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A longitudinal study revealing hepatitis E virus infection and transmission at a swine test station.
Res Vet Sci. 2013 Dec; 95(3):1255-61.RV

Abstract

Hepatitis E virus (HEV) is a zoonotic agent that causes acute hepatitis in humans, and infects several animal species, most importantly swine. In the current study, that presents the first evidence of HEV infections in pigs in Finland, genetic divergence and transmission of HEV was investigated among pigs at a swine test station at two occasions. In 2007, HEV RNA was found in 25% of pens, and 35% of 2-3 month-old pigs at the station. Three different isolates, comprising 13 sequences of HEV genotype 3 e that were imported from different farms were detected. In 2010, 39% of pigs were HEV RNA positive on weeks 1, 3, or 5 of a 3-month follow-up, and 11 sequences, all representing one of the isolates that was also present in 2007, were detected. The isolate was considered to be either re-introduced to, or to persist at the station, and it was transmitted between the pigs. The study sheds light on the rate and time of HEV transmission in swine, and describes the epidemiologic variability of HEV isolates over time.

Authors+Show Affiliations

University of Helsinki, Faculty of Veterinary Medicine, Department of Food Hygiene and Environmental Health, P.O. Box 66, 00014 University of Helsinki, Finland. Electronic address: tuija.kantala@helsinki.fi.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24119762

Citation

Kantala, T, et al. "A Longitudinal Study Revealing Hepatitis E Virus Infection and Transmission at a Swine Test Station." Research in Veterinary Science, vol. 95, no. 3, 2013, pp. 1255-61.
Kantala T, Oristo S, Heinonen M, et al. A longitudinal study revealing hepatitis E virus infection and transmission at a swine test station. Res Vet Sci. 2013;95(3):1255-61.
Kantala, T., Oristo, S., Heinonen, M., von Bonsdorff, C. H., & Maunula, L. (2013). A longitudinal study revealing hepatitis E virus infection and transmission at a swine test station. Research in Veterinary Science, 95(3), 1255-61. https://doi.org/10.1016/j.rvsc.2013.09.006
Kantala T, et al. A Longitudinal Study Revealing Hepatitis E Virus Infection and Transmission at a Swine Test Station. Res Vet Sci. 2013;95(3):1255-61. PubMed PMID: 24119762.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A longitudinal study revealing hepatitis E virus infection and transmission at a swine test station. AU - Kantala,T, AU - Oristo,S, AU - Heinonen,M, AU - von Bonsdorff,C-H, AU - Maunula,L, Y1 - 2013/09/19/ PY - 2012/11/09/received PY - 2013/08/29/revised PY - 2013/09/07/accepted PY - 2013/10/15/entrez PY - 2013/10/15/pubmed PY - 2014/7/30/medline KW - Genotype 3e KW - HEV KW - Longitudinal study KW - Swine KW - Transmission SP - 1255 EP - 61 JF - Research in veterinary science JO - Res Vet Sci VL - 95 IS - 3 N2 - Hepatitis E virus (HEV) is a zoonotic agent that causes acute hepatitis in humans, and infects several animal species, most importantly swine. In the current study, that presents the first evidence of HEV infections in pigs in Finland, genetic divergence and transmission of HEV was investigated among pigs at a swine test station at two occasions. In 2007, HEV RNA was found in 25% of pens, and 35% of 2-3 month-old pigs at the station. Three different isolates, comprising 13 sequences of HEV genotype 3 e that were imported from different farms were detected. In 2010, 39% of pigs were HEV RNA positive on weeks 1, 3, or 5 of a 3-month follow-up, and 11 sequences, all representing one of the isolates that was also present in 2007, were detected. The isolate was considered to be either re-introduced to, or to persist at the station, and it was transmitted between the pigs. The study sheds light on the rate and time of HEV transmission in swine, and describes the epidemiologic variability of HEV isolates over time. SN - 1532-2661 UR - https://www.unboundmedicine.com/medline/citation/24119762/A_longitudinal_study_revealing_hepatitis_E_virus_infection_and_transmission_at_a_swine_test_station_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0034-5288(13)00306-8 DB - PRIME DP - Unbound Medicine ER -