e76017.
Chung RY, Leung JC, Chan DC, et al. Lower urinary tract symptoms (LUTS) as a risk factor for depressive symptoms in elderly men: results from a large prospective study in Southern Chinese men. PLoS ONE. 2013;8(9):e76017.
Chung, R. Y., Leung, J. C., Chan, D. C., Woo, J., Wong, C. K., & Wong, S. Y. (2013). Lower urinary tract symptoms (LUTS) as a risk factor for depressive symptoms in elderly men: results from a large prospective study in Southern Chinese men. PloS One, 8(9), e76017. https://doi.org/10.1371/journal.pone.0076017
Chung RY, et al. Lower Urinary Tract Symptoms (LUTS) as a Risk Factor for Depressive Symptoms in Elderly Men: Results From a Large Prospective Study in Southern Chinese Men. PLoS ONE. 2013;8(9):e76017. PubMed PMID: 24098757.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lower urinary tract symptoms (LUTS) as a risk factor for depressive symptoms in elderly men: results from a large prospective study in Southern Chinese men. AU - Chung,Roger Y, AU - Leung,Jason C S, AU - Chan,Dicken C C, AU - Woo,Jean, AU - Wong,Carmen K M, AU - Wong,Samuel Y S, Y1 - 2013/09/30/ PY - 2013/06/14/received PY - 2013/08/16/accepted PY - 2013/10/8/entrez PY - 2013/10/8/pubmed PY - 2014/6/17/medline SP - e76017 EP - e76017 JF - PloS one JO - PLoS ONE VL - 8 IS - 9 N2 - A cross-sectional relationship between lower urinary tract symptoms (LUTS) and depressive symptoms was previously reported among Southern Chinese men; however, the temporal relationship was unclear. Our objective is to evaluate the temporal relationship between moderate to severe lower urinary tract symptoms and clinically significant depressive symptoms in elderly Chinese men aged 65 in a prospective manner. In a prospective cohort of 2,000 Chinese men aged 65 to 92 years in Hong Kong, we studied the association of having moderate to severe LUTS at baseline and having clinically relevant depressive symptoms at year 2 follow-up. After excluding men with prostate or bladder cancer or surgery (n = 20) and lost to follow-up (n = 254), data on 1,726 subjects were analyzed. LUTS were measured by the International Prostate Symptom score; and clinically relevant depressive symptoms were measured by the Geriatric Depression Scale. The multiple logistic regressions showed that the presence of moderate-to-severe LUTS at baseline were significantly associated with increased risk for being depressed at two-year follow-up, with adjustments for demographic, lifestyle, medical factors, weight status and stressful life events (OR = 2.97; CI: 1.70-5.20). Association remained significant with additional adjustments for baseline GDS score (OR = 1.88; CI: 1.03-3.41). LUTS are important risk factors in predicting the presence of clinically relevant depressive symptoms. In elderly men, increased awareness and possible screening are needed to detect the increased risk of clinically relevant depressive symptoms. SN - 1932-6203 UR - https://www.unboundmedicine.com/medline/citation/24098757/Lower_urinary_tract_symptoms__LUTS__as_a_risk_factor_for_depressive_symptoms_in_elderly_men:_results_from_a_large_prospective_study_in_Southern_Chinese_men_ L2 - http://dx.plos.org/10.1371/journal.pone.0076017 DB - PRIME DP - Unbound Medicine ER -