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Probiotics and irritable bowel syndrome.
World J Gastroenterol. 2013 Sep 28; 19(36):5973-80.WJ

Abstract

Irritable bowel syndrome (IBS) is common gastrointestinal problems. It is characterized by abdominal pain or discomfort, and is associated with changes in stool frequency and/or consistency. The etiopathogenesis of IBS may be multifactorial, as is the pathophysiology, which is attributed to alterations in gastrointestinal motility, visceral hypersensitivity, intestinal microbiota, gut epithelium and immune function, dysfunction of the brain-gut axis or certain psychosocial factors. Current therapeutic strategies are often unsatisfactory. There is now increasing evidence linking alterations in the gastrointestinal microbiota and IBS. Probiotics are living organisms which, when ingested in certain numbers, exert health benefits beyond inherent basic nutrition. Probiotics have numerous positive effects in the gastrointestinal tract. Recently, many studies have suggested that probiotics are effective in the treatment of IBS. The mechanisms of probiotics in IBS are very complex. The purpose of this review is to summarize the evidence and mechanisms for the use of probiotics in the treatment of IBS.

Authors+Show Affiliations

Cong Dai, Xiao-Yu Ma, Li-Juan Jiang, Department of Cadre Ward V, First Affiliated Hospital, China Medical University, Shenyang 110001, Liaoning Province, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

24106397

Citation

Dai, Cong, et al. "Probiotics and Irritable Bowel Syndrome." World Journal of Gastroenterology, vol. 19, no. 36, 2013, pp. 5973-80.
Dai C, Zheng CQ, Jiang M, et al. Probiotics and irritable bowel syndrome. World J Gastroenterol. 2013;19(36):5973-80.
Dai, C., Zheng, C. Q., Jiang, M., Ma, X. Y., & Jiang, L. J. (2013). Probiotics and irritable bowel syndrome. World Journal of Gastroenterology, 19(36), 5973-80. https://doi.org/10.3748/wjg.v19.i36.5973
Dai C, et al. Probiotics and Irritable Bowel Syndrome. World J Gastroenterol. 2013 Sep 28;19(36):5973-80. PubMed PMID: 24106397.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Probiotics and irritable bowel syndrome. AU - Dai,Cong, AU - Zheng,Chang-Qing, AU - Jiang,Min, AU - Ma,Xiao-Yu, AU - Jiang,Li-Juan, PY - 2013/05/23/received PY - 2013/07/14/revised PY - 2013/08/04/accepted PY - 2013/10/10/entrez PY - 2013/10/10/pubmed PY - 2014/3/14/medline KW - Brain-gut axis KW - Immune function KW - Irritable bowel syndrome KW - Probiotics KW - Visceral hypersensitivity SP - 5973 EP - 80 JF - World journal of gastroenterology JO - World J Gastroenterol VL - 19 IS - 36 N2 - Irritable bowel syndrome (IBS) is common gastrointestinal problems. It is characterized by abdominal pain or discomfort, and is associated with changes in stool frequency and/or consistency. The etiopathogenesis of IBS may be multifactorial, as is the pathophysiology, which is attributed to alterations in gastrointestinal motility, visceral hypersensitivity, intestinal microbiota, gut epithelium and immune function, dysfunction of the brain-gut axis or certain psychosocial factors. Current therapeutic strategies are often unsatisfactory. There is now increasing evidence linking alterations in the gastrointestinal microbiota and IBS. Probiotics are living organisms which, when ingested in certain numbers, exert health benefits beyond inherent basic nutrition. Probiotics have numerous positive effects in the gastrointestinal tract. Recently, many studies have suggested that probiotics are effective in the treatment of IBS. The mechanisms of probiotics in IBS are very complex. The purpose of this review is to summarize the evidence and mechanisms for the use of probiotics in the treatment of IBS. SN - 2219-2840 UR - https://www.unboundmedicine.com/medline/citation/24106397/Probiotics_and_irritable_bowel_syndrome_ L2 - https://www.wjgnet.com/1007-9327/full/v19/i36/5973.htm DB - PRIME DP - Unbound Medicine ER -