Tags

Type your tag names separated by a space and hit enter

Screening for major and minor depression in a multiethnic sample of Asian primary care patients: a comparison of the nine-item Patient Health Questionnaire (PHQ-9) and the 16-item Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR16).
Asia Pac Psychiatry. 2013 Dec; 5(4):249-58.AP

Abstract

INTRODUCTION

Depression is common, disabling, and the single most important factor leading to suicide, yet it is underdiagnosed in busy primary care settings. A key challenge facing primary care clinicians in Asia is the selection of instruments to facilitate depression screening. Although the nine-item Patient Health Questionnaire (PHQ-9) and 16-item Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR16) are used internationally, they have not been directly compared or widely validated in Asian primary care populations. This study aimed to validate the PHQ-9 and QIDS-SR16 against a structured interview diagnosis of Diagnostic and Statistical Manual, 4th Edition, depression based on the Mini-International Neuropsychiatric Interview in a multiethnic Asian sample.

METHODS

From April through August 2011, we enrolled 400 English-speaking Singaporean primary care patients. Participants completed a demographic data form, the PHQ-9, and the QIDS-SR16 . They were assessed independently for major and minor depression using the Mini-International Neuropsychiatric Interview.

RESULTS

Sensitivity and specificity for diagnosing major depression were 91.7% and 72.2%, respectively, for the PHQ-9 (optimal cutoff score of 6), and 83.3% and 84.7%, respectively, for the QIDS-SR16 (optimal cutoff score of 9). The QIDS-SR16 also detected minor depression at an optimal cutoff score of 7, with a sensitivity of 94.4% and specificity of 77.9%. The PHQ-9 and QIDS-SR16 showed good internal consistency (Cronbach's α: 0.87 and 0.79, respectively) and good convergent validity (correlation coefficient: r = 0.73, P < 0.001). The overall prevalence of major and minor depressive disorders was 9%.

DISCUSSION

The PHQ-9 and QIDS-SR16 appear to be valid and reliable for depression screening in Asian primary care settings.

Authors+Show Affiliations

Office of Clinical Sciences, Duke-NUS Graduate Medical School Singapore, Singapore; Department of Child & Adolescent Psychiatry, Institute of Mental Health, Singapore.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Validation Study

Language

eng

PubMed ID

24123813

Citation

Sung, Sharon Cohan, et al. "Screening for Major and Minor Depression in a Multiethnic Sample of Asian Primary Care Patients: a Comparison of the Nine-item Patient Health Questionnaire (PHQ-9) and the 16-item Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR16)." Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists, vol. 5, no. 4, 2013, pp. 249-58.
Sung SC, Low CC, Fung DS, et al. Screening for major and minor depression in a multiethnic sample of Asian primary care patients: a comparison of the nine-item Patient Health Questionnaire (PHQ-9) and the 16-item Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR16). Asia Pac Psychiatry. 2013;5(4):249-58.
Sung, S. C., Low, C. C., Fung, D. S., & Chan, Y. H. (2013). Screening for major and minor depression in a multiethnic sample of Asian primary care patients: a comparison of the nine-item Patient Health Questionnaire (PHQ-9) and the 16-item Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR16). Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists, 5(4), 249-58. https://doi.org/10.1111/appy.12101
Sung SC, et al. Screening for Major and Minor Depression in a Multiethnic Sample of Asian Primary Care Patients: a Comparison of the Nine-item Patient Health Questionnaire (PHQ-9) and the 16-item Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR16). Asia Pac Psychiatry. 2013;5(4):249-58. PubMed PMID: 24123813.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Screening for major and minor depression in a multiethnic sample of Asian primary care patients: a comparison of the nine-item Patient Health Questionnaire (PHQ-9) and the 16-item Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR16). AU - Sung,Sharon Cohan, AU - Low,Charity Cheng Hong, AU - Fung,Daniel Shuen Sheng, AU - Chan,Yiong Huak, Y1 - 2013/10/03/ PY - 2013/02/04/received PY - 2013/07/23/accepted PY - 2013/10/15/entrez PY - 2013/10/15/pubmed PY - 2014/10/28/medline KW - depression KW - depressive disorder KW - primary health care KW - questionnaire KW - self-report SP - 249 EP - 58 JF - Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists JO - Asia Pac Psychiatry VL - 5 IS - 4 N2 - INTRODUCTION: Depression is common, disabling, and the single most important factor leading to suicide, yet it is underdiagnosed in busy primary care settings. A key challenge facing primary care clinicians in Asia is the selection of instruments to facilitate depression screening. Although the nine-item Patient Health Questionnaire (PHQ-9) and 16-item Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR16) are used internationally, they have not been directly compared or widely validated in Asian primary care populations. This study aimed to validate the PHQ-9 and QIDS-SR16 against a structured interview diagnosis of Diagnostic and Statistical Manual, 4th Edition, depression based on the Mini-International Neuropsychiatric Interview in a multiethnic Asian sample. METHODS: From April through August 2011, we enrolled 400 English-speaking Singaporean primary care patients. Participants completed a demographic data form, the PHQ-9, and the QIDS-SR16 . They were assessed independently for major and minor depression using the Mini-International Neuropsychiatric Interview. RESULTS: Sensitivity and specificity for diagnosing major depression were 91.7% and 72.2%, respectively, for the PHQ-9 (optimal cutoff score of 6), and 83.3% and 84.7%, respectively, for the QIDS-SR16 (optimal cutoff score of 9). The QIDS-SR16 also detected minor depression at an optimal cutoff score of 7, with a sensitivity of 94.4% and specificity of 77.9%. The PHQ-9 and QIDS-SR16 showed good internal consistency (Cronbach's α: 0.87 and 0.79, respectively) and good convergent validity (correlation coefficient: r = 0.73, P < 0.001). The overall prevalence of major and minor depressive disorders was 9%. DISCUSSION: The PHQ-9 and QIDS-SR16 appear to be valid and reliable for depression screening in Asian primary care settings. SN - 1758-5872 UR - https://www.unboundmedicine.com/medline/citation/24123813/Screening_for_major_and_minor_depression_in_a_multiethnic_sample_of_Asian_primary_care_patients:_a_comparison_of_the_nine_item_Patient_Health_Questionnaire__PHQ_9__and_the_16_item_Quick_Inventory_of_Depressive_Symptomatology___Self_Report__QIDS_SR16__ L2 - https://doi.org/10.1111/appy.12101 DB - PRIME DP - Unbound Medicine ER -