Tags

Type your tag names separated by a space and hit enter

Correlation between foveal cone outer segment tips line and visual recovery after epiretinal membrane surgery.
Invest Ophthalmol Vis Sci. 2013 Nov 05; 54(12):7302-8.IO

Abstract

PURPOSE

To determine whether there is a significant correlation between the integrity of the foveal microstructures and the best-corrected visual acuity (BCVA) after pars plana vitrectomy for epiretinal membrane (ERM) removal.

METHODS

This was a retrospective, interventional case series. Forty-six eyes of 45 patients with an ERM underwent vitrectomy. The foveal area was examined by spectral-domain-optical coherence tomography (SD-OCT) preoperatively and postoperatively. The correlation between the length of the photoreceptor cone outer segment tips (COST) line defect, the inner segment/outer segment junction (IS/OS) line defect, the external limiting membrane (ELM) line defect, and the BCVA was determined.

RESULTS

The length of the COST line defect was significantly correlated with the BCVA at postoperative 1, 3, 6, 9, and 12 months (P < 0.001 for all). Forward stepwise regression analyses showed that the postoperative BCVA was significantly correlated with the length of COST line defect (P < 0.001) but not with the IS/OS line and ELM line defects for up to 6 months. The preoperative length of the COST line defect was significantly correlated with the postoperative BCVA at 12 months (P = 0.005), but the lengths of the IS/OS line defect and ELM line defect were not. The factor that best predicted the postoperative BCVA was the length of the preoperative COST line defect (P = 0.04) but not the preoperative BCVA (P = 0.69).

CONCLUSIONS

The recovery of the foveal COST line defect is correlated with the BCVA after ERM surgery. The length of the preoperative COST line defect can predict the potential foveal function. (ClinicalTrials.gov number, NCT01549249.).

Links

Publisher Full Text

Authors+Show Affiliations

Itoh Y
Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan.
Inoue M
No affiliation info available
Rii T
No affiliation info available
Hirota K
No affiliation info available
Hirakata A
No affiliation info available

MeSH

AgedAged, 80 and overEpiretinal MembraneFemaleFovea CentralisHumansMaleMiddle AgedPrognosisRecovery of FunctionRegression AnalysisRetinal Photoreceptor Cell Inner SegmentRetinal Photoreceptor Cell Outer SegmentRetrospective StudiesTomography, Optical CoherenceVisual AcuityVitrectomy

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24106115

Clinical Trial Links

Clinical trial which this article describes

Citation

Itoh, Yuji, et al. "Correlation Between Foveal Cone Outer Segment Tips Line and Visual Recovery After Epiretinal Membrane Surgery." Investigative Ophthalmology & Visual Science, vol. 54, no. 12, 2013, pp. 7302-8.
Itoh Y, Inoue M, Rii T, et al. Correlation between foveal cone outer segment tips line and visual recovery after epiretinal membrane surgery. Invest Ophthalmol Vis Sci. 2013;54(12):7302-8.
Itoh, Y., Inoue, M., Rii, T., Hirota, K., & Hirakata, A. (2013). Correlation between foveal cone outer segment tips line and visual recovery after epiretinal membrane surgery. Investigative Ophthalmology & Visual Science, 54(12), 7302-8. https://doi.org/10.1167/iovs.13-12702
Itoh Y, et al. Correlation Between Foveal Cone Outer Segment Tips Line and Visual Recovery After Epiretinal Membrane Surgery. Invest Ophthalmol Vis Sci. 2013 Nov 5;54(12):7302-8. PubMed PMID: 24106115.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Correlation between foveal cone outer segment tips line and visual recovery after epiretinal membrane surgery. AU - Itoh,Yuji, AU - Inoue,Makoto, AU - Rii,Tosho, AU - Hirota,Kazunari, AU - Hirakata,Akito, Y1 - 2013/11/05/ PY - 2013/10/10/entrez PY - 2013/10/10/pubmed PY - 2013/12/24/medline KW - cone outer segment tips KW - idiopathic epiretinal membrane KW - inner segment/outer segment junction KW - pars plana vitrectomy KW - spectral-domain optical coherence tomography SP - 7302 EP - 8 JF - Investigative ophthalmology & visual science JO - Invest Ophthalmol Vis Sci VL - 54 IS - 12 N2 - PURPOSE: To determine whether there is a significant correlation between the integrity of the foveal microstructures and the best-corrected visual acuity (BCVA) after pars plana vitrectomy for epiretinal membrane (ERM) removal. METHODS: This was a retrospective, interventional case series. Forty-six eyes of 45 patients with an ERM underwent vitrectomy. The foveal area was examined by spectral-domain-optical coherence tomography (SD-OCT) preoperatively and postoperatively. The correlation between the length of the photoreceptor cone outer segment tips (COST) line defect, the inner segment/outer segment junction (IS/OS) line defect, the external limiting membrane (ELM) line defect, and the BCVA was determined. RESULTS: The length of the COST line defect was significantly correlated with the BCVA at postoperative 1, 3, 6, 9, and 12 months (P < 0.001 for all). Forward stepwise regression analyses showed that the postoperative BCVA was significantly correlated with the length of COST line defect (P < 0.001) but not with the IS/OS line and ELM line defects for up to 6 months. The preoperative length of the COST line defect was significantly correlated with the postoperative BCVA at 12 months (P = 0.005), but the lengths of the IS/OS line defect and ELM line defect were not. The factor that best predicted the postoperative BCVA was the length of the preoperative COST line defect (P = 0.04) but not the preoperative BCVA (P = 0.69). CONCLUSIONS: The recovery of the foveal COST line defect is correlated with the BCVA after ERM surgery. The length of the preoperative COST line defect can predict the potential foveal function. (ClinicalTrials.gov number, NCT01549249.). SN - 1552-5783 UR - https://www.unboundmedicine.com/medline/citation/24106115/Correlation_between_foveal_cone_outer_segment_tips_line_and_visual_recovery_after_epiretinal_membrane_surgery_ L2 - https://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.13-12702 DB - PRIME DP - Unbound Medicine ER -