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The effect of continuous intrathecal baclofen on sitting in children with severe cerebral palsy.
Eur J Paediatr Neurol. 2014 Jan; 18(1):45-9.EJ

Abstract

AIM

To investigate the effect of intrathecal baclofen (ITB) on sitting in children with cerebral palsy with severe spasticity; and identify potential sub-groups of patients at particular risk of deterioration.

METHOD

Twenty three children with cerebral palsy, mean age 10 yrs 10 mo were assessed before and after ITB treatment using the Sitting dimension of the Gross Motor Function Measure. Sitting prior to treatment was compared to sitting following ITB treatment in the same children. Exploration of sub groups was also attempted to investigate affects of ITB on sitting according to age and severity of motor impairment.

RESULTS

No significant difference was found in sitting before ITB treatment compared to sitting following insertion of an ITB pump (p = 0.09). No specific age group or classification of motor impairment demonstrated significant deterioration in sitting following ITB treatment.

CONCLUSION

Sitting does not improve or deteriorate in children following treatment with ITB, independent of age or severity of motor impairment.

Authors+Show Affiliations

Queens Medical Centre, Nottingham University Hospital, Nottingham, UK. Electronic address: natalie.gray@nuh.nhs.uk.Queens Medical Centre, Nottingham University Hospital, Nottingham, UK.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24100173

Citation

Gray, Natalie, and Michael Vloeberghs. "The Effect of Continuous Intrathecal Baclofen On Sitting in Children With Severe Cerebral Palsy." European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society, vol. 18, no. 1, 2014, pp. 45-9.
Gray N, Vloeberghs M. The effect of continuous intrathecal baclofen on sitting in children with severe cerebral palsy. Eur J Paediatr Neurol. 2014;18(1):45-9.
Gray, N., & Vloeberghs, M. (2014). The effect of continuous intrathecal baclofen on sitting in children with severe cerebral palsy. European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society, 18(1), 45-9. https://doi.org/10.1016/j.ejpn.2013.08.003
Gray N, Vloeberghs M. The Effect of Continuous Intrathecal Baclofen On Sitting in Children With Severe Cerebral Palsy. Eur J Paediatr Neurol. 2014;18(1):45-9. PubMed PMID: 24100173.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effect of continuous intrathecal baclofen on sitting in children with severe cerebral palsy. AU - Gray,Natalie, AU - Vloeberghs,Michael, Y1 - 2013/09/25/ PY - 2013/01/03/received PY - 2013/08/08/revised PY - 2013/08/19/accepted PY - 2013/10/9/entrez PY - 2013/10/9/pubmed PY - 2014/10/13/medline KW - Cerebral palsy KW - Intrathecal baclofen KW - Sitting KW - Spasticity SP - 45 EP - 9 JF - European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society JO - Eur. J. Paediatr. Neurol. VL - 18 IS - 1 N2 - AIM: To investigate the effect of intrathecal baclofen (ITB) on sitting in children with cerebral palsy with severe spasticity; and identify potential sub-groups of patients at particular risk of deterioration. METHOD: Twenty three children with cerebral palsy, mean age 10 yrs 10 mo were assessed before and after ITB treatment using the Sitting dimension of the Gross Motor Function Measure. Sitting prior to treatment was compared to sitting following ITB treatment in the same children. Exploration of sub groups was also attempted to investigate affects of ITB on sitting according to age and severity of motor impairment. RESULTS: No significant difference was found in sitting before ITB treatment compared to sitting following insertion of an ITB pump (p = 0.09). No specific age group or classification of motor impairment demonstrated significant deterioration in sitting following ITB treatment. CONCLUSION: Sitting does not improve or deteriorate in children following treatment with ITB, independent of age or severity of motor impairment. SN - 1532-2130 UR - https://www.unboundmedicine.com/medline/citation/24100173/The_effect_of_continuous_intrathecal_baclofen_on_sitting_in_children_with_severe_cerebral_palsy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1090-3798(13)00133-5 DB - PRIME DP - Unbound Medicine ER -