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Clinical profile of isolated viral anterior uveitis in a South Indian patient population.
Ocul Immunol Inflamm. 2014 Oct; 22(5):356-9.OI

Abstract

AIM

To analyze the clinic profile of polymerase chain reaction proven viral anterior uveitis in a south Indian patient population.

MATERIALS & METHODS

Retrospective, nonrandomized study between January 2009 and July 2012.

RESULTS

Out of the 36 patients with polymerase chain reaction (PCR)-positive viral anterior uveitis, 24 patients had varicella zoster virus (VZV) anterior uveitis, 7 patients had HSV anterior uveitis, 3 patients had cytomegalovirus (CMV) anterior uveitis, and 2 patients had chikungunya virus related anterior uveitis. Corneal involvement was seen in 21 cases (58.33%). An altered iris pattern was seen in 14 cases (38.89%). Increase in intraocular pressure (IOP) at the time of inflammation was seen in 10 cases (27.78%). Reactivations were seen in 22 cases (61.11%). A comparison of herpes simplex virus (HSV)- and VZV-related anterior uveitis did not reveal any significant factors except for a previous history of herpes zoster in VZV-associated uveitis.

CONCLUSION

We see isolated viral anterior uveitis related to HSV, VZV, CMV, and chikungunya viruses in our patient population. Corneal involvement, pigmented keratic precipitates, an abnormal iris pattern, increase in IOP, and reactivations are seen as a spectrum of viral anterior uveitis in our patient population as well.

Authors+Show Affiliations

Vittala International Institute of Ophthalmology & Prabha Eye Clinic and Research Center , Bangalore , India and.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

24111839

Citation

Babu, Kalpana, et al. "Clinical Profile of Isolated Viral Anterior Uveitis in a South Indian Patient Population." Ocular Immunology and Inflammation, vol. 22, no. 5, 2014, pp. 356-9.
Babu K, Kini R, Philips M, et al. Clinical profile of isolated viral anterior uveitis in a South Indian patient population. Ocul Immunol Inflamm. 2014;22(5):356-9.
Babu, K., Kini, R., Philips, M., & Subbakrishna, D. K. (2014). Clinical profile of isolated viral anterior uveitis in a South Indian patient population. Ocular Immunology and Inflammation, 22(5), 356-9. https://doi.org/10.3109/09273948.2013.841482
Babu K, et al. Clinical Profile of Isolated Viral Anterior Uveitis in a South Indian Patient Population. Ocul Immunol Inflamm. 2014;22(5):356-9. PubMed PMID: 24111839.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical profile of isolated viral anterior uveitis in a South Indian patient population. AU - Babu,Kalpana, AU - Kini,Raghuvir, AU - Philips,Mariamma, AU - Subbakrishna,D K, Y1 - 2013/10/10/ PY - 2013/10/12/entrez PY - 2013/10/12/pubmed PY - 2015/6/3/medline KW - Anterior uveitis KW - PCR KW - cytomegalovirus KW - herpes simplex KW - varicella zoster SP - 356 EP - 9 JF - Ocular immunology and inflammation JO - Ocul. Immunol. Inflamm. VL - 22 IS - 5 N2 - AIM: To analyze the clinic profile of polymerase chain reaction proven viral anterior uveitis in a south Indian patient population. MATERIALS & METHODS: Retrospective, nonrandomized study between January 2009 and July 2012. RESULTS: Out of the 36 patients with polymerase chain reaction (PCR)-positive viral anterior uveitis, 24 patients had varicella zoster virus (VZV) anterior uveitis, 7 patients had HSV anterior uveitis, 3 patients had cytomegalovirus (CMV) anterior uveitis, and 2 patients had chikungunya virus related anterior uveitis. Corneal involvement was seen in 21 cases (58.33%). An altered iris pattern was seen in 14 cases (38.89%). Increase in intraocular pressure (IOP) at the time of inflammation was seen in 10 cases (27.78%). Reactivations were seen in 22 cases (61.11%). A comparison of herpes simplex virus (HSV)- and VZV-related anterior uveitis did not reveal any significant factors except for a previous history of herpes zoster in VZV-associated uveitis. CONCLUSION: We see isolated viral anterior uveitis related to HSV, VZV, CMV, and chikungunya viruses in our patient population. Corneal involvement, pigmented keratic precipitates, an abnormal iris pattern, increase in IOP, and reactivations are seen as a spectrum of viral anterior uveitis in our patient population as well. SN - 1744-5078 UR - https://www.unboundmedicine.com/medline/citation/24111839/Clinical_profile_of_isolated_viral_anterior_uveitis_in_a_South_Indian_patient_population_ L2 - http://www.tandfonline.com/doi/full/10.3109/09273948.2013.841482 DB - PRIME DP - Unbound Medicine ER -